Category: 2019

The effect and mechanisms of chloride channel blocker NPPB on TGF-β1 induced HConF fibrosis

Authors: Sun Lixia,  Li Yingjun,  Cui Renzhe,  Lu Di,  Zheng Yajuan DOI: 10.3760/cma.j.issn.2095-0160.2019.06.003 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 411-418. Abstract                              [View PDF] [Read Full Text] Objective To study the effect and mechanisms of chloride channel blocker 5-Nitro-2-(3-phenylpropylamino) benzoic acid (NPPB) on thansforming growth factor β1 (TGF-β1) […]

The inhibitory effect of FoxF2 shRNA on the expression of extracellular matrix of human trabecular meshwork

Authors: Liu Aihua,  Gao Meizi,  Huang Liangyu,  Liu Xun,  Su Ruihong,  Zhao Jinzhi,  Wang Liming,  Zhang Xiaomin,  Li Xiaorong,  Dong Lijie DOI: 10.3760/cma.j.issn.2095-0160.2019.06.002 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 405-410. Abstract                               [View PDF] [Read Full Text] Objective To explore the role of forkhead box F2 (FoxF2) in the extracellular matrix of trabecular […]

Opportunities and challenges for glaucoma research

Author: Zhang Xiulan DOI: 10.3760/cma.j.issn.2095-0160.2019.06.001 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 401-404. Abstract                               [View PDF] [Read Full Text] Elevation of intraocular pressure (IOP) is the most eminent risk factor for the presence and progression of glaucoma, which leads to optic nerve damages ultimately.With […]

Current advance of polypoidal choroidal vasculopathy in diagnosis and treatment

Authors: Zhou Nan,  Wei Wenbin DOI: 10.3760/cma.j.issn.2095-0160.2019.01.017 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 77-80. Abstract                              [Download PDF] [Read Full Text] Polypoidal choroidal vasculopathy (PCV) is a kind of fundus disease characterized by choroidal anomalous branch vascular network and terminal polypoidal dilatation.The pathological basis of […]

Design and technical challenge of retinal prosthesis

Authors: Chen Bichi,  Lyu Fan DOI: 10.3760/cma.j.issn.2095-0160.2019.01.016 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 73-76. Abstract                              [Download PDF] [Read Full Text] Retinitis pigmentosa (RP) is a kind of hereditary disease characterized by progressive photoreceptor and pigmented epithelial cell dysfunction.It is also a common cause of […]

Role and mechanism of Müller cells in retinal injury

Authors:  Shi Xueying,  Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2019.01.015 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 69-72. Abstract                              [Download PDF] [Read Full Text] In mammalian retina, Müller cells are dominating macroglial cells and span the entire retina.These cells perform a variety of physiological roles to maitain the […]

Treatment of wet age-related macular degeneration: Now and future

Authors:  Ding Xiaoyan,  Wang Zhirong,  Sun Limei DOI: 10.3760/cma.j.issn.2095-0160.2019.01.014 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 63-68. Abstract                              [Download PDF] [Read Full Text] Wet age-related macular degeneration (AMD), which is the leading cause of visual impairment in elderly people, significantly affects quality of life of millions […]

Recent developments in neuro-ophthalmology

Author:  Cheng Zhang DOI: 10.3760/cma.j.issn.2095-0160.2019.01.013 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 55-62. Abstract                              [Download PDF] [Read Full Text] Some recent advances in neuro-ophthalmology including clinical trials, diagnostic testing and newly elucidated disease entitites were summarized in present paper, such as neuromyelitis optica spectrum […]

Effects of internal limiting membrane peeling during macular hole surgery on retinal anatomical and functional outcomes

Authors: He Qingyi,  Xie Zhenggao DOI: 10.3760/cma.j.issn.2095-0160.2019.01.012 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 51-54. Abstract                               [Download PDF] [Read Full Text] Idiopathic macular hole (IMH) refers to full thickness defects of retinal neuroepithelial layer in macular area without clear reasons, and the combination of pars […]

Treatment of idiopathic macular hole: internal limiting membrane peeling or inverted internal limiting membrane flap

Authors: Liu Guangfeng,  Jiang Yanrong DOI: 10.3760/cma.j.issn.2095-0160.2019.01.011 Published 2019-01-10 Cite as Chin J Exp Ophthalmol, 2019,37(1): 49-50. Abstract                               [Download PDF] [Read Full Text] Surgical management of idiopathic macular hole (IMH) is a hot topic in the field of fundus disease, and its classical surgery is internal limiting […]