·Experimental Research· The therapeutic effect and mechanism of small extracellular vesicles derived from mesenchymal stem cells (MSCs) on retinal light injury Yu Bo1, Wang Kang2, Zhang Mingliang1, Xing Xiaoli1, Li Xiaorong1, Zhang Xiaomin1 1Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye institute and School […]
Category: Experimental Science
Inhibitory effects of N-acetylcysteine and salubrinal on apoptosis of retinal pigment epithelial cells induced by all-trans-retinoic acid
Authors: Wu Juan, Cui Dongmei, Zeng Junwen DOI: 10.3760/cma.j.cn115989-20200414-00262 Published 2023-01-10 Cite as Chin J Exp Ophthalmol, 2023, 41(1): 16-21. Abstract [Download PDF] [Read Full Text] Objective To observe the effect of the antioxidant N-acetylcysteine (NAC) and selective endoplasmic […]
Inhibitory effect of ranibizumab on retinal oxidative stress in a rat model of choroidal neovascularization and its mechanism
Authors: Yang Yanzhen, Zhuang Xianli, Li Shujie, Zhang Ying, Yang Jiagan, Li Lulu DOI: 10.3760/cma.j.cn115989-20210930-00543 Published 2023-01-10 Cite as Chin J Exp Ophthalmol, 2023, 41(1): 22-28. Abstract [Download PDF] [Read Full Text] Objective To study the effect of ranibizumab […]
Feasibility of corneal epithelial transplantation with polyethylene glycol hydrogel membrane as a carrier for limbal stem cell deficiency
·Experimental Research· Feasibility of corneal epithelial transplantation with polyethylene glycol hydrogel membrane as a carrier for limbal stem cell deficiency Guo Yiyuan1, Xian Huimin2, Shereen Tan3, Qiang Fu3,4, Jin Xin1, Mark Daniel5, Greg.G.Qiao2, Zhang Hong1 1Department of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China; 2Department of Cardiology, The 2nd Affiliated […]
Pressure-induced differentiation of rabbit retinal stem cells into retinal ganglion cells
Authors: Dai Min, Kang Zefeng, Hu Zhulin, Li Yan DOI: 10.3760/cma.j.cn115989-20200519-00361 Published 2022-12-10 Cite as Chin J Exp Ophthalmol, 2022, 40(12): 1134-1140. Abstract [View PDF] [Read Full Text] Objective To investigate the effect of pressure on the differentiation of rabbit retinal stem […]
Promoting effect of nicotinamide on generation of neural crest stem cells derived from human embryonic stem cells
Authors: Duan Haoyun, Li Wenjing, Jia Yanni, Zhao Can, Zhou Qingjun, Li Zongyi DOI: 10.3760/cma.j.cn115989-20200624-00450 Published 2022-12-10 Cite as Chin J Exp Ophthalmol, 2022, 40(12): 1141-1148. Abstract [View PDF] [Read Full Text] Objective To investigate the role of nicotinamide (NIC) in the […]
Proteomic analysis of extraocular muscles from patients with thyroid-associated ophthalmopathy by tandem mass tag
·Experimental Research· Proteomic analysis of extraocular muscles from patients with thyroid-associated ophthalmopathy using a tandem mass tag Meng Qingyu, Liang Shuting, Wang Yi, Wang Lejin, Zhao Mingwei, Wu Xi Department of Ophthalmology, Peking University People’s Hospital, Eye Diseases and Optometry Institute, Beijing Key Laboratory […]
Inhibitory effect of ZhuJing pill variant formula medicated serum on H2O2-induced epithelial-mesenchymal transition of human RPE cells and its mechanism
Authors: Shao Yan, Zhang Yuanzhong, Yang Ning, Hang Li, Chen Chunming, Li Min, Xu Xinrong DOI: 10.3760/cma.j.cn115989-20210907-00501 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1013-1022. Abstract [View PDF] [Read Full Text] Objective To study the effect of ZhuJing pill variant […]
Inhibitory effect of epigallocatechin gallate on human Tenon fibroblasts and its mechanism
Authors: Chen Yanlei, Lin Hongliang, Wang Sheng, Qin Yongjie, Zhang Hongyang DOI: 10.3760/cma.j.cn115989-20211206-00672 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1023-1030. Abstract [View PDF] [Read Full Text] Objective To investigate the effect of epigallocatechin gallate (EGCG) on the activation […]
Inhibitory effect of gamma-secretase inhibitor on retinal neovascularization and regulative mechanism of Notch1 signal pathway
Authors: Cheng Zhixing, Xie Jie, Meng Qianli DOI: 10.3760/cma.j.cn115989-20220820-00384 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1031-1037. Abstract [View PDF] [Read Full Text] Objective To investigate the inhibitory effect and underlying mechanism of gamma-secretase inhibitor blocking Notch1 signaling on […]