Category: 2016, No. 04

Phase portrait analysis of eye movement waveforms in congenital nystagmus eyes

Authors:Du Juan,  Shi Xuefeng,  Zhang Wei,  Wu Zhiqiang,  Zhao Kanxing DOI: 10.3760/cma.j.issn.2095-0160.2016.04.009 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 330-334. Abstract Background The characteristics of eye movement waveforms in congenital nystagmus eyes is so complicated that the time-series waveform can hardly demonstrate the oscillational kinetic property of the eye movement of nystagmus, which is […]

Dynamic expressions of matrix metalloproteinase-2 and its inhibitor in conjunctival filtering blebs of rats following glaucoma filtering surgery

Authors:Liu Mengying,  Wang Ling,  Wang Dabo,  Yao Ruyong DOI: 10.3760/cma.j.issn.2095-0160.2016.04.008 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 324-329. Abstract Background The scarring of conjunctival filtering blebs after glaucomatous surgery is a leading cause of operation failure.Exploring the balance between matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in conjunctival filtering bleb is […]

Promoting effect of Toll like receptor 4 on oxygen-induced retinal neovascularization and its mechanism

Authors:Xu Wenqin,  Yin Jie,  Wang Yusheng DOI: 10.3760/cma.j.issn.2095-0160.2016.04.007 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 317-323. Abstract Background Studies showed that Toll like receptors (TLRs) play an important role in the development of retinal angiogenesis.However, the effect and mechanism of TLR4 affecting angiogenesis in oxygen induced retinopathy (OIR) had not been clarified yet. Objective […]

Effect of large conductance Ca2+-activated K+ channel current and cytosolic calcium concentrations in retinal artery smooth muscle cells on diabetic retinal artery tension

Authors:Shao Jun,  Yao Yong,  Sun Wei,  Wang Ruxing DOI: 10.3760/cma.j.issn.2095-0160.2016.04.006 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 312-316. Abstract Background Diabetic retinopathy (DR) is a common microvascular complications of the retina, retinal vascular smooth muscle cells of large conductance calcium-activated potassium channels (BK) is a major factor in regulating vasomotor and hemodynamic.Currently, functional changes […]

A comparative study of two common optic nerve crush models in rats

Authors:An Jing,  Yin Hao,  Zhang Zuoming DOI: 10.3760/cma.j.issn.2095-0160.2016.04.004 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 305-311. Abstract Background Optic nerve crush (ONC) model is an available tool in the basic research on the mechanism and treatment of optic nerve injury.The opening optic nerves sheath crushing and via bulbar conjunctiva lateral canthus optic nerves crushing […]

Response properties of neurons and synaptic plasticity during pre-critical period of visual development in mouse visual cortex

Authors:Shi Xuefeng,  Zhao Kanxing DOI: 10.3760/cma.j.issn.2095-0160.2016.04.003 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 298-304. Abstract Background The visual development is completed during the critical period in human and mammals.However, the critical period is not the initial of receiving visual experience.It is known that before the onset of critical period in mammals, such as mouse, […]

Effects of groupⅠmetabotropic glutamate receptor on the synaptic transmission efficiency of the neurons in primary visual cortex of monocular form deprivated rats

Authors:Zhang Rui,  Liu Xiangling,  Lu Chengbiao,  Liu Zhihua,  Lin Jingjing,  Chen Yong,  Wang Yuanyue DOI: 10.3760/cma.j.issn.2095-0160.2016.04.002 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 293-297. Abstract Background The formation of amblyopia is closely associated with glutamate receptors of visual cortex, and researches determined that the expression of metabolic glutamate receptor 1 (mGluR1) in the visual […]

Towards objective assessment of the inner retinal functions

Authors:Bo Lei DOI: 10.3760/cma.j.issn.2095-0160.2016.04.001 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 289-292. Abstract Retinal anatomic structure and physiology function are very complex.Electroretinogram (ERG) is currently the only objective assessment for retinal function.There are groups of devastating diseases characterized by affecting the inner retinal functions.However, compared with its advantages in evaluating the outer retina function, […]