Category: 2023

Inhibitory effect of GALNT2 gene knockdown on apoptosis of human retinal vascular endothelial cells in high glucose culture and its mechanism

Authors: Sun Tianyang,  Geriletu,  Zhang Yufeng,  Li Chunyu,  Jin Lin,  Bao Lingjun,  Wang Jiale DOI: 10.3760/cma.j.cn115989-20221207-00576 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 846-853. Abstract                            【Download PDF】 【Read Full Text】 Objective To investigate the effect of polypeptide N-acetylgalactosaminaminyltransferase 2 (GALNT2) […]

Inhibitory effect of miR-497 on the repair of diabetic mice corneal epithelial damage by targeting wnt3a

Authors: Huang Yuqing,  Yang Yanning,  Wang Yang,  Pan Yumiao,  Cheng Simin DOI: 10.3760/cma.j.cn115989-20220108-00005 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 856-863. Abstract                           【Download PDF】 【Read Full Text】 Objective To investigate the inhibitory effect of miR-497 on the corneal epithelial healing in […]

Clinical and molecular genetic study of a Chinese Han family with X-linked retinoschisis

Wang Tingting,  Zhu Yihua,  Fan Mengjie,  Luo Xiaoling,  Zhang Linyan,  Zhang Daren,  Ding Xiaoyan,  Liu Xuyang DOI: 10.3760/cma.j.cn115989-20210922-00523 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 864-870. Abstract                            【Download PDF】 【Read Full Text】 Objective To study the clinical phenotype and molecular genetic characteristics of a Chinese Han family with […]

VPS13B gene variation and clinical phenotype of Cohen syndrome in a Chinese Han family

Authors: Li Ruimin,  Guo Qingge,  Li Ya,  You Ya,  Lei Bo DOI: 10.3760/cma.j.cn115989-20230508-00168 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 871-878. Abstract                           【Download PDF】 【Read Full Text】 Objective To analyze the pathogenicity and clinical characteristics of patients with Cohen syndrome caused […]

Association between human peripheral blood lipid levels and inflammatory indicators in patients with primary open angle glaucoma

Authors: Sun Yaru,  Liu Qingping,  Zhang Mingzhi DOI: 10.3760/cma.j.cn115989-20221129-00556 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 879-884. Abstract                            【Download PDF】 【Read Full Text】 Objective To investigate the association between serum lipid levels and inflammatory indicators in patients with primary open […]

Efficacy of scleral buckling for retinal detachment secondary to familial exudative vitreoretinopathy

Authors: Yang Qiong,  Wei Wenbin DOI: 10.3760/cma.j.cn115989-20220330-00122 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 886-890. Abstract                           【Download PDF】 【Read Full Text】 Objective To evaluate the efficacy of scleral buckling in the treatment of retinal detachment (RD) secondary to familial exudative vitreoretinopathy […]

Comparison of changes in functional optical zone and corneal morphology between SMILE and FS-LASIK in myopes

Authors: Wu Bowen,  Wu Jiaqin,  Wang Ling,  Chen Shihao DOI: 10.3760/cma.j.cn115989-20230305-00075 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 891-897. Abstract                            【Download PDF】 【Read Full Text】 Objective To compare the changes in functional optical zone (FOZ) and corneal morphology in myopes […]

Interpretation of standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

Author: Sheng Xunlun DOI: 10.3760/cma.j.cn115989-20230419-00142 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 898-903. Abstract                              【Download PDF】 【Read Full Text】 Sequencing technology has evolved rapidly with the advent of high-throughput next-generation sequencing (NGS). By adopting NGS, more and more ophthalmologists […]

Application of CRISPR/Cas9 genome editing technology in hereditary retinal diseases

Authors: Sun Xihao,  Tang shibo,  Chen Jiansu DOI: 10.3760/cma.j.cn115989-20201120-00787 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 925-930. Abstract                            【Download PDF】 【Read Full Text】 Several mutant genes for inherited retinal diseases have been identified, but effective treatments are still lacking.The clustered […]