Category: Experimental Science

Dynamic expression and mechanism of γδ T cells in the spleen of mouse with experimental autoimmune uveitis

Authors: Wang Beibei,  Tian Qingmei,  Xie Xiaofeng,  Song Jike,  Bi Hongsheng DOI: 10.3760/cma.j.issn.2095-0160.2017.09.006 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 793-798. Abstract                              [Download PDF] [Read Full Text] Background Previous studies showed that the pathogenesis of uveitis is related to γδ T cells.However, it remains unclear that how these […]

Expression and significance of nuclear factor-κB-related proteins in idiopathic orbital inflammatory pseudotumor

Authors: Yang Linqi,  Zhao Pengxiang,  Wu Yanan,  Zhang Xujuan,  Shang Lei,  Liu Mengyu,  Liu Xiao,  Ma Jianmin,  Ma Xuemei DOI: 10.3760/cma.j.issn.2095-0160.2017.09.004 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 786-791. Abstract                              [Download PDF] [Read Full Text] Background Idiopathic orbital inflammatory pseudotumor (IOIP) is a commom orbital disease, with serious eye symptoms and replase […]

Differential expression profile of microRNAs in different types of uveal melanoma

Authors: Liu Yinan,  Shao Lei,  Wei Wenbin DOI: 10.3760/cma.j.issn.2095-0160.2017.09.003 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 778-785. Abstract                               [Download PDF] [Read Full Text] Background Researches showed that microRNA (miRNA) is involved in the pathogenesis and development of many tumors and plays a cancer-suppressing-gene like role or […]

Effect of N-acetylcysteine on the transforming growth factor β1-induced transdifferentiation of retinal pigment epithelial cell to myofibroblast

Authors: Liu Shuai,  Jin Haiying DOI: 10.3760/cma.j.issn.2095-0160.2017.10.008 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 894-901. Abstract                              [Download PDF] [Read Full Text] Background The transdifferentiation of retinal pigment epithelial (RPE) cell to myofibroblast is a central event in the development and progression of proliferative vitreoretinopathy (PVR). […]

Expression of CD147 in laser-induced rat choroidal neovascularization model

Authors: Wang Wenqiu,  Lu Fengqing,  Wang Hong,  Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.007 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 890-893. Abstract                              [Download PDF] [Read Full Text] Background The pathology of choroidal neovascularization (CNV) is not clear.CD147 plays a critical role in angiogenesis through activating […]

Effect of congenital stationary night blindness on oxygen induced retinal neovascularization by improved Chinese ink perfusion method

Authors: Song Meixia,  Li Shang,  Niu Chao,  Zhang Zuoming DOI: 10.3760/cma.j.issn.2095-0160.2017.10.006 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 885-889. Abstract                               [Download PDF] [Read Full Text] Background Congenital stationary night blindness (CSNB) is a common genetic eye disease.Retinal angiogenesis is rarely obtained in retinal degeneration animal.The effects of CSNB […]

Effect of DNA damage marker γH2AX in the process of oxygen-induced retinal neovascularization

Authors: Li Ruolin,  Chen Nan,  Meng Lili,  Zhu Hong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.005 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 879-884. Abstract                             [Download PDF] [Read Full Text] Background Changes in the concentration of oxygen induced retinal neovascularization and DNA damage repair response.Overexpression of angiogenic factors is […]

Effect of Cathepsin B and vascular endothelial growth factor on the retinal neovascularization induced by hyperoxia

Authors: Wang Wenjuan,  Zhou Guohong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.003 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 873-877. Abstract                               [Download PDF] [Read Full Text] Background Vascular endothelial growth factor (VEGF) plays a key role in the vascular development and neovascularization.Studies have proved that Cathepsin B is related to […]

Promoting effects of macrogol 15 hydroxystearate micelles on corneal absorption of terbinafine hydrochloride

Authors: Zhou Tianyang,  Xia Huiyun,  He Jijun,  Zhang Junjie  DOI: 10.3760/cma.j.issn.2095-0160.2017.11.011 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 1009-1013. Abstract                               [Download PDF] [Read Full Text] Background Macrogol 15 hydroxystearate (HS15) is a novel soft non-ionic surfactant and is widely used to solubilize the poorly soluble drugs due […]

Optical performance of rotation and decentration of Toric intraocular lens implant in Hwey-Lan Liou model eye

Authors: Chai Qiannan,  Zhang Bin,  Geng Yuxin,  Du Yinghua,  Liu Danyan,  Ma Feiyan,  Wei Yuhua DOI: 10.3760/cma.j.issn.2095-0160.2017.11.010 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 1003-1008. Abstract                              [Download PDF] [Read Full Text] Background Cornea astigmatism can be effectively corrected by implanting Toric intraocular lens (IOL) during cataract surgery and therefore improve […]