Authors: Wang Manqiao, Li Xiaorong DOI: 10.3760/cma.j.cn115989-20201012-00688 Published 2024-01-10 Cite as Chin J Exp Ophthalmol, 2024, 42(1): 93-96. Abstract [Download PDF] [Read Full Text] Secretogranin Ⅲ (SCG3) is a kind of secretory granule widely distributed in tissues and cells with endocrine functions […]
Tag: Angiogenesis
Modification and evaluation of ameliorative oxygen-induced retinopathy mouse model
Authors: Liu Aihua, Sun Jing, Zhang Hong DOI: 10.3760/cma.j.issn.2095-0160.2015.12.012 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1108-1112. Abstract [Download PDF] [Read Full Text] Background Retinal neovascularization is associated with various disorders.Studying the pathogenesis of retinal neovascularization is of important significance.Oxygen-induced retinopathy(OIR) […]
Inhibitory effect of rosmarinic acid on high glucose-induced angiogenesis of human retinal microvascular endothelial cells and the activation of NLRP3 inflammasome pathway
Authors: Fan Jiangli, Guan Yanling, Li Rong, Yao Yang DOI: 10.3760/cma.j.cn115989-20191203-00520 Published 2021-11-10 Cite asChin J Exp Ophthalmol, 2021, 39(11): 940-948. Abstract [View PDF] [Read Full Text] Objective To investigate the inhibitory effects of rosmarinic acid (RA) on high glucose-induced angiogenesis of human retinal microvascular […]
Promoting effect of Toll like receptor 4 on oxygen-induced retinal neovascularization and its mechanism
Authors: Xu Wenqin, Yin Jie, Wang Yusheng DOI: 10.3760/cma.j.issn.2095-0160.2016.04.007 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 317-323. Abstract [Download PDF] [Read Full Text] Background Studies showed that Toll like receptors (TLRs) play an important role in the development of retinal angiogenesis.However, the effect and […]
Research progress on genetics of familial exudative vitreoretinopathy
Authors: Tang Miao, Li Zijing, Ding Xiaoyan DOI: 10.3760/cma.j.issn.2095-0160.2016.06.017 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 558-561. Abstract [Download PDF] [Read Full Text] Familial exudative vitreoretinopathy (FEVR) is an inherited retinal disorder characterized by abnormal vascularization of the peripheral retina with a variety of phenotypes.Genetic […]
Relationship of human microvascular endothelial cell activation and adenosine level under the hypoxia
Authors: Ai Liqianyu, Huang Chanjuan, Chen Chen, Lin Sen, Ye Jian DOI: 10.3760/cma.j.issn.2095-0160.2017.01.006 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 26-31. Abstract [Download PDF] [Read Full Text] Background Retinal hypoxia is one of primary causes of retinal neovascularization, and its mechanism is research hot topic.Studies showed that hypoxia […]
The promoting effects of insulin-like growth factor 1 on the biological behaviour of human retinal vascular endothelial cells
Authors: Wang Mengjiao, Liu Gaoqin, Xu Jing, Li Dan, Lu Peirong DOI: 10.3760/cma.j.issn.2095-0160.2017.05.007 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 417-422. Abstract [Download PDF] [Read Full Text] Background The suppression of retinal angiogenesis is one of primary treatment targets for retinal vascular diseases, so seeking the intervention targets […]
Effect of apelin/APJ in retinal vascular diseases
Authors: Chen Li, Bai Yujing, Jiang Yanrong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.018 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 936-939. Abstract [Download PDF] [Read Full Text] The G protein-coupled receptor was deorphanized with cloning of the APJ-endogenous ligand apelin, which is an important active peptides.Apelin/APJ system is widely distributed […]
Role of autophagy in angiogenesis of retinal vascular endothelial cells under hypoxia condition
Authors: Li Rong, Du Junhui, Yao Yang, Yu Zhaoxiang, Fan Zhuo, Chang Weiping DOI: 10.3760/cma.j.issn.2095-0160.2018.03.006 Published 2018-03-10 Cite as Chin J Exp Ophthalmol, 2018,36(3): 187-193. Abstract [Download PDF] [Read Full Text] Objective To study the role of autophagy in proliferation, migration and tube formation of retinal vascular endothelial cells (RVECs) under […]
Comparision of the pharmacodynamics between different batches of recombinant decoy receptor innovative drug RC28-E in retinal vascular endothelial cells
Authors: Zheng Jialin, Yang Qianhui, Sun Jing, Zhang Hong, Jiang Jing, Huang Min, Li Shenjun, Fang Jianmin, Li Xiaorong, Zhang Yan DOI: 10.3760/cma.j.issn.2095-0160.2018.12.003 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 908-913. Abstract [Download PDF] [Read Full Text] Objective To compare the protective effects of pharmacological batch RC28-E1 and pilot batch RC28-E2 on retinal […]