Authors: Sun Ruizhu, Zhang Shaodan, Liang Yuanbo DOI: 10.3760/cma.j.issn.2095-0160.2016.04.019 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 375-379. Abstract [Download PDF] [Read Full Text] Glaucoma is a group of neurodegenerative disease characterized by progressive retinal ganglion cells (RGCs) death and visual field defect.Although its pathological mechanism […]
Category: Review
Research progress of vascular endothelial growth factor inhibitor in the treatment of corneal neovascularization
Authors: Lin Tianlan, Zhou Shanbi DOI: 10.3760/cma.j.issn.2095-0160.2016.04.018 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 371-374. Abstract [Download PDF] [Read Full Text] Normal cornea is avascular, fully transparent organization, which is important to the eye refraction.However, many eye diseases can destroy the anti-angiogenic factor and […]
Application of zebrafish in ophthalmology and vision research: history and current progress
Authors: Chen Xueli, Jing Yang, Zhang Qi DOI: 10.3760/cma.j.issn.2095-0160.2016.04.017 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 368-370. Abstract [Download PDF] [Read Full Text] In recent years, zebrafish has become ideal animal models of human disease with its unique characteristics, such as small body, fecundity, fast […]
The mechanism and clinical features of paraneoplastic retinopathy
Authors: Yang Lizhu, Sui Ruifang DOI: 10.3760/cma.j.issn.2095-0160.2016.05.018 Published 2016-05-10 Cite as Chin J Exp Ophthalmol, 2016,34(5): 476-480. Abstract [Download PDF] [Read Full Text] Paraneoplastic retinopathy (PR) is a rare form of paraneoplastic syndrome, it occurs when autoantibodies of neoplasms cross-react with autoantigens in normal retina.PR includes carcinoma-associated […]
Progress on Nrf2 pathway in diabetic retinopathy
Authors: Zhang Siyuan, Lyu Hongbin DOI: 10.3760/cma.j.issn.2095-0160.2016.05.017 Published 2016-05-10 Cite as Chin J Exp Ophthalmol, 2016,34(5): 471-475. Abstract [Download PDF] [Read Full Text] Diabetic retinopathy (DR) is a serious complication of diabetes mellitus, which leads to vision loss or even blindness.Nuclear factor erythroid 2-related factor 2 […]
Current advances on the efflux protein in ocular drug delivery
Authors: Liu Jinkun, Cheng Lingyun DOI: 10.3760/cma.j.issn.2095-0160.2016.05.016 Published 2016-05-10 Cite as Chin J Exp Ophthalmol, 2016,34(5): 466-470. Abstract [Download PDF] [Read Full Text] Efflux protein is an active transport protein family located on cell membranes of various human tissues, including ocular tissues.Efflux […]
Progress in developing a sodium iodate-induced retinitis pigmentosa animal model
Authors: Fan Meihua, Chen Yongxiong DOI: 10.3760/cma.j.issn.2095-0160.2016.09.018 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 860-864. Abstract [Download PDF] [Read Full Text] Retinitis pigmentosa (RP) is a group of clinically and genetically heterogeneous retinal degenerative hereditary diseases that cause severe vision impairment […]
Advances of research on endogenous retinal stem cells
Authors: Zhu Ruilin, Yang Liu DOI: 10.3760/cma.j.issn.2095-0160.2016.09.017 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 855-859. Abstract [Download PDF] [Read Full Text] The retinal neurons can not repair or regenerate once they are injured.Repairing the injured neurons by stem cell therapy is a hotspot in current […]
Advance in methods of induced-embryonic stem cell differentiation to retinal cells
Authors: Zhao Yongji, Pang Li, You Zhipeng DOI: 10.3760/cma.j.issn.2095-0160.2016.09.016 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 851-854. Abstract [Download PDF] [Read Full Text] Retinal degenerative disease is the leading cause of visual loss, the mechanism is not clear and has no effective […]
Postoperative tear dysfunction of LASIK and SMILE
Authors: Li Meiyan, Zhou Xingtao DOI: 10.3760/cma.j.issn.2095-0160.2016.09.015 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 847-850. Abstract [Download PDF] [Read Full Text] Tear dysfunction was considered as abnormalities of tear film composition that include the presence of pro-inflammatory cytokines.Recent studies indicated that altered tear composition caused […]