Category: 2018, No. 12

The protective effect of paeoniflorin in retina ischemia animal model through regulation of NLRP3 inflammasomes

Authors:  Yang Peiyao,  Zhao Jun,  Zhang Juanmei,  Gao Yunxia,  Zhan Weijiao,  Wang Yun,  Wang Qiang,  Xue Youyu  DOI: 10.3760/cma.j.issn.2095-0160.2018.12.005 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 920-924. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the mechanisms of paeoniflorin in protection of retinal ischemia injury. Methods Fifty-four male specefic pathogen […]

The facilitation of corneal permeability of cyclosporine A loaded on chitosan-graft-cyclodextrin copolymers vector

Authors: Li Jingguo,  Zhou Tianyang,  Li Zhanrong,  Liang Zhen,  Xia Huiyun,  He Jijun,  Zhang Junjie DOI: 10.3760/cma.j.issn.2095-0160.2018.12.004 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 914-919. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the corneal permeability of cyclosprin A (CsA) loaded on polymeric vector after topical application. Methods The […]

Comparision of the pharmacodynamics between different batches of recombinant decoy receptor innovative drug RC28-E in retinal vascular endothelial cells

Authors: Zheng Jialin,  Yang Qianhui,  Sun Jing,  Zhang Hong,  Jiang Jing,  Huang Min,  Li Shenjun,  Fang Jianmin,  Li Xiaorong,  Zhang Yan DOI: 10.3760/cma.j.issn.2095-0160.2018.12.003 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 908-913. Abstract                               [Download PDF] [Read Full Text] Objective To compare the protective effects of pharmacological batch RC28-E1 and pilot batch RC28-E2 on retinal […]

Inhibitory effect of rapamycin on proliferation, migration and fibrosis of human pterygium fibroblasts in vitro

Authors: Wu Di,  Sun Xiaonan,  Du Lin,  Zhang Xiaoyu,  Liu Shanshan,  Sun Jing,  Xu Lin,  Zhang Shaodan DOI: 10.3760/cma.j.issn.2095-0160.2018.12.002 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 902-907. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the inhibitory effect of rapamycin, an mammalian target of rapamycin (mTOR) […]

Pay more attention to drug-induced ocular toxicity

Authors:  Zhang Junjie DOI: 10.3760/cma.j.issn.2095-0160.2018.12.001 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 897-901. Abstract                              [Download PDF] [Read Full Text] Medication safety is one of the primary considerations in drug therapy.With the increase of drug categories and the diversification of drug delivery routes, more and […]