Tag: Metabolic memory

Inhibitory effect of miR-27b-3p and Nrf2 regulation on metabolic memory formation in human RPE cells

Authors: Lai Qiaoling,  Xie Ting,  Huang Yan DOI: 10.3760/cma.j.cn115989-20201208-00831 Published 2023-10-10 Cite as Chin J Exp Ophthalmol, 2023, 41(10): 970-979. Abstract                              【Download PDF】 【Read Full Text】 Objective To investigate the effect of microRNA-27b-3p (miR-27b-3p)/nuclear factor-E2-related factor 2 (Nrf2) on metabolic memory impairment […]

The alterations of PGC-1α expression and epigenetic modifications in the retina of streptozotocin-induced diabetic rats

Authors: Geng Shuang,  Chen Youxin,  Yao Xiang,  Xu Haiyan,  Zhang Gumuyang,  Xia Song,  Liu Ziyang DOI: 10.3760/cma.j.issn.2095-0160.2018.06.003 Published 2018-06-10 Cite as Chin J Exp Ophthalmol, 2018,36(6): 410-416. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the role of epigenetic regulations of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) in the development […]