Authors: Yang Guang, Zhang Dan, Ma Xiaopeng DOI: 10.3760/cma.j.cn115989-20191011-00437 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 743-748. Abstract [View PDF] [Read Full Text] Circular RNA (circRNA) is a closed loop molecule generated by the back-splicing of pre-mRNA.CircRNA can act as microRNA (miRNA) sponge […]
Category: 2021
Related clinical trials and prospects of gene therapy for neovascular age-related macular degeneration
Authors: Zhang Wei, Yan Hua DOI: 10.3760/cma.j.cn115989-20210113-00033 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 749-754. Abstract [View PDF] [Read Full Text] Neovascular macular degeneration (nAMD) is one of the main eye diseases causing blindness in the elderly population.Early detection and early treatment are […]
Characteristics of autosomal dominant retinal diseases and gene therapy strategies
Authors: Liu Yanbo, Pang Jijing DOI: 10.3760/cma.j.cn115989-20210329-00215 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 755-760. Abstract [View PDF] [Read Full Text] Inherited retinal diseases (IRDs), one type of the major eye diseases resulting in blindness, can be caused by more than 270 identified […]
Chinese experts consensus of treat-and-extend regimen for management of neovascular age-related macular degeneration by intravitreal injection of aflibercept (2021)
Author: Treat-and-Extend Regimen for Management of Neovascular Age-related Macular Degeneration Chinese Experts Consensus Group DOI: 10.3760/cma.j.cn115989-20210311-00162 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 577-584. Abstract [View PDF] [Read Full Text] Neovascular age-related macular degeneration (nAMD) is one of the leading causes of visual […]
Protective effect and mechanism of cx3cr1 antibody intravitreal injection in microcirculation of retinal ischemia-reperfusion injury in mice
Authors: Li Juanjuan, Chen Chen, Li Yan, Zhang Liwei DOI: 10.3760/cma.j.cn115989-20200104-00004 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 585-592. Abstract [View PDF] [Read Full Text] Objective To investigate the protective effect of C-X3-C motif chemokine receptor 1 (cx3cr1) antibody, a microglia activation inhibitor, […]
Protective effect of asiatic acid on blood-retinal barrier in diabetic rats
Authors: Fang Mengyuan, Li Qiuming, Yang Xin, Wan Weiwei, Long Yang, Liu Hongzhuo, Wan Wencui DOI: 10.3760/cma.j.cn115989-20201024-00713 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 593-601. Abstract [View PDF] [Read Full Text] Objective To investigate the protective effect of asiatic acid (AA) on blood-retinal […]
Research on screening system of myopic maculopathy based on deep convolution neural network
Authors: Shi Chunsheng, Liu Lei, Wang Yaru, Wang Zefei DOI: 10.3760/cma.j.cn115989-20191115-00495 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 602-608. Abstract [View PDF] [Read Full Text] Objective To develop a fully automatic detection system based on the deep convolution neural network (DCNN) for screening […]
Peripheral retinal fluorescence features of ultra-wide fundus fluorescein angiography in normal fundus eyes
Authors: Wang Xiaoling, Chen Changzheng, Xu Amin, Yi Zuohuizi, He Lu, Liu Juejun, Zheng Hongmei DOI: 10.3760/cma.j.cn115989-20190426-00201 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 609-613. Abstract [View PDF] [Read Full Text] Objective To analyze the peripheral retinal fluorescence characteristics of normal fundus on […]
Optical coherence tomography angiography of macula in retinopathy of prematurity children with single treatment history
Authors: Zhao Xinyu, Wu Zhenquan, Zhang Guoming DOI: 10.3760/cma.j.cn115989-20201104-00740 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 614-618. Abstract [View PDF] [Read Full Text] Objective To observe the changes of macular morphology and best corrected visual acuity (BCVA) in children with retinopathy of prematurity […]
Risk factors and treatment outcome of recurrent acanthamoeba keratitis after corneal transplantation
Authors: Feng Lijuan, Jia Yanni, Li Fengjie, Dong Chunxiao, Shi Weiyun, Wang Ting DOI: 10.3760/cma.j.cn115989-20200930-00673 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 619-625. Abstract [View PDF] [Read Full Text] Objective To investigate the risk factors and treatment outcome of recurrent Acanthamoeba keratitis (AK) […]