Category: 2018, No. 08

The research progress of macular telangiectasia type 2

Authors: Liu Chengxi,  Ding Xiaoyan DOI: 10.3760/cma.j.issn.2095-0160.2018.08.016 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 653-656. Abstract Macular telangiectasia type 2 (MacTel type 2) is a kind of disease that characterized by the dilation of capillary in temporal macula lutea and the degeneration of neurosensory retina.It usually affects both eyes in patient aged 50 to 60.The […]

Recent advances of bevacizumab as an adjunct to trabeculectomy

Authors: Chen Juan,  Yu Wenzhen DOI: 10.3760/cma.j.issn.2095-0160.2018.08.015 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 649-652. Abstract Glaucoma is a group of diseases characterized by progressive optic nerve damage and characteristic visual field defect.Increased intraocular pressure is the main risk factor for glaucoma progression.Trabeculectomy combined with adjunctive antimetabolites has been commonly used in glaucoma treatment currently.Several […]

The relationship between primary open angle glaucoma and blood flow abnormalities

Authors: Tian Jiaxin,  Wang Ningli DOI: 10.3760/cma.j.issn.2095-0160.2018.08.014 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 643-648. Abstract As one of the common types of glaucoma, primary open angle glaucoma (POAG) occurs insidiously with conditions, such as patients have normal intraocular pressure while accompanying with glaucomatous optic nerve damage, or the intraocular pressure is reduced to normal […]

Research progress of pathological relevant cytokines of neovascular eye diseases

Authors: Han Mengyu,  Wang Zhijun,  Jin Ming DOI: 10.3760/cma.j.issn.2095-0160.2018.08.013 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 636-642. Abstract Neovascular eye diseases, with highly complicated and refractory, are one group of the most difficult problems for domestic and overseas clinical oculists in recent years.Angiogenesis is a complex process participating with multiple factors and various ways, and its […]

Relationship between the changes of high-sensitivity C-reactive protein and retinal vessel diameter in the middle-aged and elderly: the Kailuan Study

Authors: Liu Xinxin,  Lu Aidong,  Wang Yaxing,  Wei Wenbin,  Chen Shuohua,  Wu Shouling DOI: 10.3760/cma.j.issn.2095-0160.2018.08.012 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 629-635. Abstract Objective To investigate the relationship between high-sensitivity C-reactive protein (hsCRP) and retinal vascular diameter. Methods This study was a cross-sectional study, the population was from the Kailuan study (clinical trial research registration NO.: ChiCTR-TNC-1100 1489) […]

The application of ultra-wide field fluorescein angiography in the evaluation of peripheral vascular changes following retinal vein occlusion

Authors:  Wang Linni,  Yu Rongguo,  Yang Jin,  Hu Liying,  Gong Xue,  Chen Lu,  Li Zhiqing,  Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2018.08.011 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 625-628. Abstract Objective To investigate the peripheral vascular findings in eyes with branch retinal vein occlusion (BRVO) and hemi-retinal vein occlusion (HRVO) using ultra-wide field fluorescein angiography (UWFFA), and analyze the influence of relative systemic […]

The efficacy of intravitreal injection of conbercept on different types of macular edema induced by branch retinal vein occlusion

Authors:  Xu Na,  Gao Rongyu,  Xu Xinyan,  Zhang Jie,  Sun Xianyong DOI: 10.3760/cma.j.issn.2095-0160.2018.08.010 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 619-624. Abstract Objective To investigate the clinical efficacy of intravitreal injection of conbercept on different types of macular edema (ME) induced by branch retinal vein occlusion (BRVO). Methods A prospective case-control study was designed.Fifty-six eyes of 56 patients […]

Intravitreal ranibizumab injection combined trabeculectomy versus Ahmed glaucoma valve implantation in the treatment of neovascular glaucoma

Authors:  Gao Lin,  Liu Wei DOI: 10.3760/cma.j.issn.2095-0160.2018.08.009 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 613-618. Abstract Objective To evaluate and compare the efficacy and safety of intravitreal ranibizumab injection combined trabeculectomy and intravitreal ranibizumab injection combined Ahmed glaucoma valve implantation in the treatment of neovascular glaucoma (NVG). Methods A retrospective case-control study was designed.The clinical […]

Effect of Eylea on recombinant AAV2-VEGF-induced choroidal neovascularization

Authors:  Jiang Laisheng,  Liao Qin,  Cai Keyang,  Sun Huiye,  Sun Yunxia DOI: 10.3760/cma.j.issn.2095-0160.2018.08.008 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 608-612. Abstract Objective To evaluate the effect of Eylea (aflibercept) on recombinant adeno-associated virus 2(AAV2)-vascular endothelial growth factor (VEGF)-induced choroidal neovascularization (CNV). Methods Two normal cynomolgus monkeys were used in this study.Recombinant AAV2-VEGF was delivered by subretinal injection […]

The suppression mechanisms of quercetin in retinal and choroidal neovascularization through integrin signal pathway

Authors:  Yue Yankun,  Wang Haiwei,  Deng Yu,  Tian Mo,  Wang Yinlin,  Zhang Enkui DOI: 10.3760/cma.j.issn.2095-0160.2018.08.007 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 602-607. Abstract Objective To investigate the mechanisms of quercetin in retinal angiogenesis via in vitro and in vivo studies. Methods Human umbilical vein endothelial cells (HUVECs) was used in in vitro study, and oxygen-induced retinopathy (OIR) and […]