Evaluation of the effect of Toric design orthokeratology on myopia in adolescents with mild and moderate astigmatism

Authors: Ma Yajuan,  Gao Jianbo,  Xiao Wei,  Chen Linxiu,  Xu Wen
DOI: 10.3760/cma.j.cn115989-20190311-00111
Published 2021-12-10
Cite asChin J Exp Ophthalmol, 2021, 39(12): 1065-1069.

Abstract

Objective

To evaluate the clinical effect of Toric design orthokeratology in myopic teenagers with mild-to-moderate astigmatism.

Methods

A non-randomized controlled clinical study was conducted.Eighty juvenile myopia patients (160 eyes) diagnosed with mild to moderate astigmatism with myopia after mydriatic computer optometry and received the treatment of orthokeratology at Zhejiang Rongjun Hospital from January 2016 to June 2017 were enrolled.The patients were divided into regular spherical design orthokeratology group and Toric design orthokeratology group, with 80 eyes (40 cases) in each group.The patients wore orthokeratology for 8 to 10 hours every night and were re-examined at 1 day, 1 week and 1, 3, 6, 12 and 18 months after wearing, respectively.The visual acuity, refraction, corneal health status and central deviation of the treatment area in the corneal topography map were measured and recorded during the 18-month treatment.The complications during treatment were recorded.After 12-month wearing, the uncorrected visual acuity and the center deviation of the treatment area were compared between the two groups.After 18-month wearing, patients in the two groups stopped wearing the orthokeratology lens for 1 month, and then the refraction examination, IOLMaster and corneal topography were performed to compare the spherical equivalent, axial length and degree of astigmatism.This study protocol adhered to the Declaration of Helsinki and was approved by an Ethics Committee of Zhejiang Rongjun Hospital (No.2020-10). Written informed consent was obtained from guardians prior to any medical examination.

Results

After 12-month wearing, the center deviation of the shaping treatment area was (0.86±0.23)mm in the Toric design orthokeratology group, which was significantly lower than (1.16±0.44)mm in the regular spherical design orthokeratology group (t=5.404, P<0.001). After 12-month wearing, the uncorrected visual acuity was (0.03±0.08) LogMAR in the Toric design orthokeratology group, which was significantly higher than (0.09±0.10) LogMAR in the regular spherical design orthokeratology group (t=2.963, P=0.004). The spherical equivalent and the axial length of Toric design orthokeratology group were significantly smaller than those of the regular spherical design orthokeratology group (t=2.542, 2.107; both at P<0.05), and there was no statistically significant difference in the degree of astigmatism between the two groups (t=0.821, P=0.413). During the 18-month follow-up, the adverse reaction, punctate corneal epithelial opacity, occurred in 18 eyes.The incidence of adverse effect was 6.26%(5/80) in the Toric design orthokeratology group, which was significantly lower than the 16.25% (13/80) in the regular spherical design orthokeratology group (χ2=3.897, P=0.048).

Conclusions

The Toric design orthokeratology shows better efficacy in myopia control as well as reducing the adverse reaction rate in juvenile myopia, and it can better solve the deviation in corneal shaping in the use of regular spherical design orthokeratology.

Key words:

Myopia, juvenile/therapy; Astigmatism/therapy; Orthokeratologic procedure; Treatment outcome; Toric design

Contributor Information

Ma Yajuan

Department of Ophthalmology, Zhejiang Rongjun Hospital, Jiaxing 314000, China

Gao Jianbo

Department of Ophthalmology, Zhejiang Rongjun Hospital, Jiaxing 314000, China

Xiao Wei

Department of Ophthalmology, Zhejiang Rongjun Hospital, Jiaxing 314000, China

Chen Linxiu

Department of Ophthalmology, Zhejiang Rongjun Hospital, Jiaxing 314000, China

Xu Wen

Eye Center, Affiliated Second Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China

(Read 19 times, 1 visits today)
Updated: December 21, 2021 — 6:54 am