Authors: Duan Haoyun, Li Wenjing, Jia Yanni, Zhao Can, Zhou Qingjun, Li Zongyi DOI: 10.3760/cma.j.cn115989-20200624-00450 Published 2022-12-10 Cite as Chin J Exp Ophthalmol, 2022, 40(12): 1141-1148. Abstract [View PDF] [Read Full Text] Objective To investigate the role of nicotinamide (NIC) in the […]
Category: Experimental Science
Proteomic analysis of extraocular muscles from patients with thyroid-associated ophthalmopathy by tandem mass tag
·Experimental Research· Proteomic analysis of extraocular muscles from patients with thyroid-associated ophthalmopathy using a tandem mass tag Meng Qingyu, Liang Shuting, Wang Yi, Wang Lejin, Zhao Mingwei, Wu Xi Department of Ophthalmology, Peking University People’s Hospital, Eye Diseases and Optometry Institute, Beijing Key Laboratory […]
Inhibitory effect of ZhuJing pill variant formula medicated serum on H2O2-induced epithelial-mesenchymal transition of human RPE cells and its mechanism
Authors: Shao Yan, Zhang Yuanzhong, Yang Ning, Hang Li, Chen Chunming, Li Min, Xu Xinrong DOI: 10.3760/cma.j.cn115989-20210907-00501 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1013-1022. Abstract [View PDF] [Read Full Text] Objective To study the effect of ZhuJing pill variant […]
Inhibitory effect of epigallocatechin gallate on human Tenon fibroblasts and its mechanism
Authors: Chen Yanlei, Lin Hongliang, Wang Sheng, Qin Yongjie, Zhang Hongyang DOI: 10.3760/cma.j.cn115989-20211206-00672 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1023-1030. Abstract [View PDF] [Read Full Text] Objective To investigate the effect of epigallocatechin gallate (EGCG) on the activation […]
Inhibitory effect of gamma-secretase inhibitor on retinal neovascularization and regulative mechanism of Notch1 signal pathway
Authors: Cheng Zhixing, Xie Jie, Meng Qianli DOI: 10.3760/cma.j.cn115989-20220820-00384 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1031-1037. Abstract [View PDF] [Read Full Text] Objective To investigate the inhibitory effect and underlying mechanism of gamma-secretase inhibitor blocking Notch1 signaling on […]
Establishment of lens opacity model in Grx2 knockout mice based on CRISPR/cas9 system and the role of Grx2 in the pathogenesis of cataract
·Experimental Research· Establishment of a lens opacity model in Grx2 knockout mice based on the CRISPR/cas9 system and the role of Grx2 in cataract pathogenesis Guo Yong1, Guo Chenjun2, Zhang Jie2, Ning Xiaona2, Chen Xi3, Yan Hong1 1Department of Ophthalmology, Xi’an People’s Hospital, Xi’an Fourth Hospital, Shaanxi Eye Hospital, Xi’an 710004, China; 2Department of Ophthalmology, […]
Classification of adenoviral conjunctivitis based on sequencing and phylogenetic analysis of hexon and fiber
Authors: Wang Jing, Zhu Jianfeng, Lu Lina DOI: 10.3760/cma.j.cn115989-20200430-00300 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 902-907. Abstract [View PDF] [Read Full Text] Objective To classify human adenovirus (HAdV) of adenoviral conjunctivitis by sequencing and […]
Protective effect of tert-butylhydroquinone on retinal morphology and function in early diabetic rats and its mechanism
·Experimental Research· Protective effects of tert-butylhydroquinone on retinal structure, function and mechanism in early diabetic rat models Wang Juan1, Wei Fang2, Cao Yang1, Tian Min1, Lyu Hongbin1 1Department of Ophthalmology, the Affiliated Hospital of Southwest Medical University, Luzhou 646000, China; 2Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, […]
Inhibitory effect of microRNA-23b-3p on high glucose-induced autophagy and apoptosis of human lens epithelial cells and its mechanism
·Experimental Research· Role and mechanism of microRNA-23b-3p in regulating high glucose-induced autophagy and apoptosis of human lens epithelial cells Liu Wenlan, Wang Li, Yang Yang, Yan Jin School of Medical Technology, Xi’an Medical University, Xi’an 710021, China Corresponding author: Wang Li, Email: 63148645@qq.com [Abstract] […]
Network pharmacology analysis of ginkgo leaves extract against diabetic retinopathy
·Experimental Research· Network pharmacology analysis of ginkgo leaf extract against diabetic retinopathy Bai Wen, Jiang Qin Eye Hospital, Nanjing Medical University, Nanjing 210029, China Corresponding author: Jiang Qin, Email: jqin710@vip.sina.com [Abstract] [View PDF in English] [View PDF in Chinese] [Read Full Text] Objective To identify the key […]