Category: 2016

Identification of genetic mutation in a Chinese pedigree with congenital cataract by whole-exome sequencing

Authors:Bu Juan,  Liu Jing,  Pang Honglei,  Liu Feng,  Wang Lejin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.006 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 896-899. Abstract                            [Download PDF] [Read Full Text]  Background Genetic mutation remains to be the most common cause of congenital cataract.Whole exon sequencing technology is an ideal […]

The efficiency and safety assessment of Entranster™ nanoparticle carrier for CD25 siRNA transfection in rat cornea

Authors:Qin Qin,  Shi Yunjie,  Zhao Min DOI: 10.3760/cma.j.issn.2095-0160.2016.10.005 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 888-895. Abstract                              [Download PDF] [Read Full Text] Background Gene transfection is an effective therapeutic avenue to target many kinds of eye diseases.Non-viral vectors with high transfection efficiency, long-term expression, […]

Identification of pathgenic bacteria in aqueous and vitreous of endophthalmitis by 16S rDNA sequencing technique

Authors: Yang Baoxia,  Li Hong,  Kong Fanfang,  Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2016.10.004 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 883-887. Abstract                              [Download PDF] [Read Full Text] Background Endophthalmitis is a serious complication of intraocular surgery.Conventional identification methods for bacteria are becterial culture and smear method, […]

Detection and analysis of differential gene expression between benign lymphoepithelial lesion of lacrimal gland and orbital cavernous hemangioma

Authors:Li Jing,  Ge Xin,  Ma Jianmin,  Wang Xiaona,  Liu Xiao DOI: 10.3760/cma.j.issn.2095-0160.2016.10.003 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 878-882. Abstract                            [Download PDF] [Read Full Text] Background Benign lymphoepithelial lesion of lacrimal gland is not a common orbital disease in clinic, which mainly presented as […]

Changes of collapsin response mediator protein-2 and its phosphorylated protein levels following optic nerve injury

Authors:Chen Xiaofan,  Yuan Rongdi,  Ye Jian,  Chen Chunlin DOI: 10.3760/cma.j.issn.2095-0160.2016.10.002 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 874-877. Abstract                            [Download PDF] [Read Full Text] Background Collapsin response mediator protein-2 (CRMP-2) can promote the growth of axons, but CRMP-2 occurs hyperphosphorylation under the induction of cyclin-dependent […]

A 5-year prospective study of type 2 diabetes patients in Shanghai Xinjing Community 3.The regression and promoting factors of diabetic retinopathy and diabetic macular edema in Chinese type 2 diabetes patients

Authors:Jin Peiyao,  Peng Jinjuan,  Zou Haidong,  Xu Xun,  Zhang Xi,  Wang Weiwei,  Fu Jiong,  Bai Xuelin DOI: 10.3760/cma.j.issn.2095-0160.2016.11.014 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 1025-1030. Abstract                              [Download PDF] [Read Full Text] Background Long-term study on type 2 diabetes discovered that some patients with diabetic retinopathy (DR) or diabetic macular edema (DME) appear […]

The era of minimally invasive glaucoma surgery

Authors:Zhou Jichao,  Zhang Chun DOI: 10.3760/cma.j.issn.2095-0160.2016.11.020 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 1052-1056. Abstract                               [Download PDF] [Read Full Text] The chance of glaumatic optic nerve injury increases with the intraocular pressure.Reducing the intraocular pressure has an important significance for slowing the process of glaucoma.Surgery is one […]

Current research of hyaluronic acid and thyroid-associated ophthalmopathy

Authors:Chen Xiaoling,  He Weimin DOI: 10.3760/cma.j.issn.2095-0160.2016.11.018 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 1047-1050. Abstract                               [Download PDF] [Read Full Text] Thyroid-associated ophthalmopathy (TAO) is a common orbital disease in the adults, and glycosaminoglycan deposits in the periorbital connective tissue is one of important pathological features.Hyaluronic acid is […]

A review of the association between nuclear receptors and ocular diseases

Authors:Liu Ke,  Qin Bo,  Zou Chang DOI: 10.3760/cma.j.issn.2095-0160.2016.11.017 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 1042-1046. Abstract                              [Download PDF] [Read Full Text] Nuclear receptor is one of abundant transcription factors in human body.Interacted with corresponding ligands, coactivators and corepressors, nuclear receptor can regulate the expression of genes and […]