Authors: Li Dan, Liu Gaoqin, Chen Lei, Wang Mengjiao, Lu Peirong DOI: 10.3760/cma.j.issn.2095-0160.2018.01.008 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 34-39. Abstract [Download PDF] [Read Full Text] Objective This study was to investigate the role of recombinant human platelet derived growth factor-BB(rhPDGF-BB) in the proliferation and migration of […]
Category: Experimental Science
Inhibitory effects of Genistein on hyperoxia-induced retinal neovascularization
Authors: He Ronghua, Zhou Guohong, Kong Li, Li Chenyu DOI: 10.3760/cma.j.issn.2095-0160.2018.01.007 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 29-33. Abstract [Download PDF] [Read Full Text] Objective To investigate the effect of Genistein, a tyrosinase inhibitor, on retinal neovascularization in mice. Methods Thirty-six 7-day-old C57BL/6J mice were randomly […]
Induction of chorioretinopathy by adrenaline injection in different strains of rabbits
Authors: Yan Weiming, Chen Tao, Long Pan, Ren Ze, Li Xiangqian, Sun Kai, Ma Yifei, Wang Xiaocheng, Xue Junhui, Zhang Zuoming DOI: 10.3760/cma.j.issn.2095-0160.2018.01.005 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 23-27. Abstract [Download PDF] [Read Full Text] Objective To establish a central serous chorioretinopathy(CSC) model on different strains of rabbits by intravenous injection […]
The promoting effects of SNAI1 activating matrix metalloproteinase on choroidal neovascularization under hypoxia
Authors: Sun Jiaxing, Dou Guorui, Chang Tianfang, Li Manhong, Yang Ziyan, Yan Xianchun, Liu Yuan, Han Hua, Wang Yusheng DOI: 10.3760/cma.j.issn.2095-0160.2018.01.004 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 16-22. Abstract [Download PDF] [Read Full Text] Objective To investigate whether vascular endothelial cells in choroidal neovascularization whether hypoxia condition can up-regulate SNAI1 and […]
Neuroprotective effects of brimonidine on retinal ganglion cells induced by oxidative stress mitochondrial dysfunction
Authors: Wang Lu, Lin Binwu, Wang Yan, Pang Long DOI: 10.3760/cma.j.issn.2095-0160.2018.01.003 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 12-15. Abstract [Download PDF] [Read Full Text] Objective To explore whether brimonidine has a protective effect on retinal ganglion cells (RGCs) through improving mitochondrial function under the oxidative stress. […]
Inhibiting effects of Src kinase inhibitor on TGF-β1 induced epithelial-mesenchymal transition of human RPE cells
Authors: He Jianfeng, Lyu Lixia, Luo Junjie, Li Zongyi, Shen Junhui, Xu Guotong, Gao Furong DOI: 10.3760/cma.j.issn.2095-0160.2018.01.002 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 5-11. Abstract [Download PDF] [Read Full Text] Objective To investigate the inhibiting effect of CGP77675 (CGP), a Src inhibitor, on epithelial-mesenchymal transition (EMT) of human retinal […]
Dynamic observation of ocular surface in ovariectomized cynomolgus monkey
Authors: Li Lei, Zhang Xiaofeng, Li Mengmeng, Que Lijuan, Li Chang DOI: 10.3760/cma.j.issn.2095-0160.2018.02.008 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 113-118. Abstract [Download PDF] [Read Full Text] Objective To investigate the feasibility of ovariectomized cynomolgus monkey as an animal model of postmenopausal dry eye. Methods Six healthy adult […]
Biophysical characteristics of genipin-crosslinked amniotic membrane bio-scaffold
Authors: Yin Yanfeng, Yang Liu, Tu Qiufen, Lyu Sha, Guan Zheng, Su Wenjun, Li Yunchuan, Li Lan DOI: 10.3760/cma.j.issn.2095-0160.2018.02.007 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 107-112. Abstract [Download PDF] [Read Full Text] Objective To investigate the characteristics and feasibility of genipin-crosslinked amniotic membrane(AM) as bio-scaffold. Methods […]
Promoting repair effects of chitosan/gelatin electrospinning membrane implantation on rabbit conjunctival injury
Authors: Zheng Yuqiang, Wang Zhuoshi, Xu Ling, Wang Liansong, He Wei DOI: 10.3760/cma.j.issn.2095-0160.2018.02.006 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 102-106. Abstract [Download PDF] [Read Full Text] Objective To investigate the promoting repair effects of chitosan/gelatin electrospinning membrane implantation on conjunctival injury. Methods Chitosan/gelatin electrospinning membrane was prepared […]
Enhancement of scleral biomechanics and safety following minimally invasive riboflavin-ultraviolet A collagen crosslinking in rabbits
Authors: Wang Hongyan, Xiao Bo, Chu Yanhua, Han Quanhong DOI: 10.3760/cma.j.issn.2095-0160.2018.02.005 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 96-101. Abstract [Download PDF] [Read Full Text] Objective To evaluate the enhancing effects of scleral biomechanics and safety of collagen crosslinking by using minimally invasive riboflavin and ultraviolet A. […]