Category: 2018, No. 11

Applications of CRISPR/Cas9 genome editing technology in gene therapy for hereditary eye diseases

Authors:  Wu Shijing,  Sui Ruifang DOI: 10.3760/cma.j.issn.2095-0160.2018.11.016 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 892-896. Abstract                               [Download PDF] [Read Full Text] Clustered regulatory interspaced short palindromic repeat (CRISPR)/CRISPR associated nuclease (Cas) system is an adaptive immune system that confers resistance to exogenous virus or plasmid […]

Research progress of ocular surface reconstruction with ex vivo cultured tissue engineered cell sheet

Authors:  Wang Fuyan,  Zhou Qingjun,  Xie Lixin DOI: 10.3760/cma.j.issn.2095-0160.2018.11.015 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 887-891. Abstract                              [Download PDF] [Read Full Text] Limbal stem cells (LSCs), the source of corneal epithelial cells, play an important role in the ocular surface.In recent […]

Research progress of stem cells in corneal wound healing

Authors: Chen Hongli,  Yan Chenxi,  Fu Yao DOI: 10.3760/cma.j.issn.2095-0160.2018.11.014 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 883-886. Abstract                              [Download PDF] [Read Full Text] As the outermost part, cornea plays a critical role in protecting the eyeball and functions as main component of the dioptric media.Trauma, inflammation, […]

The visual basis of the biological clock “sees” the light: intrinsically photosensitive retinal ganglion cells

Authors: Zhang Jingxue,  Wang Ningli DOI: 10.3760/cma.j.issn.2095-0160.2018.11.013 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 879-882. Abstract                              [Download PDF] [Read Full Text] Mammalian eyes mediate both image-forming and non-image-forming visual functions.Non-image-forming vision provides a measure of the ambient light for the purposes […]

Research progress of stem cells in the treatment of retinal degenerative diseases

Authors: Zhang Kefan,  Qu Xiuxia,  Fan Guoping DOI: 10.3760/cma.j.issn.2095-0160.2018.11.011 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 871-877. Abstract                               [Download PDF] [Read Full Text] Eyes are important human organs, and retinal degenerative diseases can cause irreversible blindness.Up to date, cell transplantation is an important method for the […]

Research progress cellular reprogramming technology and induced pluripotent stem cells for retinal diseases treatment

Authors: Fang Lyujie,  Ding Yong,  Liang Helena,  Wong Raymond Ching-Bong DOI: 10.3760/cma.j.issn.2095-0160.2018.11.009 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 864-869. Abstract                              [Download PDF] [Read Full Text] Current advances in cellular reprogramming technology has demonstrated that the identity of a cell can be converted […]

The efficiency of micropulse laser trabeculoplasty for open angle glaucoma and ocular hypertension patients

Authors: Hong Ying,  Song Sijia,  Li Shushan,  Liu Bo,  Zhang Chun DOI: 10.3760/cma.j.issn.2095-0160.2018.11.008 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 859-863. Abstract                               [Download PDF] [Read Full Text] Objective To evaluate the efficiency and safety of micropulse laser trabeculoplasty (MLT) for open angle glaucoma (OAG) patients and ocular hypertension […]

Safety of autologous bone marrow mesenchymal stem cells transplantation in proliferative diabetic retinopathy patients

Authors: Liang Qingling,  Li Shiying,  Duan Ping,  Liu Yong,  Yin Zhengqin DOI: 10.3760/cma.j.issn.2095-0160.2018.11.007 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 852-858. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the safety of autologous bone marrow mesenchymal stem cells (ABMSCs) transplantation into the subretinal space for the treatment […]

c-Fos expression in visual cortex of infant rhesus monkeys with myopia induced by hyperopic defocus

Authors: Wu Junshu,  Sha Xiangyin,  Zheng Hua,  Liu Yinghui,  Ge Jian DOI: 10.3760/cma.j.issn.2095-0160.2018.11.006 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 847-851. Abstract                               [Download PDF] [Read Full Text] Objective To observe c-Fos expression in visual cortex of infant rhesus monkeys with myopia induced by hyperopic defocus and preliminarily investigate […]

Changes of the immune-microenvironment in retinal degeneration process of RCS rat

Authors:  Tang Huanyu,  Lu Ziyang,  He Juncai,  Gao Yuan,  Yin Zhengqin DOI: 10.3760/cma.j.issn.2095-0160.2018.11.005 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 839-846. Abstract                               [Download PDF] [Read Full Text] Objective To explore the immune-microenvironment of the retinas at different stages of retinal degeneration in Royal College of Surgeon (RCS) rats. […]