Authors: Song Meixia, Li Shang, Niu Chao, Zhang Zuoming DOI: 10.3760/cma.j.issn.2095-0160.2017.10.006 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 885-889. Abstract [Download PDF] [Read Full Text] Background Congenital stationary night blindness (CSNB) is a common genetic eye disease.Retinal angiogenesis is rarely obtained in retinal degeneration animal.The effects of CSNB […]
Category: Experimental Science
Effect of DNA damage marker γH2AX in the process of oxygen-induced retinal neovascularization
Authors: Li Ruolin, Chen Nan, Meng Lili, Zhu Hong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.005 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 879-884. Abstract [Download PDF] [Read Full Text] Background Changes in the concentration of oxygen induced retinal neovascularization and DNA damage repair response.Overexpression of angiogenic factors is […]
Effect of Cathepsin B and vascular endothelial growth factor on the retinal neovascularization induced by hyperoxia
Authors: Wang Wenjuan, Zhou Guohong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.003 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 873-877. Abstract [Download PDF] [Read Full Text] Background Vascular endothelial growth factor (VEGF) plays a key role in the vascular development and neovascularization.Studies have proved that Cathepsin B is related to […]
Promoting effects of macrogol 15 hydroxystearate micelles on corneal absorption of terbinafine hydrochloride
Authors: Zhou Tianyang, Xia Huiyun, He Jijun, Zhang Junjie DOI: 10.3760/cma.j.issn.2095-0160.2017.11.011 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 1009-1013. Abstract [Download PDF] [Read Full Text] Background Macrogol 15 hydroxystearate (HS15) is a novel soft non-ionic surfactant and is widely used to solubilize the poorly soluble drugs due […]
Optical performance of rotation and decentration of Toric intraocular lens implant in Hwey-Lan Liou model eye
Authors: Chai Qiannan, Zhang Bin, Geng Yuxin, Du Yinghua, Liu Danyan, Ma Feiyan, Wei Yuhua DOI: 10.3760/cma.j.issn.2095-0160.2017.11.010 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 1003-1008. Abstract [Download PDF] [Read Full Text] Background Cornea astigmatism can be effectively corrected by implanting Toric intraocular lens (IOL) during cataract surgery and therefore improve […]
Study on the relationship between CFTR physiological secretion pathway and intracellular calcium signaling in rabbit cornea epithelium
Authors: Lin Limian, Luo Yiling, Zhou Shiyou DOI: 10.3760/cma.j.issn.2095-0160.2017.11.009 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 998-1002. Abstract [Download PDF] [Read Full Text] Background Researches showed that cystic fibrosis transmembrane conductance regulator protein(CFTR) is a channel secreting anion and water, and it plays an important role […]
The inhibitory effects of baicalein on overexpression of proline hydroxylase 2 in hypoxia-induced retinal glial cells
Authors: Yang Ning, Lu Qiang, Yuan Mengke, Zhang Han, Cui Wei DOI: 10.3760/cma.j.issn.2095-0160.2017.11.007 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 990-996. Abstract [Download PDF] [Read Full Text] Background Proline hydroxylase 2 (PHD2) is a degrading enzyme of hypoxia-inducible factor-1α (HIF-1α) and can regulate the expression of vascular endothelial […]
Feasibility of constructing keratectasia animal model using collagenase type Ⅱ
Authors: Qiao Jing, Li Haili, Song Wenjing, Tang Yun, Rong Bei, Yang Songlin, Wu Yuan, Yan Xiaoming DOI: 10.3760/cma.j.issn.2095-0160.2017.11.006 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 984-989. Abstract [Download PDF] [Read Full Text] Background Keratoconus is a chronic and progressive non-inflammatory ectatic disorder characterized by corneal thinning […]
Inhibitory effects of microRNA-133b on ultraviolet-induced apoptosis of lens epithelial cells and its mechanism
Authors: Li Xiaotong, Qin Yu, Zhao Jiangyue, Min Rui, Zhang Jinsong DOI: 10.3760/cma.j.issn.2095-0160.2017.11.005 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 977-983. Abstract [Download PDF] [Read Full Text] Background Ultraviolet B (UVB) is one of the main causes of cataract formation, and its mechanism is associated with the apoptosis […]
Degeneration of short-wavelength cone cells in rd12 mice
Authors: Li Xia, Zhang Hua, Dai Xufeng, Pang Jijing DOI: 10.3760/cma.j.issn.2095-0160.2017.11.003 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 970-975. Abstract [Download PDF] [Read Full Text] Background Retinitis pigmentosa (RP) is one of the causes of congenital blindness.It is well known that the degeneration process of rod cells […]