Category: 2020, No. 10

Recent developments in lacrimal gland research and its implications in dry eye

Author: Chuanqing Ding DOI: 10.3760/cma.j.cn115989-20200814-00588 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 877-880. Abstract The lacrimal gland, as an essential component of the ocular surface system, along with its product, the tears, had not received sufficient attention in the past years.However, increasing evidence suggest that the lacrimal gland plays a critical role in […]

Advances in bone marrow mesenchymal stem cell transplantation for treatment of glaucomatous optic neuropathy

Authors: Wang Shujing,  Shao Zhengbo DOI: 10.3760/cma.j.cn115989-20200302-00131 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 881-884. Abstract Glaucoma is a disorder that leads to retinal ganglion cells (RGCs) apoptosis, visual field loss and optic nerve degeneration.The RGCs death is irreversible, which limites their ability for axon regeneration after injury.Bone marrow mesenchymal stem cells (BMSCs) […]

Progress in research of Müller cell reprogramming in retinal regeneration

Authors: Zhao Zhenzhen,  Liang Jian DOI: 10.3760/cma.j.cn115989-20200110-00019 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 885-889. Abstract Müller glia, the major type of glial cells in retina, is crucial for maintaining retinal homeostasis.Although Müller cells have the features to re-enter into the cell cycle and differentiate into neural cells for promoting retinal regeneration after […]

Modification of mesenchymal stem cell derived exosomes and its application prospects in the treatment of eye disease

Authors: Lin Hao,  Wang Ying DOI: 10.3760/cma.j.cn115989-20200319-00186 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 890-894. Abstract Mesenchymal stem cells (MSCs) were extensively explored as new therapeutic agents in cell-based therapy due to their immunomodulatory and pro-angiogenic characteristics.Exosomes are nanovesicles surrounded by a phospholipid layer.Recent studies have demonstrated that MSCs-derived exosomes (MSCs-exo) and MSCs […]

Advances in corneal basement membrane modulating stromal fibrosis

Authors: Wu Jinling,  Li Xia DOI: 10.3760/cma.j.cn115989-20200519-00355 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 895-899. Abstract Basement membranes are highly specialized forms of extracellular matrix and their formation is a prerequisite for normal tissue development and function.Basement membranes are important components of cornea.There are two types of basement membranes in cornea: epithelial basement […]

Progress in matrix metalloproteinase 2 and 9 regulating corneal neovascularization

Authors: Zhang Jiahao,  Zhang Yan,  He Yuxi DOI: 10.3760/cma.j.cn115989-20190226-00085 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 900-904. Abstract Corneal neovascularization (CNV) is a pathological process of angiogenesis that can cause severe corneal damage.CNV has been widely demonstrated to be closely related to corneal inflammation, mainly induced by the imbalance between pro-angiogenic factors and […]

Diagnosis and treatment of Goldenhar syndrome with bilateral chorioretinal dysplasia: a case report

Authors: Feng Bingkai,  Yang Jie,  Fan Ning,  Liu Xuyang DOI: 10.3760/cma.j.cn115989-20200923-00661 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 812-813. Contributor Information Feng Bingkai Shenzhen Eye Hospital, Shenzhen Key Laboratory of Ophthalmology, Jinan University, Shenzhen 518040, China Yang Jie Ningbo Aier Guangming Eye Hospital, Ningbo 315020, China Fan Ning Shenzhen Hospital of Southern Medical […]

Diagnosis and treatment of traumatic phakic astigmatism implantable collamer lens dislocation: a case report

Authors: He Zifang,  Bao Lianyun,  Chen Hui DOI: 10.3760/cma.j.cn115989-20190523-00229 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 827-828. Contributor Information He Zifang Ningyi Eye Center, Affiliated Drum-Tower Hospital of Medical College of Nanjing University, Nanjing 210008, China Bao Lianyun Ningyi Eye Center, Affiliated Drum-Tower Hospital of Medical College of Nanjing University, Nanjing 210008, China […]