Tag: Optic nerve injury

Single-cell sequencing technology in exploring the role of microglia in glaucomatous optic nerve injury

Authors: Qiu Leyi, Yuan Huiping DOI: 10.3760/cma.j.cn115989-20241211-00346 Published: 2026 -03 -10 Citation Qiu Leyi, Yuan Huiping. Single-cell sequencing technology in exploring the role of microglia in glaucomatous optic nerve injury[J]. Chin J Exp Ophthalmol, 2026, 44(3):286-290. DOI: 10.3760/cma.j.cn115989-20241211-00346. ABSTRACT                   [Download PDF]  [Read Full Text] Glaucoma is characterized by the progressive damage […]

Changes in energy metabolism associated with optic nerve injury in glaucoma

Authors: Yuan Qianmei, Yuan Huiping DOI: 10.3760/cma.j.cn115989-20231120-00178 Published:  2026 -03 -10 Citation Yuan Qianmei, Yuan Huiping. Changes in energy metabolism associated with optic nerve injury in glaucoma[J]. Chin J Exp Ophthalmol, 2026, 44(3):307-310. DOI: 10.3760/cma.j.cn115989-20231120-00178. ABSTRACT                   [Download PDF]  [Read Full Text] The slow progressive injury of retinal ganglion cells is […]

Research progress on protective strategies for optic nerve injury

Authors: Yu Jinhai,  Liao Hongfei,  Wang Yaohua DOI: 10.3760/cma.j.cn115989-20191226-00559 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1090-1094. Abstract                              [View PDF] [Read Full Text] Traumatic optic neuropathy and glaucoma can cause optic nerve degenerative changes leading to a significant decline […]

Repair effect of platelet-rich plasma on traumatic optic nerve injury in rabbits and its mechanism

Authors: Li Linling,  Xing Yiqiao DOI: 10.3760/cma.j.cn115989-20200701-00468 Published 2021-03-10 Cite as Chin J Exp Ophthalmol, 2021, 39(3): 198-206. Abstract                               [View PDF] [Read Full Text] Objective To study the therapeutic effect and mechanism of autologous platelet-rich plasma (PRP) on rabbit traumatic optic neuropathies (TON) and retina. […]

A comparative study of two common optic nerve crush models in rats

Authors: An Jing,  Yin Hao,  Zhang Zuoming DOI: 10.3760/cma.j.issn.2095-0160.2016.04.004 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 305-311. Abstract                              [Download PDF] [Read Full Text] Background Optic nerve crush (ONC) model is an available tool in the basic research on the mechanism and treatment of optic […]

Research progress of the related cytokines of Th1 and Th2 on glaucoma

Authors: Shang Huan,  Zhang Chun DOI: 10.3760/cma.j.issn.2095-0160.2017.11.020 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 1052-1056. Abstract                              [Download PDF] [Read Full Text] Glaucoma is a leading cause of irreversible blindness, which includes visual field defects and chronic degenerative diseases of the optic […]

Activation of retinal and optic nerve microglia following optic nerve crush in rats

Authors: Nie Zuqing,  Zhang Qiong,  Cao Xia DOI: 10.3760/cma.j.issn.2095-0160.2017.12.002 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1060-1066. Abstract                               [Download PDF] [Read Full Text] Background Traumatic optic neuropathy (TON) is an acute injury of the optic nerve secondary to trauma.As an important immune cell, microglia is involved […]