Category: Experimental Science

Establishment of chronic ocular hypertension rat model by transgoniscope laser photocoagulation to trabecular meshwork and its comparison with translimbal laser photocoagulation

Authors: Ma Di,  Huang Chukai,  Cen Lingping,  Zhang Mingzhi DOI: 10.3760/cma.j.issn.2095-0160.2016.07.002 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 580-584. Abstract                              [Download PDF] [Read Full Text] Background The establishment of chronic ocular hypertension is a basis for the research of glaucoma.Previous laser photocoagulation method to […]

Formation of cell sheet on acellular porcine corneal stroma with human corneal endothelial cells cocultured by mouse embryonic stem cell conditioned medium

Authors: Lu Xiaoyan,  Wang Zhichong DOI: 10.3760/cma.j.issn.2095-0160.2016.08.007 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 705-709. Abstract                              [Download PDF] [Read Full Text] Background Corneal transplantation faces a great challenge because of the shortage of corneal donors and difficulty of human corneal endothelial cells (HCECs) regeneration in […]

Inhibitory effect of curcumin, salvia miltiorrhiza and matrine on IL-1β-induced proliferation of rabbit RPE cells in vitro

Authors: Liu Liya,  Ma Jingxue,  An Jianbin,  Liu Danyan,  Gao Yanjun,  Zhou Nalei,  Ma Yuelei DOI: 10.3760/cma.j.issn.2095-0160.2016.08.006 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 699-704. Abstract                            [Download PDF] [Read Full Text] Background Proliferative vitreoretinopathy (PVR) is a common cause of vision loss clinically, and retinal […]

A study on the establishment of co-culture system of peripheral blood mononuclear cells with orbital fibroblasts and the secretion of IL-6 and IL-17A induced by phytagglutinin in thyroid associated ophthalmopathy

Authors: Pan Yuan,  Xu Xueliang,  Tan Jia,  Xu Bei,  Zhang Lingli DOI: 10.3760/cma.j.issn.2095-0160.2016.08.005 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 692-698. Abstract                              [Download PDF] [Read Full Text] Background The pathogenic mechanism of thyroid associated ophthalmopathy (TAO) is still unclear, which is considered to be […]

The dynamic changes of regulatory T cells in the pathogenesis of experimental autoimmune uveitis

Authors: Zhang Lian,  Song Jike,  Tang Kai,  Zheng Fengming,  Guo Junguo,  Bi Hongsheng DOI: 10.3760/cma.j.issn.2095-0160.2016.08.003 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 684-690. Abstract                            [Download PDF] [Read Full Text] Background Studies show that regulatory T cells (Treg) are a kind of T cell subsets to […]

Induction of docosahexaenoic acid to expression of heme oxygenase-1 in retinal pigment epithelial cells

Authors: Liu Yuefeng,  Luo Weimin,  Zhang Yong,  Zhong Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2016.08.002 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 677-683. Abstract                            [Download PDF] [Read Full Text] Background Oxydative stress is an important pathogenesis of age-related macular degeneration.Resent evidences indicate that docosahexaenoic acid (DHA) plays an important […]

A pilot study on indunction and differentiation of human fibroblasts to iPS cells and iPS-RPE cells mediated by retrovirus infection

Authors: Tian Yuanyuan,  Jiang Chao,  Chen Xue,  Ding Sijia,  Xu Min,  Zhao Chen DOI: 10.3760/cma.j.issn.2095-0160.2016.09.006 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 793-798. Abstract                              [Download PDF] [Read Full Text] Background Retinal pigment epithelium (RPE) cell transplantation is the primary means of human trial for the treatment of retinal degeneration.Induced […]

Optimization of ultrastructure observation of human embryonic stem cell-derived retinal pigment epithelial cells

Authors: Wu Wei,  Qu Ya,  Wang Lei,  Zeng Yuxiao,  Xu Haiwei,  Yin Zhengqin  DOI: 10.3760/cma.j.issn.2095-0160.2016.09.004 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 786-790. Abstract                               [Download PDF] [Read Full Text] Background Normal ultrastructure is the anatomical basis of retinal pigment epithelial(RPE)cells to perform normal physiological function.At present the precipitation method […]

Therapeutic effect and mechanism of human umbilical cord mesenchymal stem cell transplantation for Sjögren syndrome in mice

Authors: Huang Shouqiang,  Fu Yanxia,  Mao Kejie,  Zhang Xu,  Zhang Cheng,  Peng Xiujun DOI: 10.3760/cma.j.issn.2095-0160.2016.09.003 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 780-785. Abstract                              [Download PDF] [Read Full Text] Background The incidence of dry eye is gradually increased, and researches showed that inflammation participated in the pathogenesis and development […]

In vitro effects of bone marrow-derived mesenchymal stem cells on the biological behavior of lipopolysaccharide-activated retinal microglia

Authors: Huang Libin,  Xu Guoxing,  Xie Maosong,  Lin Wen,  Cui Yi,  Li Jianbing DOI: 10.3760/cma.j.issn.2095-0160.2016.09.002 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 773-779. Abstract                              [Download PDF] [Read Full Text] Background Retinal microglia(RMG) plays an important role in the pathogenesis of retinal degenerative diseases, while chemokine CX3CL1 participates in the […]