Category: 2020, No. 11

The importance of basic research and drug development for thyroid-associated ophthalmopathy

Author: Fan Xianqun DOI: 10.3760/cma.j.cn115989-20200812-00582 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 905-909. Abstract Thyroid-associated ophthalmopathy (TAO) is an organ specific autoimmune disease with complex pathogenesis.In recent years, great progress has been made in the pathogenesis of TAO primarily in immune and molecular mechanism aspects, including related autoantigens, lymphocytes, inflammatory factors, and autoimmune […]

Paying close attention to advanced researches of ocular surface mucin and significance in the diagnosis and management of dry eye

Author: Hong Jing DOI: 10.3760/cma.j.cn115989-20200715-00499 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 910-915. Abstract As an important part of the tear film, mucin can be divided into secretory mucin and membrane-associated mucin according to different functions.Secretory mucin, secreted by goblet cells, plays a key role in maintaining the stability of the tear film, […]

Stability evaluation of different internal fixation methods for zygomaticomaxillary complex fractures by finite element biomechanical analysis

Authors: Li Yan,  Wu Pengsen,  Ma Yue,  Tang Meiting,  Zeng Xueying,  Tang Yuanyuan,  Yu Shen,  Lu Wei DOI: 10.3760/cma.j.cn115989-20200727-00529 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 916-922. Abstract Objective To analyze the stability of different internal fixation methods for zygomaticomaxillary complex fracture using finite element biomechanical analysis and to provide a quantitative basis […]

Effects of IL-17A and IFN-γ on the fibrosis of CD34- orbital fibroblasts in Graves orbitopathy

Authors: Lu Yi,  Huang Yazhuo,  Li Yinwei,  Wu Yu,  Fang Sijie,  Sun Jing,  Zhou Huifang DOI: 10.3760/cma.j.cn115989-20200719-00513 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 923-928. Abstract Objective To observe the effects of interleukin-17A (IL-17A) and interferon-γ (IFN-γ) on CD34– orbital fibroblasts (OFs) in patients with Graves ophthalmopathy (GO), and to explore the pathogenesis […]

Inhibitory effects of resveratrol on high glucose-induced apoptosis of retinal cells

Authors: Li Qingchun,  Li Dai,  Xing Yiqiao DOI: 10.3760/cma.j.cn115989-20200519-00351 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 929-935. Abstract Objective To investigate the inhibitory effects of resveratrol (Res) on the apoptosis of retinal neurons of diabetic rats and ARPE-19 cells induced by high glucose. Methods Streptozotocin was intraperitoneally injected to establish a diabetes model […]

Effects of early applying basic fibroblast growth factor on corneal haze after surface ablation surgery and its mechanism

Authors: Sui Wenjun,  Gao Honglian,  Liu Qiqi,  Zhang Lei DOI: 10.3760/cma.j.cn115989-20190418-00190 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 936-943. Abstract Objective To investigate the effects of early applying of basic fibroblast growth factor (bFGF) on corneal haze formation after surface ablation surgery in rabbits. Methods The right eyes of 60 healthy New Zealand […]

Distribution of monocyte subtypes in peripheral blood of patients with thyroid-associated ophthalmopathy

Authors: Xu Jianan,  Ye Huijing,  Chen Rongxin,  Chen Guo,  Chen Jingqiao,  Yang Huasheng DOI: 10.3760/cma.j.cn115989-20200712-00489 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 944-950. Abstract Objective To explore the distribution of different subsets of monocyte in peripheral blood of patients with thyroid-associated ophthalmopathy (TAO). Methods A cross-sectional study was performed.Fifty-nine TAO patients and 30 […]

Protective effect of a modified orbital decompression for postoperative eye position in thyroid-associated ophthalmopathy

Authors: Zheng Songshan,  Chai Chang DOI: 10.3760/cma.j.cn115989-20200227-00114 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 951-956. Abstract Objective To investigate the protective effect of a modified orbital decompression on postoperative eye position in thyroid-associated ophthalmopathy (TAO). Methods A cohort study was performed.One hundred and thirty-six eyes of 96 TAO patients who received orbital decompression […]

X linked rod-cone dystrophy associated with a novel splicing variation in the intron of OPN1LW gene

Authors: Wu Zhong,  Shi Xiaomeng,  Li Ya,  You Ya,  Pei Han,  Lei Bo DOI: 10.3760/cma.j.cn115989-20200923-00662 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 957-961. Abstract Objective Mutations in the OPN1LW gene located in X chromosome usually lead to blue cone monochromacy.Variations in OPN1LW gene usually occur in the exon region, but was rare in […]

Agreement of biometry parameters measured by IOLMaster 700 and Pentacam AXL in cataract eyes

Authors: Li Dongjun,  Yang Wenli,  Wang Ziyang,  Chen Wei,  Zhao Qi,  Li Yifeng,  Cui Rui,  Shen Lin,  Xian Junfang DOI: 10.3760/cma.j.cn115989-20200924-00663 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 962-966. Abstract Objective To compare the agreement of biometric parameters measured by a new swept-source optical coherence tomography IOLMaster 700 and a new Scheimpflug imaging […]