Stability of anterior chamber after implantable collamer lens V4c implantation for one year in moderate and high myopic eyes

Authors: Cheng Lei,  Zhu Ran,  Song Chao,  Yuan Ping,  Tan Yue,  Wei Mei
DOI: 10.3760/cma.j.cn115989-20190413-00180
Published 2021-12-10
Cite asChin J Exp Ophthalmol, 2021, 39(12): 1059-1064.

Abstract

Objective

To investigate the stability of anterior chamber following implantable collamer lens (ICL) V4c implantation for one year in moderate and high myopic eyes.

Methods

An observational case series study was conducted.Medical data of 19 patients (37 eyes) who received ICL V4c implantation in Xuzhou First People’s Hospital from March 2016 to October 2017 were collected.The patients were 20 to 29 years old, with the preoperative spherical equivalent (SE) of -5.875 to -15.750 D, with an average of (-9.743±3.220)D.All eyes were followed up for one year, and the changes of visual acuity, SE and intraocular pressure were observed.Pentacam anterior eye segment analyzer was used to measure the anterior chamber depth (ACD), anterior chamber volume (ACV) and anterior chamber angle (ACA) before operation and at 1 month, 6 months and 1 year after operation, and to evaluate the vaults of the ICL V4c at different time points after implantation.This study protocol adhered to the Declaration of Helsinki and was approved by an Ethics Committee of Xuzhou First People’s Hospital (No.xxy11[2015]-XJS-004). Written informed consent was obtained from each subject.

Results

There were statistically significant differences in visual acuity between before and after operation (F=5.057, P=0.007), and the one-year postoperative uncorrected visual acuity (UCVA) was significantly better than the best corrected visual acuity (BCVA) before operation (P<0.05). There were no significant differences in SE and intraocular pressure among different time points (F=1.294, 1.302; both at P>0.05). There were significant differences in ACD, ACV and ACA among different time points (F=44.811, 889.971, 196.096; all at P<0.001). ACD, ACV and ACA at 1 month, 6 months and 1 year after operation were significantly lower than those before operation (all at P<0.001). There was a significant difference in the 1-month, 6-month and 1-year postoperative ICL vault (F=7.256, P=0.001). The ICL vault at 1 year after operation was (433.784±168.550)μm, which was significantly decreased in comparison with (484.860±183.634)μm at 1 month and (464.351±170.167)μm at 6 months after operation (P=0.006, 0.041).

Conclusions

The anterior chamber is stable in one year after ICL V4c implantation, and the UCVA is better than preoperative BCVA.ICL V4c is safe and effective for moderate and high myopia.

Key words:

Myopia; Biometry; Anterior chamber/structure; Implantable collamer lens; Pentacam anterior segment analyzer

Contributor Information

Cheng Lei

Department of Ophthalmology, Xuzhou First People’s Hospital, Xuzhou Eye Institute, Xuzhou 221002, China

Zhu Ran

Department of Ophthalmology, Xuzhou First People’s Hospital, Xuzhou Eye Institute, Xuzhou 221002, China

Song Chao

Department of Ophthalmology, Xuzhou First People’s Hospital, Xuzhou Eye Institute, Xuzhou 221002, China

Yuan Ping

Department of Ophthalmology, Xuzhou First People’s Hospital, Xuzhou Eye Institute, Xuzhou 221002, China

Tan Yue

Department of Ophthalmology, Xuzhou First People’s Hospital, Xuzhou Eye Institute, Xuzhou 221002, China

Wei Mei

Department of Ophthalmology, Xuzhou First People’s Hospital, Xuzhou Eye Institute, Xuzhou 221002, China

Intraocular corrective lens implantation

Placed in the ejector, the intraocular corrective lens (ICL) was pushed into the anterior chamber from the main incision and unfolded naturally. Then the four loops of ICL were adjusted to the posterior surface of the iris and fixed at the ciliary sulcus, and the residual viscoelastics was rinsed out of the anterior chamber. The incision was closed, and the operation was finished.

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Updated: December 21, 2021 — 7:41 am