Month: September 2019

The inhibitory effect of FoxF2 shRNA on the expression of extracellular matrix of human trabecular meshwork

Authors: Liu Aihua,  Gao Meizi,  Huang Liangyu,  Liu Xun,  Su Ruihong,  Zhao Jinzhi,  Wang Liming,  Zhang Xiaomin,  Li Xiaorong,  Dong Lijie DOI: 10.3760/cma.j.issn.2095-0160.2019.06.002 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 405-410. Abstract                               [View PDF] [Read Full Text] Objective To explore the role of forkhead box F2 (FoxF2) in the extracellular matrix of trabecular […]

Opportunities and challenges for glaucoma research

Author: Zhang Xiulan DOI: 10.3760/cma.j.issn.2095-0160.2019.06.001 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 401-404. Abstract                               [View PDF] [Read Full Text] Elevation of intraocular pressure (IOP) is the most eminent risk factor for the presence and progression of glaucoma, which leads to optic nerve damages ultimately.With […]

Analysis of GJA3 mutation associated with a Chinese family with autosomal dominant congenital cataract by whole-exome sequencing

Authors:Liu Yuying,  Wan Wencui,  Yang Ge,  Pang Xuena,  Yang Guoguo,  Jin Xuemin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.011 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 916-919. Abstract                              [Download PDF] [Read Full Text] Congenital cataract is one of the important reasons for the blindness of children, and most congenital […]

Association of Gly82Ser polymorphism of RAGE gene with diabetic retinopathy in Han people with type 2 diabetes of Wuxi region

Authors:Cao Jia,  Yao Yong,  Xie Tianhua,  Gu Zheyao,  Zou Jian DOI: 10.3760/cma.j.issn.2095-0160.2016.10.009 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 910-914. Abstract                           [Download PDF] [Read Full Text] Background Receptor for advanced glycation end products (RAGE) play an important role in the process of type 2 diabetes […]

Screening of TYR gene mutations and clinical classification in oculocutaneous albinism patients

Authors:Wang Liming,  Han Ruifang,  Ying Ming,  Hao Peng,  Li Ningdong DOI: 10.3760/cma.j.issn.2095-0160.2016.10.008 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 905-909. Abstract                              [Download PDF] [Read Full Text] Background Oculocutaneous albinism (OCA) is a hereditary disease of pigment absence in eyes, skin […]

Mutation analysis of Pax6 in Chinese patients with congenital aniridia

Authors:Hao Peng,  Ying Ming,  Han Ruifang,  Wang Liming,  Li Ningdong DOI: 10.3760/cma.j.issn.2095-0160.2016.10.007 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 900-904. Abstract                               [Download PDF] [Read Full Text] Background Congenital aniridia is a rare congenital autosomal dominant disease, which is shown as aniridia of double eyes, […]

Identification of genetic mutation in a Chinese pedigree with congenital cataract by whole-exome sequencing

Authors:Bu Juan,  Liu Jing,  Pang Honglei,  Liu Feng,  Wang Lejin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.006 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 896-899. Abstract                            [Download PDF] [Read Full Text]  Background Genetic mutation remains to be the most common cause of congenital cataract.Whole exon sequencing technology is an ideal […]

The efficiency and safety assessment of Entranster™ nanoparticle carrier for CD25 siRNA transfection in rat cornea

Authors:Qin Qin,  Shi Yunjie,  Zhao Min DOI: 10.3760/cma.j.issn.2095-0160.2016.10.005 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 888-895. Abstract                              [Download PDF] [Read Full Text] Background Gene transfection is an effective therapeutic avenue to target many kinds of eye diseases.Non-viral vectors with high transfection efficiency, long-term expression, […]

Identification of pathgenic bacteria in aqueous and vitreous of endophthalmitis by 16S rDNA sequencing technique

Authors: Yang Baoxia,  Li Hong,  Kong Fanfang,  Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2016.10.004 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 883-887. Abstract                              [Download PDF] [Read Full Text] Background Endophthalmitis is a serious complication of intraocular surgery.Conventional identification methods for bacteria are becterial culture and smear method, […]

Detection and analysis of differential gene expression between benign lymphoepithelial lesion of lacrimal gland and orbital cavernous hemangioma

Authors:Li Jing,  Ge Xin,  Ma Jianmin,  Wang Xiaona,  Liu Xiao DOI: 10.3760/cma.j.issn.2095-0160.2016.10.003 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 878-882. Abstract                            [Download PDF] [Read Full Text] Background Benign lymphoepithelial lesion of lacrimal gland is not a common orbital disease in clinic, which mainly presented as […]