Tag: Rapamycin

Advance in research on the relationship between mammalian target of rapamycin signaling pathway and ophthalmic diseases

Authors: Zhang Guiming,  Liu Hongling,  Fu Shaoying DOI: 10.3760/cma.j.issn.2095-0160.2015.11.018 Published 2015-11-10 Cite as Chin J Exp Ophthalmol, 2015,33(11): 1048-1051. Abstract                              [Download PDF] [Read Full Text] Mammalian target of rapamycin (mTOR) is a highly evolutionary conserved protein kinase and plays a critical role […]

The pilot study on rapamycin retarding the differentiation of RPE cells in vitro

Authors: Jiang Chao,  Zhao Chen,  Shi Houxia,  Ding Sijia DOI: 10.3760/cma.j.issn.2095-0160.2015.12.003 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1064-1068. Abstract                             [Download PDF] [Read Full Text] Background Retinal pigment epithelial (RPE) cell transplantation is a novel approach to the treatment of hereditary […]

Research progress of the protection of rapamycin for proliferative vitreoretinopathy

Authors: Liao Mengyu,  Yan Hua DOI: 10.3760/cma.j.cn115989-20200203-00048 Published 2023-01-10 Cite as Chin J Exp Ophthalmol, 2023, 41(1): 88-91. Abstract                              [Download PDF] [Read Full Text] Proliferative vitreoretinopathy (PVR) is a complication of ocular trauma, rhegmatogenous retinal detachment (RRD), and also a common cause […]

Protective effect of rapamycin on hypoxia-injuried retinal ganglion cells and its mechanism

Authors: Ren Jing,  Qin Bo,  Zou Chang,  He Jing,  Liu Shenwen DOI: 10.3760/cma.j.issn.2095-0160.2017.05.004 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 404-409. Abstract                               [Download PDF] [Read Full Text] Background Studies showed that rapamycin (Rapa) plays a protective effect on central nervous system by improving the aging of human brain […]

Inhibitory effect of rapamycin on proliferation, migration and fibrosis of human pterygium fibroblasts in vitro

Authors: Wu Di,  Sun Xiaonan,  Du Lin,  Zhang Xiaoyu,  Liu Shanshan,  Sun Jing,  Xu Lin,  Zhang Shaodan DOI: 10.3760/cma.j.issn.2095-0160.2018.12.002 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 902-907. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the inhibitory effect of rapamycin, an mammalian target of rapamycin (mTOR) […]