Authors: Xue Yunxia, Ma Zhenglai, Li Zhijie, Yang Xuesong DOI: 10.3760/cma.j.issn.2095-0160.2016.09.007 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 799-803. Abstract [Download PDF] [Read Full Text] Background To understand the distribution and development of corneal nerve in animal or human has an important significance for clinical and basic […]
Category: Experimental Science
Effects of sulforaphane on thioredoxin expression in bovine trabecular meshwork cells
Authors: Su Jing, Wang Qiang, Liu Yuzhen DOI: 10.3760/cma.j.issn.2095-0160.2016.06.006 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 504-508. Abstract [Download PDF] [Read Full Text] Background Recent studies have confirmed that sulforaphane (SFN) can activate multiple pathways, and promote the expression of the antioxidants in cells.Thioredoxin […]
Protecting effects and mechanism of tert-butyl hydroquinone on retinal cells in type 2 diabetic rats
Authors: Han Peiyan, Zhang Siyuan, Li Jingyan, Huang Qi, Tian Min, Lyu Hongbin DOI: 10.3760/cma.j.issn.2095-0160.2016.06.004 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 496-502. Abstract [Download PDF] [Read Full Text] Background Apoptosis is a primary clinical pathological mechanism of diabetic retinopathy […]
The sustained releasing ability of CEL-PLGA-MS in vitro and its inhibitory effects on experimental choroidal neovascularization after intravitreal injection
Authors: Chen Pengfei, Hao Yuhua, Yang Na, An Jianbin, Liu Liya, Ma Jingxue DOI: 10.3760/cma.j.issn.2095-0160.2016.06.003 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 489-495. Abstract [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) is a common pathological basis of many ocular fundus diseases.Some treating methods […]
Rapid differentiation of human ESCs into RPE cells by defined xeno-free culture system
Authors: Liu Qiuhui, Wang Jing, Tian Rong, Wang Xiao, Cao Di, Lu Jing, Luo Yan DOI: 10.3760/cma.j.issn.2095-0160.2016.06.002 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 484-488. Abstract [Download PDF] [Read Full Text] Background Subretinal transplantation of retinal pigment epithelium (RPE) cells for the treatment of age-related […]
Wnt3a-induced extracellular matrix production and gel contraction in human lens epithelial cells
Authors: Bao Xiuli, Liu Tingting, Wang Yanyan, Li Lin DOI: 10.3760/cma.j.issn.2095-0160.2016.07.005 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 597-601. Abstract [Download PDF] [Read Full Text] Background Excessive production, deposition and contraction of extracellular matrix (ECM) of human lens endothelial cells (LECs) is one of […]
Inhibitory effects of bevacizumab on filtering bleb scarring following trabeculectomy in rabbits
Authors: Liang Pei, Yang Jin, Lin Jinyong DOI: 10.3760/cma.j.issn.2095-0160.2016.07.004 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 591-596. Abstract [Download PDF] [Read Full Text] Background The primary reason to trabeculectomy failure is fibrosis of conjunctiva and episclera because of progressive fibroblast proliferation and collagen deposition […]
Anti-scarring effects of triamcinolone acetonide/polylactic acid caprolactone drug-loaded electrospinning film with trabeculectomy in rabbits
Authors: Zheng Yuqiang, Wang Zhuoshi, Xu Ling, Wu Jianguo, Zhao Jun, He Wei DOI: 10.3760/cma.j.issn.2095-0160.2016.07.003 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 585-590. Abstract [Download PDF] [Read Full Text] Background Scarring of filter bleb is a main cause of failure after trabeculectomy.Administration of anti-proliferation […]
Establishment of chronic ocular hypertension rat model by transgoniscope laser photocoagulation to trabecular meshwork and its comparison with translimbal laser photocoagulation
Authors: Ma Di, Huang Chukai, Cen Lingping, Zhang Mingzhi DOI: 10.3760/cma.j.issn.2095-0160.2016.07.002 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 580-584. Abstract [Download PDF] [Read Full Text] Background The establishment of chronic ocular hypertension is a basis for the research of glaucoma.Previous laser photocoagulation method to […]
Formation of cell sheet on acellular porcine corneal stroma with human corneal endothelial cells cocultured by mouse embryonic stem cell conditioned medium
Authors: Lu Xiaoyan, Wang Zhichong DOI: 10.3760/cma.j.issn.2095-0160.2016.08.007 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 705-709. Abstract [Download PDF] [Read Full Text] Background Corneal transplantation faces a great challenge because of the shortage of corneal donors and difficulty of human corneal endothelial cells (HCECs) regeneration in […]