Authors: Qiao Jing, Li Haili, Song Wenjing, Tang Yun, Rong Bei, Yang Songlin, Wu Yuan, Yan Xiaoming DOI: 10.3760/cma.j.issn.2095-0160.2017.11.006 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 984-989. Abstract [Download PDF] [Read Full Text] Background Keratoconus is a chronic and progressive non-inflammatory ectatic disorder characterized by corneal thinning […]
Category: Experimental Science
Inhibitory effects of microRNA-133b on ultraviolet-induced apoptosis of lens epithelial cells and its mechanism
Authors: Li Xiaotong, Qin Yu, Zhao Jiangyue, Min Rui, Zhang Jinsong DOI: 10.3760/cma.j.issn.2095-0160.2017.11.005 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 977-983. Abstract [Download PDF] [Read Full Text] Background Ultraviolet B (UVB) is one of the main causes of cataract formation, and its mechanism is associated with the apoptosis […]
Degeneration of short-wavelength cone cells in rd12 mice
Authors: Li Xia, Zhang Hua, Dai Xufeng, Pang Jijing DOI: 10.3760/cma.j.issn.2095-0160.2017.11.003 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 970-975. Abstract [Download PDF] [Read Full Text] Background Retinitis pigmentosa (RP) is one of the causes of congenital blindness.It is well known that the degeneration process of rod cells […]
Inhibitory effects of bevacizumab on corneal neovascularization and scarring in mice with herpes simplex keratitis
Authors: Zhou Hongwei, Wang Tongsong, Zhang Songmei, Xie Lixin DOI: 10.3760/cma.j.issn.2095-0160.2017.12.007 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1085-1091. Abstract [Download PDF] [Read Full Text] Background Corneal neovascularization and inflammation occur in herpes simplex keratitis (HSK). Aciclovir (ACV) is an antiviral medication which is primarily used for […]
Lowing-intraocular pressure and improving aqueous humor dynamic effects of qingguangan drug granules in spontaneous glaucoma mice
Authors: Long Da, Zhou Yasha, Li Ping, Liu Jiaqi, Peng Jun, Tan Hanyu, Peng Qinghua DOI: 10.3760/cma.j.issn.2095-0160.2017.12.006 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1079-1084. Abstract [Download PDF] [Read Full Text] Background Researches showed that the increase of intraocular pressure (IOP) in glaucomatous eye is associated with the increasing resistance […]
Expression changes and significance of ATP-binding cassette transporter B5 in pterygium
Authors: Cai Yan, Zhao Xudong, Wang Wei, Yin Na, Wang Huixian, Gao Xiaowei DOI: 10.3760/cma.j.issn.2095-0160.2017.12.004 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1073-1077. Abstract [Download PDF] [Read Full Text] Background Limbal stem cells (LSCs) deficiency leads to many ocular surface diseases, such as pterygium and so on.ATP-binding cassette transporter […]
Regulation of sericin on retinal endoplasmic reticulum stress specific caspase-12 dependent pathway and inhibition on apoptosis in diabetic rat
Authors: Dong Zhijun, Yang Nan, Chen Zhihong, Yang Fan, Yu Hongfei, Dong Weili, Zhang Tiemin DOI: 10.3760/cma.j.issn.2095-0160.2017.12.003 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1067-1072. Abstract [Download PDF] [Read Full Text] Background Endoplasmic reticulum stress (ERS) specific caspase-12 dependent pathway plays a key role in cell apoptosis, and apoptosis is […]
Activation of retinal and optic nerve microglia following optic nerve crush in rats
Authors: Nie Zuqing, Zhang Qiong, Cao Xia DOI: 10.3760/cma.j.issn.2095-0160.2017.12.002 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1060-1066. Abstract [Download PDF] [Read Full Text] Background Traumatic optic neuropathy (TON) is an acute injury of the optic nerve secondary to trauma.As an important immune cell, microglia is involved […]
The effects of recombinant human platelet derived growth factor-BB on biological behaviours of human retinal vascular endothelial cells
Authors: Li Dan, Liu Gaoqin, Chen Lei, Wang Mengjiao, Lu Peirong DOI: 10.3760/cma.j.issn.2095-0160.2018.01.008 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 34-39. Abstract [Download PDF] [Read Full Text] Objective This study was to investigate the role of recombinant human platelet derived growth factor-BB(rhPDGF-BB) in the proliferation and migration of […]
Inhibitory effects of Genistein on hyperoxia-induced retinal neovascularization
Authors: He Ronghua, Zhou Guohong, Kong Li, Li Chenyu DOI: 10.3760/cma.j.issn.2095-0160.2018.01.007 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 29-33. Abstract [Download PDF] [Read Full Text] Objective To investigate the effect of Genistein, a tyrosinase inhibitor, on retinal neovascularization in mice. Methods Thirty-six 7-day-old C57BL/6J mice were randomly […]