Category: 2018, No. 09

Research progress of the relationship between Sirtuins and diabetic retinopathy

Authors: Gao Jian,  Xu Yajing,  Liu Lun DOI: 10.3760/cma.j.issn.2095-0160.2018.09.016 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 733-736. Abstract As one of the serious complications of diabetes melitus, diabetic retinopathy (DR) is one of the major causes of blindness.It is urgent to figure out the mechanism of DR and identify an effective therapeutic target to prevent it.Sirtuins […]

Research progress of dry eye secondary to chronic graft-versus-host disease

Authors: Zhang Haiqi,  Zhang Qi DOI: 10.3760/cma.j.issn.2095-0160.2018.09.015 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 728-732. Abstract Allogeneic hematopoietic stem cell transplantation (HSCT) is currently an important method for the treatment of malignant or severe conditions of hematogenous disorders.Chronic graft versus host disease (cGVHD) after allogeneic HSCT is the main factor affecting recipient lifespan and life-quality.Dry […]

Bacteriophage and its application in ocular diseases

Authors: Xu Shuo,  Zhang Hong DOI: 10.3760/cma.j.issn.2095-0160.2018.09.014 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 724-727. Abstract Phage (bacteriophage) is a kind of viruses which can infect bacteria, actinomyces and spirochetes.The phage can only reproduced by host bacteria instead of living independently.The process of phage reproduction is also the process of sterilization.Nowadays, the “post-antibiotic era” that […]

Research status of blepharokeratoconjunctivitis

Authors: Feng Xinyuan,  Deng Xinguo DOI: 10.3760/cma.j.issn.2095-0160.2018.09.013 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 719-723. Abstract Blepharokeratoconjunctivitis (BKC) is a chronic inflammatory disorder and can be defined as lid margin blepharitis accompanied by conjunctivitis and keratopathy.Typical clinical characteristics of BKC consisted of conjunctival hyperemia, papillary hyperplasia follicles, punctate keratitis, marginal keratitis, corneal punctuate epithelial erosion, […]

Research progress on the microbiota of ocular surface

Authors: An Na,  Liu Xianning DOI: 10.3760/cma.j.issn.2095-0160.2018.09.012 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 714-718. Abstract The microbiota of the ocular surface consists of diverse microbial communities and colonizes on the ocular mucous membrane including tear film.The symbiotic relationship maintains the stabilization of ocular biosystem and ensures its healthy status.The initiation of the Human Microbiome […]

Changes of chemokine receptors expression in the conjunctival epithelial cells and Th-17 cell number in tears of diabetic dry eye disease

Authors: Ren Ning,  Cui Hong,  Sun Lixia,  Li Yingjun DOI: 10.3760/cma.j.issn.2095-0160.2018.09.011 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 710-713. Abstract Objective To explore the expression of chemokine receptor 6 (CCR6) and T helper cell 17 (Th-17) in the epithelial cells and tears in diabetic patients with dry eye disease. Methods Prespective study was performed.Ninety-one type 2 diabetic […]

Conjunctival flora and their antibiotic susceptibility in patients undergoing penetrating intraocular surgeries

Authors: Ren Chunyang,  He Jingna,  Wang Lin,  Liu Shanshan,  Sun Jing,  Cao Yong,  Wang Hailin,  Li Ruoxi,  Zhang Shaodan DOI: 10.3760/cma.j.issn.2095-0160.2018.09.010 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 704-709. Abstract Objective To determine the spectrum of conjunctival flora and the antibiotic susceptibility profiles of patients scheduled for penetrating intraocular surgeries. Methods A prospective case control study was performed.A total of 192 patients […]

Long-term efficacy of intravitreal ranibizumab therapy for idiopathic choroidal neovascularization

Authors: Zhang Ming,  Di Rong,  Kang Qianyan,  Fan Xiaojuan DOI: 10.3760/cma.j.issn.2095-0160.2018.09.009 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 699-703. Abstract Objective To observe the long-term clinical efficacy of intravitreal ranibizumab (IVR) in patients with idiopathic choroidal neovascularization (ICNV), and to explore the indicators that affect curative effect. Methods A retrospective self-controlled study was performed.The clinical data of […]

The prognosis of ocular inflammation index after pterygium surgery based on Oculus Keratograph® 5M and Visual analogue scale

Authors:  Huang Haixiang,  Yuan Jin,  Li Saiqun,  Zhang Henan,  Yang Ruhui,  Deng Yuqing,  Wang Bowen,  Peng Lulu,  Zhong Jing DOI: 10.3760/cma.j.issn.2095-0160.2018.09.008 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 693-698. Abstract Objective To investigate the characteristics of ocular surface inflammation index after pterygium excision by using Oculus Keratograph® 5M and Visual analogue scale and evaluated the effectiveness of anti-inflammatory treatment. Methods A prospective […]

Research on the relationship between clinical features of patients with Demodex blepharitis and diagnosis

Authors: Zhang Yang,  Sun Xuguang DOI: 10.3760/cma.j.issn.2095-0160.2018.09.007 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 688-692. Abstract Objective To analyze the signs of Demodex infection on palpebral margin and to accurately evaluate the indications of the eyelash examination for Demodex, which can provide a reliable basis for the pathogenic diagnosis. Methods A prospective case observational study […]