Tag: Transdifferentiation

Inhibitory effect of indocyanine green on biological behavior and transdifferentiation of human lens epithelial cells and its mechanism

Authors: Liu Yajun,  Zhao Yingdi,  Zhang Wenwen,  Zhang Si,  He Zifang,  Chen Feifei,  Xie Zhenggao DOI: 10.3760/cma.j.cn115989-20220817-00380 Published 2023-12-10 Cite as Chin J Exp Ophthalmol, 2023, 41(12): 1160-1168. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the inhibitory effect of indocyanine […]

Promoting effect of connective tissue growth factor on expression of E-cadherin in human Tenon capsule fibroblasts

Authors: Li Jing,  Xie Anming DOI: 10.3760/cma.j.issn.2095-0160.2015.08.005 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 695-698. Abstract                              [Download PDF] [Read Full Text] Background Scarring of filtration channel following glaucoma filtering surgery is a main cause of the failure of the surgery. […]

Progress in research of Müller cell reprogramming in retinal regeneration

Authors: Zhao Zhenzhen,  Liang Jian DOI: 10.3760/cma.j.cn115989-20200110-00019 Published 2020-10-10 Cite as Chin J Exp Ophthalmol, 2020,38(10): 885-889. Abstract                               [View PDF] [Read Full Text] Müller glia, the major type of glial cells in retina, is crucial for maintaining retinal homeostasis.Although Müller cells have the features to […]

Effect of N-acetylcysteine on the transforming growth factor β1-induced transdifferentiation of retinal pigment epithelial cell to myofibroblast

Authors: Liu Shuai,  Jin Haiying DOI: 10.3760/cma.j.issn.2095-0160.2017.10.008 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 894-901. Abstract                              [Download PDF] [Read Full Text] Background The transdifferentiation of retinal pigment epithelial (RPE) cell to myofibroblast is a central event in the development and progression of proliferative vitreoretinopathy (PVR). […]