Authors: Sun Xihao, Tang shibo, Chen Jiansu DOI: 10.3760/cma.j.cn115989-20201120-00787 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 925-930. Abstract 【Download PDF】 【Read Full Text】 Several mutant genes for inherited retinal diseases have been identified, but effective treatments are still lacking.The clustered […]
Tag: CRISPR/Cas9
Generation of VSX2 fluorescent reporter human induced pluripotent stem cells by CRISPR/Cas9 technology
Authors: Zheng Dandan, Wang Yuan, Zhang Zuming, Guan Yuanyuan, Xie Bingbing, Jin Kangxin, Xiang Mengqing, Zhong Xiufeng DOI: 10.3760/cma.j.cn115989-20200729-00535 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 814-820. Abstract [View PDF] [Read Full Text] Objective To establish a fluorescent reporter human induced pluripotent stem […]
Application of CRISPR/Cas9 genome editing technology in the research of eye diseases
Authors: Fan Xiangyu, Xu Jianjiang DOI: 10.3760/cma.j.issn.2095-0160.2018.07.015 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 553-558. Abstract [Download PDF] [Read Full Text] The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) is an adaptive immune system against invasive viruses and exogenous DNA, which is developed […]