Authors: Liang Xiaofang, Sui Ruifang, Dong Fangtian DOI: 10.3760/cma.j.issn.2095-0160.2015.08.020 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 764-767. Abstract [Download PDF] [Read Full Text] Achromatopsia is a kind of autosomal recessive cone disorder. It occurs with nystagmus, photophobia, inability of color […]
Tag: Disease models
Inhibition of bone marrow mesenchymal stem cell autologous transplantation on inflammation following rabbit corneal alkali burn
Authors: Wu Li’an, Wang Congyi, Yang Wen, Yang Xinguang, Zhang Lin, Wang Jiahui DOI: 10.3760/cma.j.issn.2095-0160.2015.09.007 Published 2015-09-10 Cite as Chin J Exp Ophthalmol, 2015,33(9): 798-804. Abstract [Download PDF] [Read Full Text] Background Ocular alkali burns leads to corneal ulcer and angiogenesis and […]
Inhibitory effects of mesenchymal stem cells on antigen-specific T cells and antigen presenting cells in experimental autoimmune uveitis
Authors: Bai Lingling, Zhang Lingjun, Zheng Hui, Wang Meiyan, Dong Lijie, Li Xiaorong, Zhang Xiaomin DOI: 10.3760/cma.j.issn.2095-0160.2015.10.002 Published 2015-10-10 Cite as Chin J Exp Ophthalmol, 2015,33(10): 870-875. Abstract [Download PDF] [Read Full Text] Background Our previous studies found that mesenchymal stem cells (MSCs) […]
Changes of Th17 positive splenocytes and retinal interleukin-17 expression in rats with traumatic optic neuropathy
Authors: Zheng Huabin, Yan Hua DOI: 10.3760/cma.j.issn.2095-0160.2015.10.003 Published 2015-10-10 Cite as Chin J Exp Ophthalmol, 2015,33(10): 876-880. Abstract [Download PDF] [Read Full Text] Background Studies showed that traumatic optic neuropathy (TON) can activate and induce immuno-inflammatory response, while T helper cell 17 (Th17), […]
Protective role of anti-TLR2 monoclonal antibody to corneal graft survival after allograft corneal transplantation in rats
Authors: Bai Lang, Zheng Yanhua, Liang Weiyi DOI: 10.3760/cma.j.issn.2095-0160.2015.10.005 Published 2015-10-10 Cite as Chin J Exp Ophthalmol, 2015,33(10): 887-891. Abstract [Download PDF] [Read Full Text] Background The effects of Toll-like receptor 2 (TLR2) in grafting-related immune diseases have attracted more and more […]
Construction of murine model of TAO by immunification with recombinant extracellular domain of human thyrotropin receptor in cationic liposomes
Authors: Yang Yuli, Luo Qingli, Lyu Hongbin DOI: 10.3760/cma.j.issn.2095-0160.2015.11.004 Published 2015-11-10 Cite as Chin J Exp Ophthalmol, 2015,33(11): 974-980. Abstract [Download PDF] [Read Full Text] Background Thyroid-associated ophthalmopathy (TAO) is a kind of clinically common and incurable ocular disease, and its incidence […]
Modification and evaluation of ameliorative oxygen-induced retinopathy mouse model
Authors: Liu Aihua, Sun Jing, Zhang Hong DOI: 10.3760/cma.j.issn.2095-0160.2015.12.012 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1108-1112. Abstract [Download PDF] [Read Full Text] Background Retinal neovascularization is associated with various disorders.Studying the pathogenesis of retinal neovascularization is of important significance.Oxygen-induced retinopathy(OIR) […]
Application of CRISPR/Cas9 gene editing technology in the construction of animal models of ophthalmic diseases
Authors: Ma Xiaochen, Liu Hongling DOI: 10.3760/cma.j.cn115989-20190930-00425 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 972-975. Abstract [View PDF] [Read Full Text] The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated endonuclease 9 (Cas9) technology is a gene editing technology that uses […]
Advances in rodent models of retinal neovascularization
Authors: Xu Qianhui, Chen Jun, Shao Yi DOI: 10.3760/cma.j.cn115989-20200211-00064 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 996-998. Abstract [View PDF] [Read Full Text] Retinal neovascularization (RNV) originating from retinal blood vessels is one of the main pathological features of many ocular […]
Effect of integrin ανβ3 on conjunctival scar formation after glaucoma filtration surgery in rats
Authors: Zhu Xiaoyan, Xie Lin, Tan Wei DOI: 10.3760/cma.j.cn115989-20190917-00398 Published 2021-12-10 Cite asChin J Exp Ophthalmol, 2021, 39(12): 1046-1052. Abstract [View PDF] [Read Full Text] Objective To investigate the expression of integrin ανβ3 in conjunctival scar after glaucoma filtration surgery and to explore its role […]