Research progress of intraocular pressure and its related influencing factors in children

Authors: Han Fang,  Wang Yan
DOI: 10.3760/cma.j.cn115989-20200811-00581
Published 2022-04-10
Cite asChin J Exp Ophthalmol, 2022, 40(4): 351-356.

Abstract

Glaucoma is an irreversible cause of blindness, and elevated intraocular pressure (IOP) is an important risk factor for it.There is no clearly defined value of ocular hypertension in children, thus the accurate evaluation of IOP in children and understanding of its influencing factors are of great significance for the timely detection of ocular hypertension in children and the prevention of childhood glaucoma.Different measuring instruments and principles, as well as differences in ocular structures between children and adults, lead to the various sensitivity and reliability of the measurement.Many studies have shown that there are many factors affecting IOP in children, the main influencing factors of which are central corneal thickness, age, race, region, gender, corneal biomechanics, and so on.Obesity, blood pressure, and the use of anesthetics may also have influences on IOP in children.The possible relationship between IOP and refractive state in children is still controversial.For children with high myopia and the tendency to develop high myopia, their IOP should be monitored.Clinical diagnosis of children with ocular hypertension should be cautious, whether to carry out clinical intervention depends on the results of standardized testing and long-term follow-up.At present, accurate assessment and measurement of IOP in children to determine the timing of early warning of ocular hypertension is still the focus of research.Recent progress in IOP and its related influencing factors in children were reviewed in this article.

Key words:

Glaucoma; Ocular hypertension; Intraocular pressure; Children; Measurement; Influencing factors

Contributor Information

Han Fang

Clinical College of Ophthalmology, Tianjin Medical University, Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Tianjin 300020, China

Han Fang is now working at Department of Ophthalmology, The First People’s Hospital of Yunnan Province, Kunming 650032, China

Wang Yan

Clinical College of Ophthalmology, Tianjin Medical University, Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Tianjin 300020, China

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