Recent progress of high-altitude environment impact on the eyes

High-altitude environment has its unique characteristics, which can cause a variety of acute and chronic mountain sicknesses.With increasing human activities at high altitude, the impact of high altitude exposure on human body has become a hotspot.Hypobaric hypoxia, strong breeze, strong radiation and excess ultraviolet exposure can induce pathophysiological changes in human body and eyes.Individual difference exists in response to high-altitude environment.In order to provide ideas for further study on the mechanisms of ocular changes at high altitude, this article reviewed the characteristics of high-altitude environment and their impact on the eyes, including visual function (vision, color vision, visual field and visual electrophysiology), intraocular pressure, ocular structures (tear film, conjunctiva, cornea, pupil, lens and fundus) and ocular treatments.