Authors: Zhang Shukun, Xie Ping, Yuan Dongqing, Liu Qinghuai DOI: 10.3760/cma.j.issn.2095-0160.2015.12.009 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1095-1101. Abstract [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) is one of the primary causes leading to visual damage in […]
Category: Experimental Science
Dynamic expression of intercellular adhesion molecule-1 in laser-induced choroidal neovascularization in Brown Norway rats
Authors: Gao Xiaoyan, He Shouzhi DOI: 10.3760/cma.j.issn.2095-0160.2015.12.011 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1103-1107. Abstract [Download PDF] [Read Full Text] Background Extracellular matrix (ECM) has various kinds of types and important biological function.The important role of ECM during choroidal […]
Modification and evaluation of ameliorative oxygen-induced retinopathy mouse model
Authors: Liu Aihua, Sun Jing, Zhang Hong DOI: 10.3760/cma.j.issn.2095-0160.2015.12.012 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1108-1112. Abstract [Download PDF] [Read Full Text] Background Retinal neovascularization is associated with various disorders.Studying the pathogenesis of retinal neovascularization is of important significance.Oxygen-induced retinopathy(OIR) […]
Protection of sulforaphane against hydrogen peroxide-induced bovine trabecular meshwork cell apoptosis
Authors: Liu Yuzhen, Wang Qiang DOI: 10.3760/cma.j.issn.2095-0160.2016.06.009 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 516-521. Abstract [Download PDF] [Read Full Text] Background Evidences indicated that oxidative stress damage is an essential pathological process in primary open angle glaucoma.Sulforaphane (SFN) can […]
Toxic effects of manganese ion eyedrops to ocular anterior segment
Authors: Lei Miao, Zhu Yu, Liang Shenzhi DOI: 10.3760/cma.j.issn.2095-0160.2016.06.008 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 510-515. Abstract [Download PDF] [Read Full Text] Background A preliminary study determined an application of manganese ion eyedrops in tracing observation of visual system […]
Protective effect of NLRP12 knockdown on retinal damage in rats with ocular hypertension and its mechanism of inhibiting cell pyroptosis
Authors: Song Weiqiong, He Fang, Du Lingfang, Tan Huaxia, Liu Dan DOI: 10.3760/cma.j.cn115989-20211021-00572 Published 2023-02-10 Cite as Chin J Exp Ophthalmol, 2023, 41(2): 110-118. Abstract [Download PDF] [Read Full Text] Objective To investigate the effect and mechanism of NOD-like receptor family pyrin […]
Promoting effect of AGTR1 blocker olmesartan on the apoptosis of HTF and its mechanism
Authors: Wang Lijun, Li Hongsong, Zhang Wenyi, Shao Meilin, Ren Meimei, Wang Jianming DOI: 10.3760/cma.j.cn115989-20220601-00262 Published 2023-02-10 Cite as Chin J Exp Ophthalmol, 2023, 41(2): 119-126. Abstract [Download PDF] [Read Full Text] Objective To study the effect and mechanism of angiotensin type 1 […]
Search for potential target genes in dexamethasone-induced open-angle glaucoma by bioinformatics
·Experimental Research· Potential target genes detected by bioinformatics in dexamethasone-induced open-angle glaucoma Liu Liling, Li Deling, Zeng Weiting, Zhang Xinyi, Xu Jiangang, Yu Minbin State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Certer, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou 510060, China Corresponding author: Yu Minbin, Email: yuminbin@mail.sysu.edu.cn Abstract […]
Therapeutic effect of small extracellular vesicles derived from mesenchymal stem cells on retinal light injury and its mechanism
·Experimental Research· The therapeutic effect and mechanism of small extracellular vesicles derived from mesenchymal stem cells (MSCs) on retinal light injury Yu Bo1, Wang Kang2, Zhang Mingliang1, Xing Xiaoli1, Li Xiaorong1, Zhang Xiaomin1 1Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye institute and School […]
Inhibitory effects of N-acetylcysteine and salubrinal on apoptosis of retinal pigment epithelial cells induced by all-trans-retinoic acid
Authors: Wu Juan, Cui Dongmei, Zeng Junwen DOI: 10.3760/cma.j.cn115989-20200414-00262 Published 2023-01-10 Cite as Chin J Exp Ophthalmol, 2023, 41(1): 16-21. Abstract [Download PDF] [Read Full Text] Objective To observe the effect of the antioxidant N-acetylcysteine (NAC) and selective endoplasmic […]