Category: 2018, No. 12

Advance in biomarkers of neuromyelitis optica

Authors: Chen Jun,  He Jianfeng,  Zhan Jialin  DOI: 10.3760/cma.j.issn.2095-0160.2018.12.016 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 973-976. Abstract Neuromyelitis optica (NMO) is an autoimmune, demyelinating disease of the central nervous system manifesting with optic neuritis and longitudinally extensive transverse myelitis.Aquaporin-4 (AQP4)-IgG is currently regarded as a specific biomarker of NMO.Nevertheless, AQP4-IgG seronegativity in 10%-25% of NMO […]

Individual difference of response to antiglaucoma drugs and its influencing factors

Authors: Zhang Shiqi,  Yuan Huiping DOI: 10.3760/cma.j.issn.2095-0160.2018.12.014 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 967-970. Abstract The application of antiglaucoma drugs is the main treatment for glaucoma, but there are differences in the response of patients to antiglaucoma drugs.Different races have different reactivities to prostaglandins; the same patient may has different reactivity to different prostaglandins; […]

Research progress of anti-VEGF for the therapy in wet age-related macular degeneration

Authors: Liu Shu,  Xu Xiaofang DOI: 10.3760/cma.j.issn.2095-0160.2018.12.013 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 962-966. Abstract Age-related macular degeneration (AMD) is the primary cause of the blindness among the population aged more than 50 years old.The prevalence of AMD increases with age growing.Wet AMD is the main cause of the visual impairment in over 90% […]

Dry eye animal models and dry eye drug development

Authors: Wang Weizhuo,  Chen Miao,  Lingyun Cheng DOI: 10.3760/cma.j.issn.2095-0160.2018.12.012 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 956-961. Abstract Dry eye is the most common eye illness which manifests as a chronic inflammation on ocular surface and imposes significant threat to vision.Though dry eye is high prevalent, specific medication to treat this refractory disorder is very limited.The […]

Research progress on mechanism of atropine in controlling myopia

Authors: Gong Boteng,  Wei Ruihua DOI: 10.3760/cma.j.issn.2095-0160.2018.12.011 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 951-955. Abstract The prevalence of myopia and high myopia has gradually increased, increased myopia is associated with an enhanced risk of pathological ocular complications and may lead to blinding disorders.The optometrists and parents initially pay more attention to juvenile myopia prevention […]

Intravitreal injection of conbercept during vitrectomy surgery to treat severe proliferative diabetic retinopathy

Authors: Li Cuiping,  Chen Song,  Wang Yun,  He Guanghui,  Zhang Wei,  Wang Ping,  Guo Jing DOI: 10.3760/cma.j.issn.2095-0160.2018.12.010 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 946-950. Abstract Objective To observe and analysis the clinical effects and postoperative complications of intravitreal injection of conbercept during vitrectomy surgery (VRS) in severe proliferative diabetic retinopathy (PDR) treatment. Methods This is a prospective non-randomized controlled […]

Ocular surface change of primary pterygium with OCULUS keratograph

Authors: Li Zhongting,  Leng Xuan,  Zhang Yanli,  Hu Tingxin,  Zhao Qi,  Yu Minbin DOI: 10.3760/cma.j.issn.2095-0160.2018.12.009 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 942-945. Abstract Objective To study the correlation between pterygium area and the clinical manifestation and signs of primary pterygium obtained from OCULUS Keratograph. Methods A prospective case observation study was performed.Thirty-nine (55 eyes) primary pterygium patients were […]

Effects of 0.3% sodium hyaluronate ophthalmic solution in the treatment of mild-to-moderate dry eye patients: a multi-center clinical study

Authors: Huang Caihong,  Liu Zuguo,  Li Wei,  Zhu Li,  Zhu Sisi,  Lin Xiang,  Ouyang Weijie,  Jiang Nan,  Xu Jianjiang,  Wu Dan,  Liang Lingyi,  Luo Xiaohui,  Wang Hua,  Chen Ting,  Chen Wei,  Zheng Qinxiang,  Sun Xuguang,  Deng Shijing DOI: 10.3760/cma.j.issn.2095-0160.2018.12.008 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 936-941. Abstract Objective To evaluate the efficacy of 0.3% sodium hyaluronate ophthalmic solution in mild-to-moderate dry eye patients. Methods A prospective, multicenter, and self-controlled clinical […]

The reaction pattern rules of mouse retinal ganglion cell under different wavelengths of light stimulation

Authors:  Lin Lixia,  Lou Bingsheng,  Yang Yao,  Zeng Jieting,  Lin Xiaofeng DOI: 10.3760/cma.j.issn.2095-0160.2018.12.007 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 931-935. Abstract Objective To explore the reaction pattern rules of mouse retinal ganglion cells potential under different wavelengths of light stimulation. Methods Thirty SPF grade 3-week-old C57BL/6 mice were used for ex vivo whole mount retina preparation.The cells […]

Inhibition of hepatocyte growth factor on proliferation and transdifferentiation of human Tenon capsule fibroblasts triggered by transforming growth factor-β1in vitro

Authors: Chen Jing,  Wang Yong,  Li Donghao DOI: 10.3760/cma.j.issn.2095-0160.2018.12.006 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 925-930. Abstract Objective To investigate the effects of hepatocyte growth factor (HGF) on proliferation and transdifferentiation of human Tenon capsule fibroblasts induced by transforming growth factor -β1 (TGF-β1) in vitro. Methods Human Tenon capsule fibroblasts were cultured and divided into […]