Progress in diagnosis and treatment of retinal vasoproliferative tumor

Authors: Sun Gongpeng,  Chen Changzheng
DOI: 10.3760/cma.j.cn115989-20200712-00488
Published 2023-07-10
Cite as Chin J Exp Ophthalmol, 2023, 41(7): 693-696.

Abstract                              [Download PDF] [Read Full Text]

Retinal vasoproliferative tumor (RVPT) is a rare benign glial proliferative tumor of unknown origin.The fundus is typically characterized by yellow or pink tumor-like lesions of the retina around the inferior temporal region, often accompanied by subretinal fluid, exudation, epiretinal membrane and other complications.Typical RVPT showed high fluorescence on fundus fluorescein angiography, diffuse leakage in venous phase and late stage, uneven middle or high reflection signal on B-ultrasound, and it was not difficult to diagnose combined with fundus changes.Atypical RVPT should be differentiated from retinal capillary hemangioma caused by von Hippel-Lindau disease, Coats disease and familial exudative vitreoretinopathy.The pathogenesis of RVPT is unclear, but histopathology shows that it may be the reactive proliferation of glial cells.At present, there is no unified treatment plan for RVPT, mainly cryotherapy, laser photocoagulation, local radiotherapy, transpupillary thermal therapy or photodynamic therapy for tumor.For patients with vitreous hemorrhage, vitreoretinal surgery is feasible.This article reviewed the clinical features, diagnosis and differential diagnosis, pathology and pathogenesis, and treatment progress of RVPT.

Key words:

Retinal neoplasms; Retinal vasoproliferative tumor; Diagnosis; Treatment; Clinical manifestation

Contributor Information

Sun Gongpeng

Eye Center, Renmin Hospital of Wuhan University, Wuhan 430060, China

Chen Changzheng

Eye Center, Renmin Hospital of Wuhan University, Wuhan 430060, China

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