Category: 2016, No. 10

Screening of TYR gene mutations and clinical classification in oculocutaneous albinism patients

Authors:Wang Liming,  Han Ruifang,  Ying Ming,  Hao Peng,  Li Ningdong DOI: 10.3760/cma.j.issn.2095-0160.2016.10.008 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 905-909. Abstract                              [Download PDF] [Read Full Text] Background Oculocutaneous albinism (OCA) is a hereditary disease of pigment absence in eyes, skin […]

Mutation analysis of Pax6 in Chinese patients with congenital aniridia

Authors:Hao Peng,  Ying Ming,  Han Ruifang,  Wang Liming,  Li Ningdong DOI: 10.3760/cma.j.issn.2095-0160.2016.10.007 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 900-904. Abstract                               [Download PDF] [Read Full Text] Background Congenital aniridia is a rare congenital autosomal dominant disease, which is shown as aniridia of double eyes, […]

Identification of genetic mutation in a Chinese pedigree with congenital cataract by whole-exome sequencing

Authors:Bu Juan,  Liu Jing,  Pang Honglei,  Liu Feng,  Wang Lejin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.006 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 896-899. Abstract                            [Download PDF] [Read Full Text]  Background Genetic mutation remains to be the most common cause of congenital cataract.Whole exon sequencing technology is an ideal […]

The efficiency and safety assessment of Entranster™ nanoparticle carrier for CD25 siRNA transfection in rat cornea

Authors:Qin Qin,  Shi Yunjie,  Zhao Min DOI: 10.3760/cma.j.issn.2095-0160.2016.10.005 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 888-895. Abstract                              [Download PDF] [Read Full Text] Background Gene transfection is an effective therapeutic avenue to target many kinds of eye diseases.Non-viral vectors with high transfection efficiency, long-term expression, […]

Identification of pathgenic bacteria in aqueous and vitreous of endophthalmitis by 16S rDNA sequencing technique

Authors: Yang Baoxia,  Li Hong,  Kong Fanfang,  Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2016.10.004 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 883-887. Abstract                              [Download PDF] [Read Full Text] Background Endophthalmitis is a serious complication of intraocular surgery.Conventional identification methods for bacteria are becterial culture and smear method, […]

Detection and analysis of differential gene expression between benign lymphoepithelial lesion of lacrimal gland and orbital cavernous hemangioma

Authors:Li Jing,  Ge Xin,  Ma Jianmin,  Wang Xiaona,  Liu Xiao DOI: 10.3760/cma.j.issn.2095-0160.2016.10.003 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 878-882. Abstract                            [Download PDF] [Read Full Text] Background Benign lymphoepithelial lesion of lacrimal gland is not a common orbital disease in clinic, which mainly presented as […]

Changes of collapsin response mediator protein-2 and its phosphorylated protein levels following optic nerve injury

Authors:Chen Xiaofan,  Yuan Rongdi,  Ye Jian,  Chen Chunlin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.002 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 874-877. Abstract                            [Download PDF] [Read Full Text] Background Collapsin response mediator protein-2 (CRMP-2) can promote the growth of axons, but CRMP-2 occurs hyperphosphorylation under the induction of cyclin-dependent […]