Category: Experimental Science

Contrast of retinal structure and function developing of premature rats versus full-term newborn rats

Authors: Yang Xiangmin,  Li Rong,  Wang Yusheng,  Su Jingbo,  An Jing,  Chen Tao,  Cao Qinglin,  Zhang Zuoming DOI: 10.3760/cma.j.issn.2095-0160.2016.01.010 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 49-55. Abstract                            [Download PDF] [Read Full Text] Background Premature birth is a high risk factor of abnormal development in the morphology and function of vision system.To […]

Expression changes of brain-derived neurotrophic factor in retina of oxygen-induced retinopathy

Authors: Duan Haixia,  Guo Kai,  Wang Banwei DOI: 10.3760/cma.j.issn.2095-0160.2016.01.011 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 56-59. Abstract                              [Download PDF] [Read Full Text] Background Neovascular diseases such as retinopathy of prematurity often leads to irreversible vision loss.The study on oxidative damage mechanism is becoming more and […]

Dysfunction of tear film and ultrastructural changes of corneal epithelial cells in castrated male mice

Authors: Li Li,  Wang Shuangmei,  Zheng Xuan,  Kang Qianyan DOI: 10.3760/cma.j.issn.2095-0160.2016.02.002 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 103-107. Abstract                            [Download PDF] [Read Full Text] Background Studies indicate that the decline of androgen level affects the secretion function of epithelial cells of meibomian glands and lacrimal glands, which […]

Protective effects of thymosin β4 on ethanol-induced rabbit corneal epithelial cell damage in vitro

Authors: Jiang Zhixin,  Hao Peng,  Tang Xin,  Li Xuan DOI: 10.3760/cma.j.issn.2095-0160.2016.02.003 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 108-114. Abstract                              [Download PDF] [Read Full Text] Background Laser assisted subepithelial keratomileusis (LASEK) is one of surgical procedures for refractive correction. Dilute alcohol that is used for the removal […]

Inhibitory effect of miR-204 on corneal epithelial cell proliferation in vitro

Authors: Liang Rongxin,  Du Jinlin,  Huang Tao DOI: 10.3760/cma.j.issn.2095-0160.2016.02.005 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 116-120. Abstract                              [Download PDF] [Read Full Text] Background As the main cellular constituent of corneal epithelium, corneal epithelial cells play critical roles in regulating and controlling the migration, proliferation and […]

Feasibility of bacterial cellulose membrane as biological scaffold for construction of tissue engineering corneal epithelium

Authors: Cao Jingjie,  Zhang Chen,  Zhao Shaozhen,  Wan Yizao,  Hu Da DOI: 10.3760/cma.j.issn.2095-0160.2016.02.006 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 121-124. Abstract                              [Download PDF] [Read Full Text] Background Corneal transplantation is a primary method for the treatment of serious corneal diseases, but its application […]

Pathogenesis and treatment of overwhelming inflammation induced by Pseudomonas aeruginosa keratitis in rabbit

Authors: Liang Qingfeng,  Li Bin,  Zhang Yang,  Labbe Antoine DOI: 10.3760/cma.j.issn.2095-0160.2016.02.007 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 125-131. Abstract                            [Download PDF] [Read Full Text] Background Infectious keratitis is common blinding eye disease in China. Inflammatory runaway reaction often occurs in infectious keratitis, and its mechanism and treating […]

Isolation and culture of corneal neovascular endothelial cells and expression of chemokine receptors

Authors: Liu Gaoqin,  Xiao Yanhui,  Chen Zhigang,  Xu Jing,  Lu Peirong DOI: 10.3760/cma.j.issn.2095-0160.2016.02.008 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 132-136. Abstract                            [Download PDF] [Read Full Text] Background The pathogenesis and mechanism research of corneal neovascularization is of important significance for the prevention and management of corneal neovascularization. Some […]

Construction of Smac siRNA lentiviral vector and its silencing effect on Smac gene in human LECs

Authors: Li Yun,  Zheng Guangying,  Jiang Yu DOI: 10.3760/cma.j.issn.2095-0160.2016.03.002 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 199-204. Abstract                              [Download PDF] [Read Full Text] Background Research comfirmed that second mitochondrial activator of caspase (Smac) is a promoting tumor cell apoptosis protein.Our previous study showed that the expression […]

Expression and its significance of aquaporin0 and 1 in lens with age-related cataract

Authors: Zhan Zhiyun,  Xu Guoxing,  Xie Maosong DOI: 10.3760/cma.j.issn.2095-0160.2016.03.003 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 205-209. Abstract                            [Download PDF] [Read Full Text] Background Age-related cataract is a common cause of blindness.However, its cause and pathogenic mechanism have not been fully understood.Recent studies revealed that aquaporin 1 […]