Category: Experimental Science

Inhibiting effects of Src kinase inhibitor on TGF-β1 induced epithelial-mesenchymal transition of human RPE cells

Authors: He Jianfeng,  Lyu Lixia,  Luo Junjie,  Li Zongyi,  Shen Junhui,  Xu Guotong,  Gao Furong DOI: 10.3760/cma.j.issn.2095-0160.2018.01.002 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 5-11. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the inhibiting effect of CGP77675 (CGP), a Src inhibitor, on epithelial-mesenchymal transition (EMT) of human retinal […]

Dynamic observation of ocular surface in ovariectomized cynomolgus monkey

Authors: Li Lei,  Zhang Xiaofeng,  Li Mengmeng,  Que Lijuan,  Li Chang DOI: 10.3760/cma.j.issn.2095-0160.2018.02.008 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 113-118. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the feasibility of ovariectomized cynomolgus monkey as an animal model of postmenopausal dry eye. Methods Six healthy adult […]

Biophysical characteristics of genipin-crosslinked amniotic membrane bio-scaffold

Authors: Yin Yanfeng,  Yang Liu,  Tu Qiufen,  Lyu Sha,  Guan Zheng,  Su Wenjun,  Li Yunchuan,  Li Lan DOI: 10.3760/cma.j.issn.2095-0160.2018.02.007 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 107-112. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the characteristics and feasibility of genipin-crosslinked amniotic membrane(AM) as bio-scaffold. Methods […]

Promoting repair effects of chitosan/gelatin electrospinning membrane implantation on rabbit conjunctival injury

Authors: Zheng Yuqiang,  Wang Zhuoshi,  Xu Ling,  Wang Liansong,  He Wei DOI: 10.3760/cma.j.issn.2095-0160.2018.02.006 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 102-106. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the promoting repair effects of chitosan/gelatin electrospinning membrane implantation on conjunctival injury. Methods Chitosan/gelatin electrospinning membrane was prepared […]

Enhancement of scleral biomechanics and safety following minimally invasive riboflavin-ultraviolet A collagen crosslinking in rabbits

Authors: Wang Hongyan,  Xiao Bo,  Chu Yanhua,  Han Quanhong DOI: 10.3760/cma.j.issn.2095-0160.2018.02.005 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 96-101. Abstract                               [Download PDF] [Read Full Text] Objective To evaluate the enhancing effects of scleral biomechanics and safety of collagen crosslinking by using minimally invasive riboflavin and ultraviolet A. […]

Neuroprotective effects of tianmagouteng decoction on retinal ganglion cells in optic nerve crush model

Authors: Li Yujie,  Ma Ke,  Zhang Haijuan,  Wang Haiyan DOI: 10.3760/cma.j.issn.2095-0160.2018.02.004 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 91-95. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the neuroprotective effect and antioxidation mechanism of tianmagouteng decoction on retinal ganglion cells (RGCs) in optic nerve crush model. […]

Inhibitory effects of apolipoprotein M on inflammatory factors induced by high glucose in human retinal vascular endothelial cells

Authors: Tang Huan,  Luo Guanghua,  Yao Shuang,  Wang Min,  Pan Lili,  Yu Miaomei,  Yu Yang,  Liu Yao DOI: 10.3760/cma.j.issn.2095-0160.2018.03.008 Published 2018-03-10 Cite as Chin J Exp Ophthalmol, 2018,36(3): 194-198. Abstract                               [Download PDF] [Read Full Text] Objective To observe the expressing changes of apolipoprotein M (ApoM), tumor necrosis factor-α (TNF-α) and monocyte chemoattractant protein-1 […]

Role of autophagy in angiogenesis of retinal vascular endothelial cells under hypoxia condition

Authors: Li Rong,  Du Junhui,  Yao Yang,  Yu Zhaoxiang,  Fan Zhuo,  Chang Weiping DOI: 10.3760/cma.j.issn.2095-0160.2018.03.006 Published 2018-03-10 Cite as Chin J Exp Ophthalmol, 2018,36(3): 187-193. Abstract                               [Download PDF] [Read Full Text] Objective To study the role of autophagy in proliferation, migration and tube formation of retinal vascular endothelial cells (RVECs) under […]

Regulation of Krüppel-like factor 6 via activating transcription factor 4 pathway to apoptosis of human lens epithelial cells

Authors: Tian Fang,  Zhao Jinzhi,  Teng He,  Huang Liangyu,  Liu Xun,  Su Ruihong,  Gao Meizi,  Zhang Xiaomin,  Li Xiaorong,  Dong Lijie,  Zhang Hong DOI: 10.3760/cma.j.issn.2095-0160.2018.03.005 Published 2018-03-10 Cite as Chin J Exp Ophthalmol, 2018,36(3): 181-186. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the regulating effects of Krüppel-like factor 6 (KLF6) on the apoptosis of […]

Optical imaging quality change of multifocal intraocular lens following Nd: YAG laser damage

Authors:  Sun Yanxiu,  Hao Yansheng,  Xie Jiangbing,  Wang Zhao,  Guo Shuyan,  Zhou Jian,  Tian Yun DOI: 10.3760/cma.j.issn.2095-0160.2018.03.004 Published 2018-03-10 Cite as Chin J Exp Ophthalmol, 2018,36(3): 176-180. Abstract                               [Download PDF] [Read Full Text] Objective To study the optical imaging quality of multifocal intraocular lens (IOL) following Nd: YAG laser damage. Methods Three […]