Authors: Jing Qinghe, Kong Hongyu, Zhao Chen DOI: 10.3760/cma.j.cn115989-20210322-00196 Published 2024-01-10 Cite as Chin J Exp Ophthalmol, 2024, 42(1): 80-85. Abstract [Download PDF] [Read Full Text] Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly worldwide and is […]
Tag: Retinal pigment epithelium
Research progress of in vitro experimental models in retinal light irradiation
Authors: Xu Yihua, Zhu Hong DOI: 10.3760/cma.j.cn115989-20200520-00364 Published 2023-12-10 Cite as Chin J Exp Ophthalmol, 2023, 41(12): 1243-1248. Abstract [Download PDF] [Read Full Text] With the popularity of electronic devices and the increasing environmental light pollution, more attention has been paid to the […]
Inhibitory effect of miR-27b-3p and Nrf2 regulation on metabolic memory formation in human RPE cells
Authors: Lai Qiaoling, Xie Ting, Huang Yan DOI: 10.3760/cma.j.cn115989-20201208-00831 Published 2023-10-10 Cite as Chin J Exp Ophthalmol, 2023, 41(10): 970-979. Abstract 【Download PDF】 【Read Full Text】 Objective To investigate the effect of microRNA-27b-3p (miR-27b-3p)/nuclear factor-E2-related factor 2 (Nrf2) on metabolic memory impairment […]
Inhibitory effects of N-acetylcysteine and salubrinal on apoptosis of retinal pigment epithelial cells induced by all-trans-retinoic acid
Authors: Wu Juan, Cui Dongmei, Zeng Junwen DOI: 10.3760/cma.j.cn115989-20200414-00262 Published 2023-01-10 Cite as Chin J Exp Ophthalmol, 2023, 41(1): 16-21. Abstract [Download PDF] [Read Full Text] Objective To observe the effect of the antioxidant N-acetylcysteine (NAC) and selective endoplasmic […]
New insights into the integrity of intercellular junctions between retinal pigment epithelial cells
Authors: Wei Jiayi, Wang Fang DOI: 10.3760/cma.j.cn115989-20201212-00839 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 670-674. Abstract [View PDF] [Read Full Text] Retinal pigment epithelium (RPE) is composed of a layer of highly specialized hexagonal pigment epithelial cells.The apical surface of […]
Effect of ROS/NLRP3/Caspase-1 signaling pathway on the apoptosis of retinal pigment epithelial cells induced by high glucose
Authors: Li Hongsong, Li Rong, Wang Lijun, Liao Dingying, Wang Jianming DOI: 10.3760/cma.j.cn115989-20210420-00267-1 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 6-12. Abstract [View PDF] [Read Full Text] Objective To investigate the effect of the nucleotide-binding domain, leucine-rich-containing family, pyrin […]