Research status of molecularly imprinted hydrogel drug-loaded contact lenses

Authors: Xu Jiangning,  Zhou Tong
DOI: 10.3760/cma.j.cn115989-20190430-00204
Published 2022-07-10
Cite asChin J Exp Ophthalmol, 2022, 40(7): 685-689.

Abstract                                       [View PDF] [Read Full Text]

Traditional ophthalmic pharmaceutical preparations are mostly eye drops or eye ointments, which have the disadvantages of low efficiency and poor patient compliance in application.Drug-loaded contact lenses can overcome these shortcomings and have attracted much attention.Improving drug loading capacity and enhancing sustained-release performance of drug-loaded contact lenses are the main focus of research and development.In recent years, drug-loaded contact lenses made of molecularly imprinted hydrogel can significantly improve drug loading capacity and sustained-release performance, and have been widely studied.The application status of molecularly imprinted hydrogel drug-loaded contact lenses in the delivery of ophthalmic drugs, as well as the effects of various factors on drug loading capacity and sustained-release performance were reviewed in this article.

Key words:

Contact lenses; Molecular imprinting technology; Hydrogel; Drug release

Contributor Information

Xu Jiangning

Chongqing Medical and Pharmaceutical College, Chongqing 401331, China

Zhou Tong

Chongqing Medical and Pharmaceutical College, Chongqing 401331, China

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