Authors: Han Jing, Yan Xiaolong, Xiaoxi Qiao DOI: 10.3760/cma.j.issn.2095-0160.2017.07.002 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 581-585. Abstract [Download PDF] [Read Full Text] Background Studies showed that inflammatory process participates in the pathogenesis and development of diabetic retinopathy targeting retinal vascular endothelial […]
Category: Experimental Science
Inhibitory effects of microRNA-375 on biological behaviour of human retinal capillary endothelial cells induced by hypoxia
Authors: Zhu Jiang, Ren Mei, Xu Zhiguo DOI: 10.3760/cma.j.issn.2095-0160.2017.08.005 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 695-702. Abstract [Download PDF] [Read Full Text] Background Studies showed that microRNA (miR)-375 suppresses the growth, apoptosis, migration and adhesion of tumor cells, and it plays a regulation to the […]
Aggravation effects of JAK-STAT signaling pathway in retinal ischemia reperfusion injury
Authors: Yang Le, Shi Rui, Shen Jiaquan, Xue Yushun DOI: 10.3760/cma.j.issn.2095-0160.2017.08.004 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 690-694. Abstract [Download PDF] [Read Full Text] Background Retinal ischemia reperfusion injury (RIRI) is a common pathological process of many retinal vascular diseases with comprehensive pathogenesis mechanism.Researches showed that […]
Construction of combined lentiviral vectors for rat Slit2 gene RNA interfering and its down-regulation effects on Slit2 gene in rat retinal pigment epithelial cells
Authors: Jiang Shaoqiu, Zhou Xiyuan DOI: 10.3760/cma.j.issn.2095-0160.2017.08.003 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 683-689. Abstract [Download PDF] [Read Full Text] Background Age-related macular degeneration (AMD) is the leading cause of blindness in people over 50 years old, of which 90% cases are caused by […]
Inhibition of adenovirus-mediated recombinant Tum5 gene overexpression on human umbilical vein endothelial cells in physiological status
Authors: Jia Yurong, Yang Wei, Zhang Hong, Zhang Yan, Sun Jing DOI: 10.3760/cma.j.issn.2095-0160.2017.08.002 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 677-682. Abstract [Download PDF] [Read Full Text] Background Tumstatin is the most active endogenous angiogenesis inhibitor, which has a marked inhibitory effect on pathological neovascularization, and Tum5 is […]
Comparison of retinal histomorphology following laser photocoagulation using 577 nm subliminal micropulse laser versus 577 nm laser in pigmented rabbits
Authors: Li Huili, Wang Chunyan, Li Xiaodan, Yu Hai, Fu Yan DOI: 10.3760/cma.j.issn.2095-0160.2017.09.011 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 824-828. Abstract [Download PDF] [Read Full Text] Background Studies showed that 577 nm subliminal micropulse photocoagulation for retinal diseases is more effective and much […]
Mediated effects of endoplasmic reticulum stress on light-induced apoptosis and inflammation of human retinal pigment epithelial cell
Authors: Jiang Wenjing, Zhang Lina, Yu Xiao, Niu Yingjun DOI: 10.3760/cma.j.issn.2095-0160.2017.09.010 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 816-823. Abstract [Download PDF] [Read Full Text] Background The light damage model of retinal pigment epithelium (RPE) cells is a research direction of retinal degeneration diseases, and RPE cell […]
Inflammatory-promoting roles of thymic stromal lymphopoietin and interleukin-4 in allergic conjunctivitis mice
Authors: Ning Chanhui, Zheng Xiaofen, Li Bing DOI: 10.3760/cma.j.issn.2095-0160.2017.09.009 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 811-815. Abstract [Download PDF] [Read Full Text] Background Researches showed that thymic stromal lymphopoietin (TSLP) is an interleukin-17-like inflammatory factor and plays important roles in the pathogenesis and development of […]
Promoting effects of insulin-like growth factor-1 on proliferation of orbital fibroblasts derived from thyroid associated ophthalmopathy
Authors: Dai Jialing, He Weimin, Luo Mengqi DOI: 10.3760/cma.j.issn.2095-0160.2017.09.008 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 805-810. Abstract [Download PDF] [Read Full Text] Background Thyroid associated ophthalmopathy (TAO) is an autoimmune disease.Current research on the pathogenesis focuses on common autoantigen.Insulin-like growth factor-1 receptor (IGF-1R) is necessary […]
Inflammation-causing effects and mechanism of natural killer cells in experimental autoimmune uveitis rats
Authors: Li Mohan, Bao Ning, Liu Dongwei, Tao Liming, Jiang Zhengxuan DOI: 10.3760/cma.j.issn.2095-0160.2017.09.007 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 799-804. Abstract [Download PDF] [Read Full Text] Background Experimental autoimmune uveitis (EAU) is a common animal model of uveitis.Natural killer (NK) cells have been confirmed to be a […]