Research advancement on necroptosis in retinal cell death

Authors: Lu Bing,  Sun Xiaodong

DOI: 10.3760/cma.j.issn.2095-0160.2016.01.018
Published 2016-01-10
Cite as Chin J Exp Ophthalmol, 2016,34(1): 85-88.

Abstract

Retinal pigment epithelium cells, retinal ganglial cells and photoreceptor cells play vital roles in maintaining the function of retina and choroid.Retinal cell death is the main cause of vision loss in ocular diseases.Necroptosis is a newly found way of programmed cell death.This article presented the mechanism of necroptosis and its research progess in different retinal diseases such as age-related macular degeneration and retinal detachment, which may provide new approaches for retinal diseases treatment.

Key words:

Retinal cells; Necroptosis; Retinal diseases

Contributor Information

Lu Bing
Department of Ophthalmology, Shanghai First People’s Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200080, China
Sun Xiaodong
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