Tag: Retinal ganglion cells

Negative regulation of autophagy in retinal ganglion cells by Opn5 through inhibiting Egr-1 nuclear translocation

Authors: Tong Liyang, He Danxue, Fu Chenxi, Zhang Lingmin, Hua Chaoqun DOI: 10.3760/cma.j.cn115989-20250514-00152 Published: 2026 -01 -10 Citation Tong Liyang, He Danxue, Fu Chenxi, et al. Negative regulation of autophagy in retinal ganglion cells by Opn5 through inhibiting Egr-1 nuclear translocation[J]. Chin J Exp Opthalmol, 2026, 44(1):19-26. DOI: 10.3760/cma.j.cn115989-20250514-00152. ABSTRACT               [Download PDF]  [Read Full […]

Effect of 7, 8-dihydroxyflavone on NMDA-induced apoptosis of retinal ganglion cells

Authors: Zhu Jing, Huang Keke, Guo Juan DOI: 10.3760/cma.j.cn115989-20240201-00030 Published: 2025 -05 -10 Citation Zhu Jing, Huang Keke, Guo Juan. Effect of 7, 8-dihydroxyflavone on NMDA-induced apoptosis of retinal ganglion cells[J]. Chin J Exp Ophthalmol, 2025, 43(05):430-437. DOI: 10.3760/cma.j.cn115989-20240201-00030. [Download PDF] [View Full Text] ABSTRACT Objective  To investigate the effect of intravitreal injection of 7, 8-dihydroxyflavone (DHF) on N-methyl-D-aspartate […]

Study on the protective mechanisms of leptin and ghrelin with retinal ganglion cells in glaucoma

Authors: Hu Keyu, Liu Hanruo DOI: 10.3760/cma.j.cn115989-20220414-00162 Published: 2025 -05 -10 Citation Hu Keyu, Liu Hanruo. Study on the protective mechanisms of leptin and ghrelin with retinal ganglion cells in glaucoma[J]. Chin J Exp Ophthalmol, 2025, 43(05):459-465. DOI: 10.3760/cma.j.cn115989-20220414-00162. [Download PDF] [View Full Text] ABSTRACT Glaucoma, a group of diseases characterized by progressive optic nerve degeneration, is the world’s first […]

Research progress on the role of lncRNAs in the occurrence and development of glaucoma

Authors: Guan Ruijuan, Yan Xin, Kang Zefeng DOI: 10.3760/cma.j.cn115989-20220221-00068 Published: 2025 -05 -10 Citation Guan Ruijuan, Yan Xin, Kang Zefeng. Research progress on the role of lncRNAs in the occurrence and development of glaucoma[J]. Chin J Exp Ophthalmol, 2025, 43(05):466-470. DOI: 10.3760/cma.j.cn115989-20220221-00068. [Download PDF] [View Full Text] ABSTRACT Glaucoma refers to a group of heterogeneous eye diseases, which […]

Mesenchymal stem cell therapies for traumatic optic nerve injury

Authors: Yuan Xiangling, Yao Yao, Ng Tsz Kin DOI: 10.3760/cma.j.cn115989-20210717-00416 Published:  2025 -01 -10 Citation Yuan Xiangling, Yao Yao, Ng Tsz Kin. Mesenchymal stem cell therapies for traumatic optic nerve injury[J]. Chin J Exp Ophthalmol, 2025, 43(1):69-79. DOI: 10.3760/cma.j.cn115989-20210717-00416. ABSTRACT                [Download PDF] [Read Full Text]  Optic nerve injury by trauma would […]

Role and significance of aging in retinal ganglion cell injury

Authors: Du Mengxian,  Shao Zhengbo,  Yuan Huiping DOI: 10.3760/cma.j.cn115989-20201009-00680 Published 2023-12-10 Cite as Chin J Exp Ophthalmol, 2023, 41(12): 1227-1230. Abstract                              [Download PDF] [Read Full Text] Aging is a degenerative process that leads to dysfunction and abnormalities of tissues and cells in vivo.In […]

Research progress of in vitro experimental models in retinal light irradiation

Authors: Xu Yihua,  Zhu Hong DOI: 10.3760/cma.j.cn115989-20200520-00364 Published 2023-12-10 Cite as Chin J Exp Ophthalmol, 2023, 41(12): 1243-1248. Abstract                             [Download PDF] [Read Full Text] With the popularity of electronic devices and the increasing environmental light pollution, more attention has been paid to the […]

Research progress of interleukin-6 playing neuroprotective effects on retinal ganglion cells

Authors: Lyu Hongli,  Wu Yuyu DOI: 10.3760/cma.j.issn.2095-0160.2015.10.020 Published 2015-10-10 Cite as Chin J Exp Ophthalmol, 2015,33(10): 957-960. Abstract                              [Download PDF] [Read Full Text] Recently, the risk factors for glaucoma is not very clear, a variety of mechanisms, such as increased intraocular pressure, […]

A pilot study on the relationship between miR-181a and RGCs in retinal ischemia-reperfusion injury model

Authors: Liu Jinnan,  He Yu,  Zhang Junjun,  Fan Wei DOI: 10.3760/cma.j.issn.2095-0160.2015.11.006 Published 2015-11-10 Cite as Chin J Exp Ophthalmol, 2015,33(11): 985-990. Abstract                                [Download PDF] [Read Full Text] Background Retinal ischemia-reperfusion (RIR) injury is a common pathologic change.Its mechanism has not been […]

Restrain of hypoxia on the expression of annexin A2 in mouse RGC-5 cells

Authors: Yan Lin,  Yang Xia,  Wang Longmei,  Dong Xiaoguang,  Xu Haifeng DOI: 10.3760/cma.j.issn.2095-0160.2015.12.006 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1077-1082. Abstract                            [Download PDF] [Read Full Text] Background Hypoxia is the main factor of retinal neovascularization and is closely associated with […]