Authors: Chen Yuan, Xing Qian, Huang Zhengru DOI: 10.3760/cma.j.cn115989-20191215-00543 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1011-1015. Abstract [View PDF] [Read Full Text] Objective To explore the pharmacological molecular mechanisms of metformin against diabetic retinopathy (DR) based on network pharmacology approach. Methods After […]
Category: Experimental Science
Anti-apoptosis and anti-inflammation effects and mechanism of berberine on high-concentration glucose induced rat retinal Müller cells
Authors: Jin Yiping, Zhu Haohao, Liao Yujie, Yu Xiaoyan DOI: 10.3760/cma.j.cn115989-20200917-00647 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1016-1024. Abstract [View PDF] [Read Full Text] Objective To investigate the effects of berberine on Sprague Dawley (SD) rat retinal Müller cells cultured by high […]
Protective effect and mechanism of esculetin on oxidative damaged ARPE-19 cells
Authors: Zhang Yingjun, Bai Ge, He Xiangdong, Zhang Donglei, He Wei DOI: 10.3760/cma.j.cn115989-20200224-00101 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1025-1031. Abstract [View PDF] [Read Full Text] Objective To study the protective effect and the mechanism of esculetin on oxidative-stressed human retinal pigment […]
Ocular pharmacokinetics of econazole solid lipid nanoparticle eye drops after single dose topical administration in rabbits
Authors: Liang Zhen, Zhang Zhen, Li Jingguo, Yang Jingjing, Lu Ping, Zhou Tianyang, Zhang Junjie DOI: 10.3760/cma.j.cn115989-20191008-00429 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1032-1037. Abstract [View PDF] [Read Full Text] Objective To investigate the pharmacokinetics of econazole solid lipid nanoparticles (E-SLNs) after […]
Ocular pharmacokinetics of topical administration of butenafine nanomicelles in rabbit eyes
Authors: Lu Ping, Liang Zhen, Zhang Zhen, Yang Jingjing, Song Fei, Li Jingguo, Zhou Tianyang, Zhang Junjie DOI: 10.3760/cma.j.cn115989-20200526-00374 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1038-1044. Abstract [View PDF] [Read Full Text] Objective To study the pharmacokinetics of the broad-spectrum antifungal drug […]
Stability evaluation of different internal fixation methods for zygomaticomaxillary complex fractures by finite element biomechanical analysis
Authors: Li Yan, Wu Pengsen, Ma Yue, Tang Meiting, Zeng Xueying, Tang Yuanyuan, Yu Shen, Lu Wei DOI: 10.3760/cma.j.cn115989-20200727-00529 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 916-922. Abstract [View PDF] [Read Full Text] Objective To analyze the stability of different internal fixation methods […]
Effects of IL-17A and IFN-γ on the fibrosis of CD34- orbital fibroblasts in Graves orbitopathy
Authors: Lu Yi, Huang Yazhuo, Li Yinwei, Wu Yu, Fang Sijie, Sun Jing, Zhou Huifang DOI: 10.3760/cma.j.cn115989-20200719-00513 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 923-928. Abstract [View PDF] [Read Full Text] Objective To observe the effects of interleukin-17A (IL-17A) and interferon-γ (IFN-γ) on […]
Inhibitory effects of resveratrol on high glucose-induced apoptosis of retinal cells
Authors: Li Qingchun, Li Dai, Xing Yiqiao DOI: 10.3760/cma.j.cn115989-20200519-00351 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 929-935. Abstract [View PDF] [Read Full Text] Objective To investigate the inhibitory effects of resveratrol (Res) on the apoptosis of retinal neurons of diabetic rats and ARPE-19 […]
Effects of early applying basic fibroblast growth factor on corneal haze after surface ablation surgery and its mechanism
Authors: Sui Wenjun, Gao Honglian, Liu Qiqi, Zhang Lei DOI: 10.3760/cma.j.cn115989-20190418-00190 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 936-943. Abstract [View PDF] [Read Full Text] Objective To investigate the effects of early applying of basic fibroblast growth factor (bFGF) […]
Generation of VSX2 fluorescent reporter human induced pluripotent stem cells by CRISPR/Cas9 technology
Authors: Zheng Dandan, Wang Yuan, Zhang Zuming, Guan Yuanyuan, Xie Bingbing, Jin Kangxin, Xiang Mengqing, Zhong Xiufeng DOI: 10.3760/cma.j.cn115989-20200729-00535 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 814-820. Abstract [View PDF] [Read Full Text] Objective To establish a fluorescent reporter human induced pluripotent stem […]