Authors: Yang Baoxia, Wang Ye, Zhao Xiaowen, Liu Ting, Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2016.03.004 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 210-217. Abstract [Download PDF] [Read Full Text] Background Epithelial-mesenchymal transition (EMT) is one of the pathogenesis mechanisms of posterior capule opcification (PCO). Studying EMT is of important significance […]
Category: Experimental Science
The regulation of estradiol on growth dynamics of human LECs affected by increasing telomerase activity
Authors: Wang Jie, Kang Gangjin, Yuan Xuefeng, Xu Manhua, Jiang Yan, Luo Bo DOI: 10.3760/cma.j.issn.2095-0160.2016.03.006 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 219-225. Abstract [Download PDF] [Read Full Text] Background Human LECs can express telomerase activity, which participates in the formation of cataract.It is reported that estrogen can increase […]
Anti-oxydative effects of miR-204 on LECs in age-related cataract
Authors: Su Xianhua, Wang Ye, Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2016.03.008 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 227-233. Abstract [Download PDF] [Read Full Text] Background miRNAs are a group of non-coding small RNA molecules, and they play an important role in regulating the apoptosis of LECs.The biological effects […]
Negative regulation of exogeneous polyl-4-hydroxylase domain proteins on hypoxia-inducible factor pathway in human RPE cells
Authors: Ma Yu, Tang Shaohua, Jiang Yanrong, Shi Xuan DOI: 10.3760/cma.j.issn.2095-0160.2016.03.009 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 234-238. Abstract [Download PDF] [Read Full Text] Background Anti-VEGF drugs are generally applied in the treatment of ocular neovascular diseases.However, the therapy effect is unsatisfactory […]
Differentially expressed genes analysis of retinal vascular endothelial cells under hyperglycemia and hyperlipidemia induced by α-melanocyte-stimulating hormone
Authors:Wu Mianmian, Guo Fang, Li Yahong, Liu Ke, Zhang Yan DOI: 10.3760/cma.j.issn.2095-0160.2019.09.002 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 694-700. Abstract [View PDF] [Read Full Text] Objective To investigate the effect of α-melanocyte-stimulating hormone(α-MSH) on the expression of mRNA and long noncoding RNA (lncRNA) […]
Analysis of differentially expressed genes of Staphylococcus aureus isolated from corneal ulcer and healthy conjunctival sac
Authors:Liu Qing, Dong Yanling, Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2019.09.003 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 701-706. Abstract [View PDF] [Read Full Text] Objective To investigate the possible pathogenesis of Staphylococcus aureus (S.aureus) corneal ulcer by analyzing the differentially expressed genes (DEGs) of S.aureus isolated from the patients with […]
Proteomic research of human retinal microvascular pericytes stimulated with high glucose
Authors:Xiao Mengran, Zhang Xiaomin, Shao Xianfeng, Xiao Jing, Yang Fuhua, Zhang Hui, Ea Vicki L, Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2019.09.004 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 707-712. Abstract [View PDF] [Read Full Text] Objective To determine the changes of protein expressions in human retinal […]
Effect and potential signaling pathway of hedgehog protein on the function of human retinal microvascular endothelial cell
Authors:Li Yang, Hu Qinrui, Wang Bin, Xia Huika, Zhang Xiaohu DOI: 10.3760/cma.j.issn.2095-0160.2019.09.005 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 713-718. Abstract [View PDF] [Read Full Text] Objective To explore the impact of Hedgehog protein on human retinal microvascular endothelial cell(HRMEC)and its signaling pathway. Methods […]
Mutations analysis of FRMD7 gene in idiopathic congenital nystagmus families
Authors:Du Wei, Zhang Ye, Xie Zhenggao DOI: 10.3760/cma.j.issn.2095-0160.2019.09.008 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 726-729. Abstract [View PDF] [Read Full Text] Objective To reveal the pathogenic mutations in Chinese families with idiopathic congenital nystagmus(ICN) Methods Six families with ICN were recruited from Subei […]
Diabetic retinopathy detection algorithm based on transfer learning
Authors:Huang Yijin, Lyu Junyan, Li Meng, Xia Honghui, Yuan Jin, Tang Xiaoying DOI: 10.3760/cma.j.issn.2095-0160.2019.08.003 Published 2019-08-10 Cite as Chin J Exp Ophthalmol, 2019,37(8): 603-607. Abstract [View PDF] [Read Full Text] Objective To investigate a diabetic retinopathy (DR) detection algorithm based on transfer learning in small sample […]