Tag: Apoptosis

Inhibitory effect of stachydrine on high glucose-induced apoptosis in human lens epithelial cells and its mechanism

Authors: Wu Guijia, Chen Xiteng, Kou Zhenyu, Gao Nan, Bai Xiaomei, Mao Han, Jiang Yuanfeng, Dong Lijie, Tian Fang DOI: 10.3760/cma.j.cn115989-20240722-00204 Published:  2026 -03 -10 Citation Wu Guijia, Chen Xiteng, Kou Zhenyu, et al. Inhibitory effect of stachydrine on high glucose-induced apoptosis in human lens epithelial cells and its mechanism[J]. Chin J Exp Ophthalmol, 2026, 44(3):218-226. DOI: 10.3760/cma.j.cn115989-20240722-00204. […]

Research progress on retinal ganglion cell damage induced by glaucoma and programmed cell death pathways

Authors: Qin Minggao, Zhang Qiuli DOI: 10.3760/cma.j.cn115989-20241029-00301 Published: 2026 -03 -10 Citation Qin Minggao, Zhang Qiuli. Research progress on retinal ganglion cell damage induced by glaucoma and programmed cell death pathways[J]. Chin J Exp Ophthalmol, 2026, 44(3):301-306. DOI: 10.3760/cma.j.cn115989-20241029-00301. ABSTRACT                   [Download PDF]  [Read Full Text] Glaucoma, the second leading cause of global […]

Research status of retinal cell death in diabetic retinopathy

Authors: Yu Xinyue, Zhang Xiaomin Li Xiaorong DOI: 10.3760/cma.j.cn115989-20211109-00615 Published: 2025 -11 -10 Citation Yu Xinyue, Zhang Xiaomin Li Xiaorong. Research status of retinal cell death in diabetic retinopathy[J]. Chin J Exp Ophthalmol, 2025, 43(11):1076-1080. DOI: 10.3760/cma.j.cn115989-20211109-00615. ABSTRACT                   [Download PDF]  [Read Full Text] Programmed cell death is an important defense mechanism […]

Effect of circBPTF targeting miR-224-3p on high glucose induced human retinal vascular endothelial cells injury

Authors: Yang Huihui, Lei Xiang, Meng Zijun, Liu Huihong, Yu Lu, Yuan Huijuan DOI: 10.3760/cma.j.cn115989-20241128-00327 Published: 2025 -05 -10 Citation Yang Huihui, Lei Xiang, Meng Zijun, et al. Effect of circBPTF targeting miR-224-3p on high glucose induced human retinal vascular endothelial cells injury[J]. Chin J Exp Ophthalmol, 2025, 43(05):422-429. DOI: 10.3760/cma.j.cn115989-20241128-00327. [Download PDF] [View Full Text] ABSTRACT Objective  […]

Effect of 7, 8-dihydroxyflavone on NMDA-induced apoptosis of retinal ganglion cells

Authors: Zhu Jing, Huang Keke, Guo Juan DOI: 10.3760/cma.j.cn115989-20240201-00030 Published: 2025 -05 -10 Citation Zhu Jing, Huang Keke, Guo Juan. Effect of 7, 8-dihydroxyflavone on NMDA-induced apoptosis of retinal ganglion cells[J]. Chin J Exp Ophthalmol, 2025, 43(05):430-437. DOI: 10.3760/cma.j.cn115989-20240201-00030. [Download PDF] [View Full Text] ABSTRACT Objective  To investigate the effect of intravitreal injection of 7, 8-dihydroxyflavone (DHF) on N-methyl-D-aspartate […]

Research progress on the role of lncRNAs in the occurrence and development of glaucoma

Authors: Guan Ruijuan, Yan Xin, Kang Zefeng DOI: 10.3760/cma.j.cn115989-20220221-00068 Published: 2025 -05 -10 Citation Guan Ruijuan, Yan Xin, Kang Zefeng. Research progress on the role of lncRNAs in the occurrence and development of glaucoma[J]. Chin J Exp Ophthalmol, 2025, 43(05):466-470. DOI: 10.3760/cma.j.cn115989-20220221-00068. [Download PDF] [View Full Text] ABSTRACT Glaucoma refers to a group of heterogeneous eye diseases, which […]

Expression of long-chain non-coding RNA-P21 in hydrogen peroxide induced human lens epithelial cells damage

Authors: Dong Xiaoming,  Liu Yuxuan,  Ji Liyang,  Wang Jing,  Zhang Jinsong DOI: 10.3760/cma.j.cn115989-20221109-00522 Published 2024-03-10 Cite as Chin J Exp Ophthalmol, 2024, 42(3): 232-239. Abstract                               [Download PDF] [Read Full Text] Objective To detect the changes in the biological activity and expression of […]

Research progress on the inhibition of photoreceptor cell apoptosis by the pentose phosphate pathway and its molecular mechanism

Authors: Han Siyang,  Sun Xiaodong DOI: 10.3760/cma.j.cn115989-20210317-00179 Published 2024-01-10 Cite as Chin J Exp Ophthalmol, 2024, 42(1): 72-75. Abstract                              [Download PDF] [Read Full Text] Photoreceptor cells are a special type of neuroepithelial cells, which play an important role in the generation and […]

Inhibitory effect of specnuezhenide on high glucose-induced human retinal microvascular endothelial cell injury and its mechanism

Authors: Liu Qian,  Feng Xiaomei,  Liu Changgeng,  Li Haijun,  Yang Xiaoyuan,  Ren Jing,  Zhang Ying DOI: 10.3760/cma.j.cn115989-20211130-00662 Published 2023-04-10 Cite as Chin J Exp Ophthalmol, 2023, 41(4): 312-320. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the effect of specnuezhenide on […]

Antagonistic effect of SC79 on high glucose-induced apoptosis of RPE cells and its regulatory mechanism on AKT-XIAP signaling pathway

Authors: Zheng Lei,  Ma Dahui,  Chen Miaohong,  Zhang Guoming DOI: 10.3760/cma.j.cn115989-20210710-00405 Published 2023-03-10 Cite as Chin J Exp Ophthalmol, 2023, 41(3): 226-232. Abstract                               [Download PDF]  [Read Full Text] Objective To investigate the antagonistic effect and potential mechanism of specific AKT activator SC79 […]