Category: 2017, No. 10

The efficiency and safety assessment of Entranster™ nanoparticle carrier for CD25 siRNA transfection in rat cornea

Authors:Qin Qin,  Shi Yunjie,  Zhao Min DOI: 10.3760/cma.j.issn.2095-0160.2016.10.005 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 888-895. Abstract Background Gene transfection is an effective therapeutic avenue to target many kinds of eye diseases.Non-viral vectors with high transfection efficiency, long-term expression, low toxicity and high expression levels are pivotal in gene therapy of corneal disease. Objective […]

Research progress of the spectral-domain optical coherence tomography for glaucoma diagnosis

Authors: Tao Yulin,  Jiang Zhengxuan,  Tao Liming DOI: 10.3760/cma.j.issn.2095-0160.2017.10.022 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 955-960. Abstract Optical coherence tomography (OCT) has the advantage of non-contact, good repeatability and quick to obtain retinal image.With the rapid development of resolution and scanning speed, OCT has been more widely used in the field of ophthalmology.OCT has developed […]

Review on progress of choroidal thickness

Authors: He Lyufu,  Wang Xiaohua,  Wen Xu DOI: 10.3760/cma.j.issn.2095-0160.2017.10.021 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 949-954. Abstract The introduction of optical coherence tomography (OCT) into clinical practice has changed methods of the ophthalmic clinical diagnosis and treatment.With the progression of new technology, OCT has obtained a true, non-invasive optical biopsy of the posterior segment.With advancements […]

Application of optical coherence tomography angiography for diagnosis in fundus diseases

Authors: Yang Jingyuan,  Chen Youxin DOI: 10.3760/cma.j.issn.2095-0160.2017.10.020 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 944-948. Abstract Optical coherence tomography angiography (OCTA) obtains information of retinal and choroidal blood flow by processing the difference between repeated scan of the same voxel.OCTA can be used in fundus diseases because of noninvasive, three-dimensional and high resolution aquisition.OCTA is […]

Role of Hedgehog signaling pathway in the development of retinal cells and pathological angiogenesis

Authors: Liu Meilin,  Di Yu,  Chen Xiaolong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.019 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 940-943. Abstract The pathological growth of retinal cells and ocular pathologic angiogenesis can be seen in a variety of eye diseases, which seriously affect the visual acuity of patients.The Hedgehog signal pathway has been demonstrated to be involved in the […]

Effect of apelin/APJ in retinal vascular diseases

Authors: Chen Li,  Bai Yujing,  Jiang Yanrong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.018 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 936-939. Abstract The G protein-coupled receptor was deorphanized with cloning of the APJ-endogenous ligand apelin, which is an important active peptides.Apelin/APJ system is widely distributed in central nervous system, cardiovascular system, immune system and endocrine system.Therefore, apelin plays important physiological […]

A randomized controlled clinical trial on the effects of wearing orthokeratology and spectacles on ocular peripheral refraction in myopic children

Authors: Wei Shifei,  Li Shiming,  Sun Yunyun,  Kang Mengtian,  Meng Bo,  Ran Anran,  Yan Ran,  Bai Yawen,  Zhuo Chen,  Wang Ningli DOI: 10.3760/cma.j.issn.2095-0160.2017.10.017 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 930-935. Abstract Background It has been reported that orthokeratology has the effects of slowing down myopia progression and axial elongation.However, the affecting mechanism of orthokeratology wearing on ocular peripheral refraction is still not […]

Dynamic changes of 2.8 mm clear corneal incisions architecture with different angles and comparison of safety

Authors: Zhang Ling,  Wang Yuchuan,  Yan Song DOI: 10.3760/cma.j.issn.2095-0160.2017.10.015 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 924-928. Abstract Background In recent years, the relationship between transparent corneal incision and endophthalmitis is attracting more and more attention.Transparent corneal incision configuration become a research hotspot. Objective This study was to analyze dynamic architectural changes of 2.8 mm clear […]

Effects of intravitreal injection of conbercept on vitrectomy for proliferative diabetic retinopathy

Authors: Zeng Guangchuan,  Li Pingping,  Ye Yangjun  DOI: 10.3760/cma.j.issn.2095-0160.2017.10.014 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 920-923. Abstract Background Pars plana vitrectomy (PPV) is the main therapy for advanced stage of proliferative diabetic retinopathy (PDR). Intravitreal injection of anti-vascular endothelial growth factor(VEGF) drug before PPV for PDR has been proved to decrease the occurrence of postoperative […]

Clinical effect of vitreoretinal surgery combined with intravitreal injection of conbercept or ranibizumab on severe proliferative diabetic retinopathy

Authors: Guo Jing,  Chen Song,  Wang Yun,  Liang Xu DOI: 10.3760/cma.j.issn.2095-0160.2017.10.013 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 914-919. Abstract Background Vitreoretinal surgery (VRS) is the main treatment of severe proliferative diabetic retinopathy (PDR), intravitreal injection of anti-VEGF drugs before VRS on severe PDR has been widely used in clinic, but the auxiliary effect of different anti-VEGF […]