Category: 2022, No. 07

Expert consensus on repeated low-level red-light as an alternative treatment for childhood myopia (2022)

Author: Expert workgroup of expert consensus on repeated low-level red-light as an alternative treatment for childhood myopia (2022) DOI: 10.3760/cma.j.cn115989-20220616-00279 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 599-603. Abstract Repeated low-level red-light (RLRL) therapy has been adopted into research and practice on childhood myopia control nationwide.Preliminary clinical evidence showed that RLRL has some […]

Critical guiding role of OCT angiography in long-term treatment and follow-up of neovascular AMD

Authors: Bo Qiyu,  Sun Xiaodong DOI: 10.3760/cma.j.cn115989-20220617-00282 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 604-608. Abstract The pathogenesis of neovascular age-related macular degeneration (nAMD) is complex and macular neovascularization (MNV), a key pathogenic factor in nAMD, is prone to recurrence.Vitreous injection of anti-VEGF drugs is the main therapy of nAMD.In recent years, a […]

Inhibitory effect of vorinostat encapsulated hydroxypropyl-β-cyclodextrin eye drops on corneal neovascularization induced by alkali burns in mouse

Authors: Yang Jingjing,  Liang Zhen,  Lu Ping,  Zhang Zhen,  Zhang Junjie DOI: 10.3760/cma.j.cn115989-20200807-00566 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 609-616. Abstract Objective To prepare vorinostat encapsulated hydroxypropyl-β-cyclodextrin (SAHA-CD) eye drops and investigate its inhibitory effect on corneal neovascularization (CNV) induced by alkali burns in mouse. Methods The SAHA-CD eye drops at concentrations […]

Differential expression analysis of circular RNA in human retinal vascular endothelial cells induced by high glucose

Authors: Jia Yangxue,  Wang Zhiling,  Wei Yingying,  Zhu Kai,  Gu Yonghao DOI: 10.3760/cma.j.cn115989-20200602-00390 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 617-622. Abstract Objective To investigate the differential expression profile of circular RNA (circRNA) in high glucose-cultured human retinal vascular endothelial cells (HRVECs). Methods HRVECs were divided into high glucose group, normal control group […]

Protective effect of myricitrin on retinal microvascular endothelial cells induced by high glucose and its regulation mechanism

Authors: Liu Qian,  Liu Changgeng,  Li Haijun,  Dong Yangzeng,  Zhang Ying DOI: 10.3760/cma.j.cn115989-20210809-00451 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 623-631. Abstract Objective To explore the effect of myricitrin on the injury of human retinal microvascular endothelial cells (HRMECs) induced by high glucose and its regulation mechanism. Methods HRMECs were divided into normal […]

Effect and safety of aflibercept in the treatment of polypoidal choroidal vasculopathy with ranibizumab-resistant serous pigment epithelial detachment

Authors: Zhou Pengyi,  Yang Lin,  Xu Youmei,  Pan Meng,  Guo Ju,  Du Liping,  Jin Xuemin DOI: 10.3760/cma.j.cn115989-20211206-00671 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 632-638. Abstract Objective To evaluate the effectiveness and safety of intravitreal injection of different doses of aflibercept for polypoidal choroidal vasculopathy (PCV) with serous pigment epithelial detachment (PED) resistant […]

Diagnostic value of OCTA and FFA in central serous chorioretinopathy complicated with choroidal neovascularization: a meta-analysis

Authors: Chen Jun,  Jia Chen,  Yu Xuhui DOI: 10.3760/cma.j.cn115989-20200714-00494 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 639-644. Abstract Objective To systematically evaluate the diagnostic value of optical coherence tomography angiography (OCTA) and fluorescein fundus angiography (FFA) for choroidal neovascularization (CNV) in central serous chorioretinopathy (CSC). Methods PubMed, Cochrane Library, Web of Science, Embase, […]

Efficacy and safety of compound anisodine injection for anterior ischemic optic neuropathy: a meta-analysis

Authors: Liao Liang,  Wang Yan,  Wei Qiping DOI: 10.3760/cma.j.cn115989-20211026-00586 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 645-650. Abstract Objective To evaluate the efficacy and safety of compound anisodine (CA) injection for anterior ischemic optic neuropathy (AION). Methods Studies, which were randomized controlled trials (RCT) of CA with routine treatment for AION from PubMed, […]

Efficacy of minimally invasive vitreous surgery combined with or without anti-VEGF drug injection in PCV complicated with vitreous hemorrhage

Authors: Xu Tengyu,  Li Suyan,  Zhang Zhengpei,  Liu Haiyang,  Ji Sujuan,  Liu Yalu,  Xu Qing DOI: 10.3760/cma.j.cn115989-20210303-00142 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 651-657. Abstract Objective To compare the clinical effects of minimally invasive vitreous surgery with and without anti-vascular endothelial growth factor (VEGF) drugs for polypoid choroidal vascular disease (PCV) complicated […]

Comparison of the efficacy of conbercept and intravitreal dexamethasone implant Ozurdex in the treatment of diabetic macular edema

Auhtors: Gao Rongyu,  Liu Jiandong,  Zhu Fangxing,  Yang Juanjuan,  Xu Enpei,  Xu Xinyan DOI: 10.3760/cma.j.cn115989-20200225-00108 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 658-663. Abstract Objective To compare the efficacy and safety of intravitreal injection of anti-vascular endothelial growth factor drug conbercept and intravitreal dexamethasone implant Ozurdex in the treatment of diabetic macular edema […]