Authors: Cheng Lei, Cheng Shan, Zhu Ran, Xu Guoxu DOI: 10.3760/cma.j.cn115989-20240806-00224 Published: 2025 -10 -10 Citation Cheng Lei, Cheng Shan, Zhu Ran, et al. Expression variations of different VEGFA isoforms in ARPE-19 cells under high glucose conditions[J]. Chin J Exp Ophthalmol, 2025, 43(10):892-902. DOI: 10.3760/cma.j.cn115989-20240806-00224. ABSTRACT [Download PDF] [View Full […]
Tag: Retinal pigment epithelial cells
Inhibitory effect of asparagine synthetase knockdown on retinal pigment epithelial cell senescence and its underlying mechanism
Authors: Ding Jie, Xin Xiangyang, Zhao Xin DOI: 10.3760/cma.j.cn115989-20241207-00337 Published: 2025 -07 -10 Citation Ding Jie, Xin Xiangyang, Zhao Xin. Inhibitory effect of asparagine synthetase knockdown on retinal pigment epithelial cell senescence and its underlying mechanism[J]. Chin J Exp Ophthalmol, 2025, 43(7):592-602. DOI: 10.3760/cma.j.cn115989-20241207-00337. ABSTRACT [Download PDF] [View Full Text] Objective […]
MeCP2-induced alterations of transcriptome and m6A modification in retinal pigment epithelial cell
Authors: Zhang Yongya, Li Xiaohua, Zhao Xueru, Li Xue DOI: 10.3760/cma.j.cn115989-20230920-00105 Published 2024-05-10 Cite as Chin J Exp Ophthalmol, 2024, 42(5): 408-416. Abstract [Download PDF] [Read Full Text] Objective To investigate mRNA and N6-methyladenosine (m6A) changes in retinal pigment epithelium (RPE) cells […]
Inhibitory effect of ZhuJing pill variant formula medicated serum on H2O2-induced epithelial-mesenchymal transition of human RPE cells and its mechanism
Authors: Shao Yan, Zhang Yuanzhong, Yang Ning, Hang Li, Chen Chunming, Li Min, Xu Xinrong DOI: 10.3760/cma.j.cn115989-20210907-00501 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1013-1022. Abstract [View PDF] [Read Full Text] Objective To study the effect of ZhuJing pill variant […]
Inhibitory effects of NADPH oxidase 4 inhibitor on the epithelial-mesenchymal transition of human RPE cells induced by bevacizumab
Auhtors: Xie Chaohui, Hao Xianghui, Yang Lingling, Xu Haifeng DOI: 10.3760/cma.j.cn115989-20210407-00234 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 507-513. Abstract [View PDF] [Read Full Text] Objective To observe the influence of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) 4 […]
All-trans retinoic acid-induced apoptosis signaling pathway in ARPE-19 cells
Authors: Wu Juan, Cui Dongmei, Yang Xiao, Zeng Junwen DOI: 10.3760/cma.j.cn115989-20190704-00293 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 490-497. Abstract [View PDF] [Read Full Text] Objective To investigate all-trans retinoic acid(ATRA)-induced apoptosis signaling pathway in ARPE-19 cells in vitro. Methods The APRE-19 cell […]
Protective effect and mechanism of esculetin on oxidative damaged ARPE-19 cells
Authors: Zhang Yingjun, Bai Ge, He Xiangdong, Zhang Donglei, He Wei DOI: 10.3760/cma.j.cn115989-20200224-00101 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1025-1031. Abstract [View PDF] [Read Full Text] Objective To study the protective effect and the mechanism of esculetin on oxidative-stressed human retinal pigment […]
Inhibitory effects of resveratrol on high glucose-induced apoptosis of retinal cells
Authors: Li Qingchun, Li Dai, Xing Yiqiao DOI: 10.3760/cma.j.cn115989-20200519-00351 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 929-935. Abstract [View PDF] [Read Full Text] Objective To investigate the inhibitory effects of resveratrol (Res) on the apoptosis of retinal neurons of diabetic rats and ARPE-19 […]
Protective effect of human umbilical cord mesenchymal stem cells on light-damaged retinal pigment epithelial cells
Authors: Zhuang Hong, Zhang Rong, Shu Qinmeng, Zhang Shujie, Xu Gezhi DOI: 10.3760/cma.j.issn.2095-0160.2019.11.003 Published 2019-11-10 Cite as Chin J Exp Ophthalmol, 2019,37(11): 863-869. Abstract [View PDF] [Read Full Text] Objective To investigate the protective effect of human umbilical cord mesenchymal stem cells (UCMSCs) on light-damaged retinal […]
Inhibiting effects of Src kinase inhibitor on TGF-β1 induced epithelial-mesenchymal transition of human RPE cells
Authors: He Jianfeng, Lyu Lixia, Luo Junjie, Li Zongyi, Shen Junhui, Xu Guotong, Gao Furong DOI: 10.3760/cma.j.issn.2095-0160.2018.01.002 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 5-11. Abstract [Download PDF] [Read Full Text] Objective To investigate the inhibiting effect of CGP77675 (CGP), a Src inhibitor, on epithelial-mesenchymal transition (EMT) of human retinal […]