Authors: Chen Jia, Yang Ying, Su Shu, Zhang Shenglai, Yang Xiaowei, Sang Aimin DOI: 10.3760/cma.j.cn115989-20240207-00042 Published: 2025 -10 -10 Citation Chen Jia, Yang Ying, Su Shu, et al. Promotive effect of hypoxia-induced ANGPTL4 expression on experimental choroidal neovascularization[J]. Chin J Exp Ophthalmol, 2025, 43(10):906-914. DOI: 10.3760/cma.j.cn115989-20240207-00042. ABSTRACT […]
Tag: Hypoxia
Targets and validation of Salvia miltiorrhiza in myopia through network pharmacology
Authors: Lu Xiaonan, Li Jie, An Guangqi, Liu Zhenhui, Liang Chunyu, Dai Shuzhen DOI: 10.3760/cma.j.cn115989-20231209-00205 Published 2024-04-10 Cite as Chin J Exp Ophthalmol, 2024, 42(4): 322-328. Abstract 【Download PDF】 【Read Full Text】 Objective To explore and validate the targets of Salvia miltiorrhiza in myopia using […]
Restrain of hypoxia on the expression of annexin A2 in mouse RGC-5 cells
Authors: Yan Lin, Yang Xia, Wang Longmei, Dong Xiaoguang, Xu Haifeng DOI: 10.3760/cma.j.issn.2095-0160.2015.12.006 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1077-1082. Abstract [Download PDF] [Read Full Text] Background Hypoxia is the main factor of retinal neovascularization and is closely associated with […]
Transcriptomics analysis of hypoxia-induced retinal pigment epithelium cell injury
Authors: Lu Cong, Shi Pingling, Yang Qixiang, Song Hao, Li Miao, Zhang Beibei, Song Zongming DOI: 10.3760/cma.j.cn115989-20201127-00799 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 505-514. Abstract [View PDF] [Read Full Text] Objective To analyze differentially expressed genes (DEGs) and the changes of signal […]
Inhibitory effects of NADPH oxidase 4 inhibitor on VEGF expression in hypoxia-induced human RPE cells
Authors: Li Jing, Yang Jing, Kang Qianyan DOI: 10.3760/cma.j.issn.2095-0160.2020.01.002 Published 2020-01-10 Cite as Chin J Exp Ophthalmol, 2020,38(01): 4-9. Abstract [View PDF] [Read Full Text] Objective To observe the inhibitory effects of nicotinamide adenine dinucleotide phosphate oxidase 4 (NOX4) on vascular endothelial […]
The inhibitory effects of baicalein on overexpression of proline hydroxylase 2 in hypoxia-induced retinal glial cells
Authors: Yang Ning, Lu Qiang, Yuan Mengke, Zhang Han, Cui Wei DOI: 10.3760/cma.j.issn.2095-0160.2017.11.007 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 990-996. Abstract [Download PDF] [Read Full Text] Background Proline hydroxylase 2 (PHD2) is a degrading enzyme of hypoxia-inducible factor-1α (HIF-1α) and can regulate the expression of vascular endothelial […]
The promoting effects of SNAI1 activating matrix metalloproteinase on choroidal neovascularization under hypoxia
Authors: Sun Jiaxing, Dou Guorui, Chang Tianfang, Li Manhong, Yang Ziyan, Yan Xianchun, Liu Yuan, Han Hua, Wang Yusheng DOI: 10.3760/cma.j.issn.2095-0160.2018.01.004 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 16-22. Abstract [Download PDF] [Read Full Text] Objective To investigate whether vascular endothelial cells in choroidal neovascularization whether hypoxia condition can up-regulate SNAI1 and […]
Role of autophagy in angiogenesis of retinal vascular endothelial cells under hypoxia condition
Authors: Li Rong, Du Junhui, Yao Yang, Yu Zhaoxiang, Fan Zhuo, Chang Weiping DOI: 10.3760/cma.j.issn.2095-0160.2018.03.006 Published 2018-03-10 Cite as Chin J Exp Ophthalmol, 2018,36(3): 187-193. Abstract [Download PDF] [Read Full Text] Objective To study the role of autophagy in proliferation, migration and tube formation of retinal vascular endothelial cells (RVECs) under […]
Research progress of the relationship between Sirtuins and diabetic retinopathy
Authors: Gao Jian, Xu Yajing, Liu Lun DOI: 10.3760/cma.j.issn.2095-0160.2018.09.016 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 733-736. Abstract [Download PDF] [Read Full Text] As one of the serious complications of diabetes melitus, diabetic retinopathy (DR) is one of the major causes of blindness.It is urgent to […]