Category: 2018

Mutation analysis of the autosomal dominant Weill-Marchesani syndrome and genotype-phenotype review

Authors: Li Jie,  Xing Yasi,  Li Zhanrong,  Qin Fangyuan,  Dai Shuzhen DOI: 10.3760/cma.j.issn.2095-0160.2018.07.006 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 514-518. Abstract                              [Download PDF] [Read Full Text] Objective To screen the disease-causing genes in an autosomal dominant(AD)Weill-Marchesani syndrome (WMS) family from Henan province in […]

Effects of long noncoding RNA-MIAT on lens epithelial to mesenchymal transition induced by transforming growth factor-β2

Authors: Yue Xiujuan,  Su Sheng,  Wang Liyuan,  Lyu Jia,  Wang Lin,  Liu Ping DOI: 10.3760/cma.j.issn.2095-0160.2018.07.005 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 508-513. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the roles of long noncoding RNA-myocardial infarction-associated transcript (MIAT) on lens epithelial cells (LECs) fibrosis induced by […]

Expression dynamics of lens development-associated transcription factors in human embryonic stem cell-induced lentoid body

Authors: Han Chenlu,  Wang Chunxiao,  Li Jinyan,  Luo Lixia DOI: 10.3760/cma.j.issn.2095-0160.2018.07.004 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 500-507. Abstract                              [Download PDF] [Read Full Text] Objective To observe the expression dynamics of lens-related transcription factors in human embryonic stem cell (hESC) differentiated into lentoid body(LB). Methods A […]

Changes of mitochondrial dynamics related genes expression in a glaucoma rat model

Authors: Hu Xinxin,  Dai Yi,  Sun Xinghuai  DOI: 10.3760/cma.j.issn.2095-0160.2018.07.003 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 494-499. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the ultrastructural changes of mitochondria and dynamic changes of mitochondrial dynamics related genes in chronic ocular hypertension rat models. Methods […]

Importance of genetic and preimplantation genetic diagnosis in the prevention and treatment of inherited pediatric oculopathies

Authors: Chen Xue,  Zhao Chen DOI: 10.3760/cma.j.issn.2095-0160.2018.07.002 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 489-493. Abstract                              [Download PDF] [Read Full Text] Inherited pediatric oculopathies are a group of pediatric eye chiseases caused by genetic defects, and they are the primary causes […]

The research progress of macular telangiectasia type 2

Authors: Liu Chengxi,  Ding Xiaoyan DOI: 10.3760/cma.j.issn.2095-0160.2018.08.016 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 653-656. Abstract                               [Download PDF] [Read Full Text] Macular telangiectasia type 2 (MacTel type 2) is a kind of disease that characterized by the dilation of capillary in temporal macula lutea and […]

Recent advances of bevacizumab as an adjunct to trabeculectomy

Authors: Chen Juan,  Yu Wenzhen DOI: 10.3760/cma.j.issn.2095-0160.2018.08.015 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 649-652. Abstract                               [Download PDF] [Read Full Text] Glaucoma is a group of diseases characterized by progressive optic nerve damage and characteristic visual field defect.Increased intraocular pressure is the main risk factor […]

The relationship between primary open angle glaucoma and blood flow abnormalities

Authors: Tian Jiaxin,  Wang Ningli DOI: 10.3760/cma.j.issn.2095-0160.2018.08.014 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 643-648. Abstract                               [Download PDF] [Read Full Text] As one of the common types of glaucoma, primary open angle glaucoma (POAG) occurs insidiously with conditions, such as patients have normal intraocular pressure […]

Research progress of pathological relevant cytokines of neovascular eye diseases

Authors: Han Mengyu,  Wang Zhijun,  Jin Ming DOI: 10.3760/cma.j.issn.2095-0160.2018.08.013 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 636-642. Abstract                              [Download PDF] [Read Full Text] Neovascular eye diseases, with highly complicated and refractory, are one group of the most difficult problems for domestic and overseas clinical oculists in […]

Relationship between the changes of high-sensitivity C-reactive protein and retinal vessel diameter in the middle-aged and elderly: the Kailuan Study

Authors: Liu Xinxin,  Lu Aidong,  Wang Yaxing,  Wei Wenbin,  Chen Shuohua,  Wu Shouling DOI: 10.3760/cma.j.issn.2095-0160.2018.08.012 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 629-635. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the relationship between high-sensitivity C-reactive protein (hsCRP) and retinal vascular diameter. Methods This study was a cross-sectional […]