Authors: Dou Zexia, Ru Yusha, Liu Huijuan, Zeng Xiaoyu, Meng Zhu, Gu Zhongxiu, Zhang Yan, Zhao Shaozhen DOI: 10.3760/cma.j.issn.2095-0160.2017.06.004 Published 2017-06-10 Cite as Chin J Exp Ophthalmol, 2017,35(06): 498-505. Abstract [Download PDF] [Read Full Text] Background Reasearches showed that α-melanocyte-stimulating hormone (α-MSH) inhibits inflammation and ameliorates the ocular surface abnormalities in a scopolamine-induced […]
Category: Experimental Science
Dynamic expression changes of Smad3 and type Ⅰ collagen in sclera of progressive myopia in guinea pigs
Authors: Jiang Bo, Wu Zhangyou, Zhu Zicheng, Hu Wei, Zhan Xin DOI: 10.3760/cma.j.issn.2095-0160.2017.06.003 Published 2017-06-10 Cite as Chin J Exp Ophthalmol, 2017,35(06): 491-497. Abstract [Download PDF] [Read Full Text] Background Sclera remodeling process in axial elongation is one of the main pathological mechanisms of axial myopia progression.Studies confirmed that transforming […]
Dynamic expression of conventional protein kinase C-γ with development of visual cortex and effect of monocular deprivation on it in mice
Authors: Xi Ping, Wang Jing, Han Song, Li Junfa, Fu Tao DOI: 10.3760/cma.j.issn.2095-0160.2017.06.002 Published 2017-06-10 Cite as Chin J Exp Ophthalmol, 2017,35(06): 486-490. Abstract [Download PDF] [Read Full Text] Background Plasticity of visual system is one of the mechanisms of deprivation amblyopia.Our previous study showed that synapsin plays a role […]
Protection of polysaccharides of dendrobium candidum on blood-retinal barrier in diabatic rats and its mechanism
Authors: Li Jingwen, Li Guowen, Lu Jun, Li Chunxia DOI: 10.3760/cma.j.issn.2095-0160.2017.07.008 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 611-616. Abstract [Download PDF] [Read Full Text] Background The pathogenesis of diabetic retinopathy (DR) involves a variety of biological pathways.Recently, inflammation factor has been thought to paly an important […]
Protective effects of tissue factor targeting peptide on human retinal pigment epithelial cell damage induced by blue light
Authors: Li Dandan, Zou Xiulan, Chen Jingxia, Xu Zhe, Yu Yongzhen, Zhou Wenjie, Wang Guanfeng, Rao Benqiang, Zou Yuping DOI: 10.3760/cma.j.issn.2095-0160.2017.07.006 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 603-609. Abstract [Download PDF] [Read Full Text] Background Light-induced retinal damage results in the damage of retinl pigment epithelial (RPE) cells and therefore affects […]
Regulation of high glucose to the expression of Toll-like receptor 4 in retinal ganglion cells and its significance
Authors: Hu Lili, Ai Ming, Yang Hongxia, Jiang Shuanghong DOI: 10.3760/cma.j.issn.2095-0160.2017.07.005 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 597-602. Abstract [Download PDF] [Read Full Text] Background Studies show that retinal neurodegeneration may precede retinal microvascular changes in diabetes mellitus.The apoptosis of retinal ganglion cells (RGCs) is an […]
Photobiomodulation of light emitting diode irradiation on apoptosis of retinal neuronal cells induced by high-glucose
Authors: Zhang Limin, Zhang Fengjiu, Lin Anling, Peng Xiangdong, Yang Jianling, Yu Lingyan, Wang Haiming, Gao Shikai DOI: 10.3760/cma.j.issn.2095-0160.2017.07.004 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 591-596. Abstract [Download PDF] [Read Full Text] Background To study the pathogenesis and management of diabetic retinopathy (DR) has an important clinical significance.With the development […]
Inhibitory effects of apolipoprotein A-Ⅰ on biological behavior and VEGF expression of human retinal epithelial cells in high glucose environment
Authors: Tan Chengye, Shao Jun, Zhuang Miao, Yao Yong DOI: 10.3760/cma.j.issn.2095-0160.2017.07.003 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 586-590. Abstract [Download PDF] [Read Full Text] Background As a main cellular component of retinal microvascular, retinal vascular endothelial cells (RVECs) play critical roles in the occurrence and development […]
Protection effects of metformin on biological behaviour of human vascular endothelial cells under inflammatory conditions
Authors: Han Jing, Yan Xiaolong, Xiaoxi Qiao DOI: 10.3760/cma.j.issn.2095-0160.2017.07.002 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 581-585. Abstract [Download PDF] [Read Full Text] Background Studies showed that inflammatory process participates in the pathogenesis and development of diabetic retinopathy targeting retinal vascular endothelial […]
Inhibitory effects of microRNA-375 on biological behaviour of human retinal capillary endothelial cells induced by hypoxia
Authors: Zhu Jiang, Ren Mei, Xu Zhiguo DOI: 10.3760/cma.j.issn.2095-0160.2017.08.005 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 695-702. Abstract [Download PDF] [Read Full Text] Background Studies showed that microRNA (miR)-375 suppresses the growth, apoptosis, migration and adhesion of tumor cells, and it plays a regulation to the […]