Category: Experimental Science

Comparison of retinal histomorphology following laser photocoagulation using 577 nm subliminal micropulse laser versus 577 nm laser in pigmented rabbits

Authors: Li Huili,  Wang Chunyan,  Li Xiaodan,  Yu Hai,  Fu Yan DOI: 10.3760/cma.j.issn.2095-0160.2017.09.011 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 824-828. Abstract                              [Download PDF] [Read Full Text] Background Studies showed that 577 nm subliminal micropulse photocoagulation for retinal diseases is more effective and much […]

Mediated effects of endoplasmic reticulum stress on light-induced apoptosis and inflammation of human retinal pigment epithelial cell

Authors: Jiang Wenjing,  Zhang Lina,  Yu Xiao,  Niu Yingjun DOI: 10.3760/cma.j.issn.2095-0160.2017.09.010 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 816-823. Abstract                               [Download PDF] [Read Full Text] Background The light damage model of retinal pigment epithelium (RPE) cells is a research direction of retinal degeneration diseases, and RPE cell […]

Inflammatory-promoting roles of thymic stromal lymphopoietin and interleukin-4 in allergic conjunctivitis mice

Authors: Ning Chanhui,  Zheng Xiaofen,  Li Bing DOI: 10.3760/cma.j.issn.2095-0160.2017.09.009 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 811-815. Abstract                              [Download PDF] [Read Full Text] Background Researches showed that thymic stromal lymphopoietin (TSLP) is an interleukin-17-like inflammatory factor and plays important roles in the pathogenesis and development of […]

Promoting effects of insulin-like growth factor-1 on proliferation of orbital fibroblasts derived from thyroid associated ophthalmopathy

Authors: Dai Jialing,  He Weimin,  Luo Mengqi DOI: 10.3760/cma.j.issn.2095-0160.2017.09.008 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 805-810. Abstract                              [Download PDF] [Read Full Text] Background Thyroid associated ophthalmopathy (TAO) is an autoimmune disease.Current research on the pathogenesis focuses on common autoantigen.Insulin-like growth factor-1 receptor (IGF-1R) is necessary […]

Inflammation-causing effects and mechanism of natural killer cells in experimental autoimmune uveitis rats

Authors: Li Mohan,  Bao Ning,  Liu Dongwei,  Tao Liming,  Jiang Zhengxuan DOI: 10.3760/cma.j.issn.2095-0160.2017.09.007 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 799-804. Abstract                              [Download PDF] [Read Full Text] Background Experimental autoimmune uveitis (EAU) is a common animal model of uveitis.Natural killer (NK) cells have been confirmed to be a […]

Dynamic expression and mechanism of γδ T cells in the spleen of mouse with experimental autoimmune uveitis

Authors: Wang Beibei,  Tian Qingmei,  Xie Xiaofeng,  Song Jike,  Bi Hongsheng DOI: 10.3760/cma.j.issn.2095-0160.2017.09.006 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 793-798. Abstract                              [Download PDF] [Read Full Text] Background Previous studies showed that the pathogenesis of uveitis is related to γδ T cells.However, it remains unclear that how these […]

Expression and significance of nuclear factor-κB-related proteins in idiopathic orbital inflammatory pseudotumor

Authors: Yang Linqi,  Zhao Pengxiang,  Wu Yanan,  Zhang Xujuan,  Shang Lei,  Liu Mengyu,  Liu Xiao,  Ma Jianmin,  Ma Xuemei DOI: 10.3760/cma.j.issn.2095-0160.2017.09.004 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 786-791. Abstract                              [Download PDF] [Read Full Text] Background Idiopathic orbital inflammatory pseudotumor (IOIP) is a commom orbital disease, with serious eye symptoms and replase […]

Differential expression profile of microRNAs in different types of uveal melanoma

Authors: Liu Yinan,  Shao Lei,  Wei Wenbin DOI: 10.3760/cma.j.issn.2095-0160.2017.09.003 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 778-785. Abstract                               [Download PDF] [Read Full Text] Background Researches showed that microRNA (miRNA) is involved in the pathogenesis and development of many tumors and plays a cancer-suppressing-gene like role or […]

Effect of N-acetylcysteine on the transforming growth factor β1-induced transdifferentiation of retinal pigment epithelial cell to myofibroblast

Authors: Liu Shuai,  Jin Haiying DOI: 10.3760/cma.j.issn.2095-0160.2017.10.008 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 894-901. Abstract                              [Download PDF] [Read Full Text] Background The transdifferentiation of retinal pigment epithelial (RPE) cell to myofibroblast is a central event in the development and progression of proliferative vitreoretinopathy (PVR). […]

Expression of CD147 in laser-induced rat choroidal neovascularization model

Authors: Wang Wenqiu,  Lu Fengqing,  Wang Hong,  Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.007 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 890-893. Abstract                              [Download PDF] [Read Full Text] Background The pathology of choroidal neovascularization (CNV) is not clear.CD147 plays a critical role in angiogenesis through activating […]