Authors: Liu Yuefeng, Luo Weimin, Zhang Yong, Zhong Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2016.08.002 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 677-683. Abstract [Download PDF] [Read Full Text] Background Oxydative stress is an important pathogenesis of age-related macular degeneration.Resent evidences indicate that docosahexaenoic acid (DHA) plays an important […]
Category: Experimental Science
A pilot study on indunction and differentiation of human fibroblasts to iPS cells and iPS-RPE cells mediated by retrovirus infection
Authors: Tian Yuanyuan, Jiang Chao, Chen Xue, Ding Sijia, Xu Min, Zhao Chen DOI: 10.3760/cma.j.issn.2095-0160.2016.09.006 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 793-798. Abstract [Download PDF] [Read Full Text] Background Retinal pigment epithelium (RPE) cell transplantation is the primary means of human trial for the treatment of retinal degeneration.Induced […]
Optimization of ultrastructure observation of human embryonic stem cell-derived retinal pigment epithelial cells
Authors: Wu Wei, Qu Ya, Wang Lei, Zeng Yuxiao, Xu Haiwei, Yin Zhengqin DOI: 10.3760/cma.j.issn.2095-0160.2016.09.004 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 786-790. Abstract [Download PDF] [Read Full Text] Background Normal ultrastructure is the anatomical basis of retinal pigment epithelial(RPE)cells to perform normal physiological function.At present the precipitation method […]
Therapeutic effect and mechanism of human umbilical cord mesenchymal stem cell transplantation for Sjögren syndrome in mice
Authors: Huang Shouqiang, Fu Yanxia, Mao Kejie, Zhang Xu, Zhang Cheng, Peng Xiujun DOI: 10.3760/cma.j.issn.2095-0160.2016.09.003 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 780-785. Abstract [Download PDF] [Read Full Text] Background The incidence of dry eye is gradually increased, and researches showed that inflammation participated in the pathogenesis and development […]
In vitro effects of bone marrow-derived mesenchymal stem cells on the biological behavior of lipopolysaccharide-activated retinal microglia
Authors: Huang Libin, Xu Guoxing, Xie Maosong, Lin Wen, Cui Yi, Li Jianbing DOI: 10.3760/cma.j.issn.2095-0160.2016.09.002 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 773-779. Abstract [Download PDF] [Read Full Text] Background Retinal microglia(RMG) plays an important role in the pathogenesis of retinal degenerative diseases, while chemokine CX3CL1 participates in the […]
The effect of tanshinone on meibomian gland cell proliferation, differentiation and lipid synthesis
Authors: Lai Qinghua, Gao Yingying, Li Wei, Zuo Chengyou, Li Qingmin DOI: 10.3760/cma.j.issn.2095-0160.2019.06.006 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 432-438. Abstract [View PDF] [Read Full Text] Objective To investigate the effects of cryptotanshinone and tanshinone ⅡA, two major monomer components of tanshinone, on the proliferation, differentiation and […]
Protective effects of intravitreal injection of nerve growth factor on retinal ganglion cells in early diabetic rats
Authors: Lyu Hang, Wang Qichang, Tang Luosheng DOI: 10.3760/cma.j.issn.2095-0160.2019.06.005 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 425-431. Abstract [View PDF] [Read Full Text] Objective To investigate the protective effect of intravitreal injection of nerve growth factor (NGF) on apoptosis of retinal ganglion cells (RGCs) in early […]
Dynamic changes of ocular surface tissue of diabetic dry eye in mice
Authors: Wang Qian, Wan Lei, Li Jing, Zhou Qingjun DOI: 10.3760/cma.j.issn.2095-0160.2019.06.004 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 419-424. Abstract [View PDF] [Read Full Text] Objective To explore the occurring and developing characteristics of dry eye syndrome in type 1 diabetic mouse model induced with streptozotocin (STZ)-intraperitoneal […]
The effect and mechanisms of chloride channel blocker NPPB on TGF-β1 induced HConF fibrosis
Authors: Sun Lixia, Li Yingjun, Cui Renzhe, Lu Di, Zheng Yajuan DOI: 10.3760/cma.j.issn.2095-0160.2019.06.003 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 411-418. Abstract [View PDF] [Read Full Text] Objective To study the effect and mechanisms of chloride channel blocker 5-Nitro-2-(3-phenylpropylamino) benzoic acid (NPPB) on thansforming growth factor β1 (TGF-β1) […]
The inhibitory effect of FoxF2 shRNA on the expression of extracellular matrix of human trabecular meshwork
Authors: Liu Aihua, Gao Meizi, Huang Liangyu, Liu Xun, Su Ruihong, Zhao Jinzhi, Wang Liming, Zhang Xiaomin, Li Xiaorong, Dong Lijie DOI: 10.3760/cma.j.issn.2095-0160.2019.06.002 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 405-410. Abstract [View PDF] [Read Full Text] Objective To explore the role of forkhead box F2 (FoxF2) in the extracellular matrix of trabecular […]