Research status and issues of severity grading and staging of thyroid-associated ophthalmopathy

Authors: Ou Luyu,  He Weimin,  Wang Yujiao
DOI: 10.3760/cma.j.cn115989-20190526-00233
Published 2022-11-10
Cite asChin J Exp Ophthalmol, 2022, 40(11): 1114-1118.

Abstract                              [View PDF] [Read Full Text]

Thyroid-associated ophthalmopathy (TAO) is a common orbital disease in the adults, which leads to a series of ocular symptoms and signs, seriously affecting the visual function and life quality of patients.Grasping the disease progression accurately and evaluating the severity and activity of TAO objectively play a crucial role in improving the management and prognosis of TAO patients.Grading and staging methods of TAO have been constantly improved.In the descriptive evaluation of subjective symptoms and signs of TAO, four international grading and staging systems with similarities and different focuses, namely, NOSPECS, CAS, VISA and EUGOGO, have been proposed successively.In recent years, with the rapid development of science and technology, objective evaluation methods such as imaging technology and laboratory examination have played an important role in the grading and staging of TAO.Among them, the application of orbital CT and MRI has made a great breakthrough in quantitative analysis of the disease.Continuous summary of grading and staging methods of TAO can contribute to the guidance for improving diagnosis, treatment and prognosis of TAO.

Key words:

Thyroid-associated ophthalmopathy; Severity; Activity; Imaging

Contributor Information

Ou Luyu

Department of Ophthalmology, West China Hospital of Sichuan University, Chengdu 610041, China

He Weimin

Department of Ophthalmology, West China Hospital of Sichuan University, Chengdu 610041, China

Wang Yujiao

Department of Ophthalmology, West China Hospital of Sichuan University, Chengdu 610041, China

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